ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	19/282	56/7206	1.14453633215e-13
ko04728	Dopaminergic synapse	29/282	185/7206	9.78749344559e-11
ko04080	Neuroactive ligand-receptor interaction	43/282	423/7206	4.62388563715e-09
ko04360	Axon guidance	29/282	233/7206	2.39050893035e-08
ko04721	Synaptic vesicle cycle	16/282	80/7206	5.56721577694e-08
ko04724	Glutamatergic synapse	22/282	152/7206	8.80948440464e-08
ko04514	Cell adhesion molecules (CAMs)	20/282	130/7206	1.24333205196e-07
ko04723	Retrograde endocannabinoid signaling	22/282	175/7206	1.07688535849e-06
ko05030	Cocaine addiction	13/282	73/7206	4.0077503133e-06
ko05032	Morphine addiction	16/282	110/7206	4.98609285282e-06
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/282	14/7206	7.84707504444e-06
ko04024	cAMP signaling pathway	27/282	279/7206	1.09587270324e-05
ko04727	GABAergic synapse	15/282	110/7206	2.19243735528e-05
ko04010	MAPK signaling pathway	27/282	321/7206	0.000159296502527
ko04713	Circadian entrainment	15/282	136/7206	0.000257902130417
ko04725	Cholinergic synapse	15/282	160/7206	0.00143835483486
ko05205	Proteoglycans in cancer	2/282	271/7206	0.00215216676599
ko05014	Amyotrophic lateral sclerosis (ALS)	9/282	74/7206	0.00224382314496
ko05031	Amphetamine addiction	10/282	91/7206	0.00279936706448
ko00603	Glycosphingolipid biosynthesis - globo and isoglobo series	3/282	8/7206	0.00286833380556
ko04950	Maturity onset diabetes of the young	5/282	29/7206	0.00485784630236
ko04062	Chemokine signaling pathway	1/282	201/7206	0.00494421614086
ko04911	Insulin secretion	11/282	117/7206	0.00591108168925
ko04261	Adrenergic signaling in cardiomyocytes	16/282	205/7206	0.00879426945747
ko05203	Viral carcinogenesis	3/282	277/7206	0.0102218018562
ko04150	mTOR signaling pathway	1/282	184/7206	0.0106287076601
ko04371	Apelin signaling pathway	1/282	177/7206	0.015921328913
ko04015	Rap1 signaling pathway	19/282	278/7206	0.0167208225863
ko04726	Serotonergic synapse	11/282	137/7206	0.0221833644209
ko05164	Influenza A	1/282	167/7206	0.0230270402772
ko04391	Hippo signaling pathway - fly	8/282	90/7206	0.0241063291704
ko04071	Sphingolipid signaling pathway	12/282	162/7206	0.0359318586733
ko00230	Purine metabolism	2/282	194/7206	0.0359483820939
ko05166	HTLV-I infection	5/282	292/7206	0.0446470522628
ko04120	Ubiquitin mediated proteolysis	1/282	138/7206	0.0449358930032
ko04218	Cellular senescence	2/282	177/7206	0.0489009790065
ko04217	Necroptosis	2/282	178/7206	0.0489541568648
ko05016	Huntington's disease	3/282	215/7206	0.0491308749937