ko pathway ratio_in_study ratio_in_pop p_value ko04380 Osteoclast differentiation 19/219 134/7206 1.73476692982e-08 ko05140 Leishmaniasis 13/219 75/7206 3.16161662225e-07 ko04064 NF-kappa B signaling pathway 14/219 96/7206 9.96687017961e-07 ko04621 NOD-like receptor signaling pathway 18/219 157/7206 1.09885713177e-06 ko04060 Cytokine-cytokine receptor interaction 20/219 191/7206 1.17389774473e-06 ko04620 Toll-like receptor signaling pathway 14/219 100/7206 1.65242704933e-06 ko05168 Herpes simplex infection 19/219 182/7206 2.30277343839e-06 ko05164 Influenza A 18/219 167/7206 2.71474633495e-06 ko05162 Measles 15/219 120/7206 3.01756531403e-06 ko04668 TNF signaling pathway 15/219 120/7206 3.01756531403e-06 ko05145 Toxoplasmosis 15/219 126/7206 5.58343802211e-06 ko04630 Jak-STAT signaling pathway 15/219 132/7206 9.94282889455e-06 ko04622 RIG-I-like receptor signaling pathway 10/219 62/7206 1.47455797388e-05 ko05340 Primary immunodeficiency 7/219 30/7206 2.43969231594e-05 ko05150 Staphylococcus aureus infection 7/219 36/7206 8.56468763898e-05 ko04611 Platelet activation 15/219 163/7206 0.000120074873628 ko04137 Mitophagy - animal 10/219 82/7206 0.000172558696685 ko04623 Cytosolic DNA-sensing pathway 7/219 41/7206 0.000202712983804 ko05161 Hepatitis B 15/219 173/7206 0.000233139315011 ko05321 Inflammatory bowel disease (IBD) 8/219 56/7206 0.000258623487934 ko00120 Primary bile acid biosynthesis 5/219 20/7206 0.000264356667336 ko05323 Rheumatoid arthritis 10/219 89/7206 0.000340784747163 ko05152 Tuberculosis 15/219 187/7206 0.000539377982425 ko05160 Hepatitis C 13/219 153/7206 0.000736900478371 ko04672 Intestinal immune network for IgA production 6/219 37/7206 0.000776897796544 ko04217 Necroptosis 14/219 178/7206 0.000999857545413 ko04662 B cell receptor signaling pathway 9/219 88/7206 0.001333566425 ko05134 Legionellosis 8/219 74/7206 0.00171814756362 ko04080 Neuroactive ligand-receptor interaction 3/219 423/7206 0.00181617259099 ko05144 Malaria 6/219 45/7206 0.00222389594528 ko04610 Complement and coagulation cascades 8/219 79/7206 0.00261274330971 ko05133 Pertussis 8/219 87/7206 0.00475879153516 ko05142 Chagas disease (American trypanosomiasis) 10/219 130/7206 0.00606396796565 ko05167 Kaposi's sarcoma-associated herpesvirus infection 13/219 191/7206 0.00786110287889 ko04658 Th1 and Th2 cell differentiation 8/219 96/7206 0.00856389325072 ko04612 Antigen processing and presentation 7/219 77/7206 0.0086223329144 ko04664 Fc epsilon RI signaling pathway 7/219 77/7206 0.0086223329144 ko04650 Natural killer cell mediated cytotoxicity 8/219 97/7206 0.00909672452339 ko04062 Chemokine signaling pathway 13/219 201/7206 0.00993700362673 ko05034 Alcoholism 1/219 238/7206 0.0107685626404 ko05310 Asthma 3/219 17/7206 0.0137399732866 ko04659 Th17 cell differentiation 8/219 106/7206 0.0150679392497 ko04917 Prolactin signaling pathway 7/219 87/7206 0.0162607620821 ko04145 Phagosome 11/219 162/7206 0.016567942496 ko00592 alpha-Linolenic acid metabolism 3/219 19/7206 0.0187271585516 ko00590 Arachidonic acid metabolism 5/219 52/7206 0.0201986802243 ko04666 Fc gamma R-mediated phagocytosis 8/219 122/7206 0.0319801549183 ko05169 Epstein-Barr virus infection 12/219 206/7206 0.0349231500024 ko05330 Allograft rejection 3/219 24/7206 0.0350194515992 ko04640 Hematopoietic cell lineage 5/219 64/7206 0.0443664907422 ko04728 Dopaminergic synapse 1/219 185/7206 0.0465141115019 ko04657 IL-17 signaling pathway 6/219 87/7206 0.0484933462106