ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	24/377	56/7206	8.05645514115e-17
ko04727	GABAergic synapse	30/377	110/7206	2.10385760636e-14
ko05032	Morphine addiction	28/377	110/7206	1.04945193001e-12
ko04080	Neuroactive ligand-receptor interaction	57/377	423/7206	1.52308280622e-11
ko04724	Glutamatergic synapse	31/377	152/7206	3.33689596862e-11
ko04713	Circadian entrainment	27/377	136/7206	1.23029872517e-09
ko04723	Retrograde endocannabinoid signaling	31/377	175/7206	1.37297792672e-09
ko04725	Cholinergic synapse	27/377	160/7206	4.80758163857e-08
ko04721	Synaptic vesicle cycle	18/377	80/7206	1.02809366148e-07
ko04911	Insulin secretion	22/377	117/7206	1.22079669112e-07
ko04728	Dopaminergic synapse	27/377	185/7206	1.00309778977e-06
ko04024	cAMP signaling pathway	35/377	279/7206	1.25102205951e-06
ko04744	Phototransduction	9/377	36/7206	7.11984258677e-05
ko05030	Cocaine addiction	13/377	73/7206	8.78920209396e-05
ko05031	Amphetamine addiction	14/377	91/7206	0.000241862502715
ko04726	Serotonergic synapse	18/377	137/7206	0.00025956081199
ko04710	Circadian rhythm	9/377	43/7206	0.00030798605344
ko04925	Aldosterone synthesis and secretion	15/377	105/7206	0.000337479829177
ko04010	MAPK signaling pathway	31/377	321/7206	0.000771396146843
ko04742	Taste transduction	10/377	61/7206	0.00112061461737
ko04970	Salivary secretion	13/377	95/7206	0.00125129910011
ko04921	Oxytocin signaling pathway	22/377	209/7206	0.00144266328536
ko04072	Phospholipase D signaling pathway	21/377	197/7206	0.00168336231445
ko04020	Calcium signaling pathway	26/377	265/7206	0.00173541202467
ko04930	Type II diabetes mellitus	9/377	54/7206	0.00174568202402
ko04145	Phagosome	1/377	162/7206	0.00344588085638
ko04014	Ras signaling pathway	26/377	279/7206	0.00365405222503
ko05322	Systemic lupus erythematosus	1/377	151/7206	0.00482269075528
ko00604	Glycosphingolipid biosynthesis - ganglio series	4/377	14/7206	0.0048544481418
ko04261	Adrenergic signaling in cardiomyocytes	20/377	205/7206	0.00623847344411
ko04730	Long-term depression	10/377	78/7206	0.00710760594538
ko05205	Proteoglycans in cancer	5/377	271/7206	0.007565622039
ko04070	Phosphatidylinositol signaling system	13/377	112/7206	0.00778197566239
ko04144	Endocytosis	29/377	342/7206	0.00869713006234
ko04071	Sphingolipid signaling pathway	16/377	162/7206	0.0119475168171
ko04015	Rap1 signaling pathway	24/377	278/7206	0.0132147902704
ko00190	Oxidative phosphorylation	1/377	127/7206	0.0146716102568
ko05203	Viral carcinogenesis	6/377	277/7206	0.0181411442875
ko04720	Long-term potentiation	11/377	99/7206	0.0186494018897
ko05016	Huntington's disease	4/377	215/7206	0.0189185817656
ko04810	Regulation of actin cytoskeleton	6/377	264/7206	0.0236200183043
ko04217	Necroptosis	3/377	178/7206	0.0257607421097
ko04022	cGMP-PKG signaling pathway	19/377	216/7206	0.0277976840428
ko00240	Pyrimidine metabolism	1/377	110/7206	0.030571585304
ko04961	Endocrine and other factor-regulated calcium reabsorption	7/377	59/7206	0.0332232091799
ko02024	Quorum sensing	3/377	15/7206	0.0404362786112
ko04540	Gap junction	12/377	128/7206	0.0431148782958
ko04924	Renin secretion	9/377	86/7206	0.0445900736373
ko04514	Cell adhesion molecules (CAMs)	12/377	130/7206	0.0461781498735
ko04972	Pancreatic secretion	11/377	111/7206	0.0477890822891
ko04915	Estrogen signaling pathway	12/377	131/7206	0.0478381238822
ko05164	Influenza A	3/377	167/7206	0.0499311740289