ko pathway ratio_in_study ratio_in_pop p_value ko04710 Circadian rhythm 11/355 43/7206 4.92431817523e-06 ko04070 Phosphatidylinositol signaling system 18/355 112/7206 7.65928066927e-06 ko04925 Aldosterone synthesis and secretion 14/355 105/7206 0.000591141477698 ko04750 Inflammatory mediator regulation of TRP channels 15/355 122/7206 0.000906164187966 ko00564 Glycerophospholipid metabolism 13/355 99/7206 0.00106484230867 ko00592 alpha-Linolenic acid metabolism 5/355 19/7206 0.00184921616278 ko04137 Mitophagy - animal 11/355 82/7206 0.00213705652189 ko04745 Phototransduction - fly 7/355 38/7206 0.00222870001845 ko00120 Primary bile acid biosynthesis 5/355 20/7206 0.00236737722874 ko04725 Cholinergic synapse 17/355 160/7206 0.00246487814381 ko04022 cGMP-PKG signaling pathway 21/355 216/7206 0.00334182433098 ko04020 Calcium signaling pathway 24/355 265/7206 0.00344466460745 ko00140 Steroid hormone biosynthesis 7/355 41/7206 0.00349744426938 ko04960 Aldosterone-regulated sodium reabsorption 7/355 41/7206 0.00349744426938 ko00590 Arachidonic acid metabolism 8/355 52/7206 0.00359997457228 ko00051 Fructose and mannose metabolism 7/355 42/7206 0.00402352582353 ko04024 cAMP signaling pathway 25/355 279/7206 0.00416607627497 ko04072 Phospholipase D signaling pathway 19/355 197/7206 0.00420955787951 ko05321 Inflammatory bowel disease (IBD) 8/355 56/7206 0.00572864155272 ko04970 Salivary secretion 11/355 95/7206 0.00674436057659 ko04650 Natural killer cell mediated cytotoxicity 11/355 97/7206 0.00787330859762 ko04726 Serotonergic synapse 14/355 137/7206 0.00826924318948 ko04918 Thyroid hormone synthesis 10/355 86/7206 0.00931672671234 ko04626 Plant-pathogen interaction 4/355 18/7206 0.0102253375774 ko03040 Spliceosome 1/355 145/7206 0.0103121446754 ko04110 Cell cycle 1/355 145/7206 0.0103121446754 ko04922 Glucagon signaling pathway 13/355 128/7206 0.0115679808923 ko05031 Amphetamine addiction 10/355 91/7206 0.0136238218267 ko05340 Primary immunodeficiency 5/355 30/7206 0.0145331404232 ko05152 Tuberculosis 17/355 187/7206 0.0147142645729 ko04911 Insulin secretion 12/355 117/7206 0.0148396991452 ko04610 Complement and coagulation cascades 9/355 79/7206 0.0151077355321 ko04919 Thyroid hormone signaling pathway 14/355 143/7206 0.0163754265901 ko05230 Central carbon metabolism in cancer 9/355 81/7206 0.0175820414682 ko04530 Tight junction 4/355 228/7206 0.0189868145948 ko04066 HIF-1 signaling pathway 12/355 123/7206 0.0195980924454 ko04921 Oxytocin signaling pathway 18/355 209/7206 0.0212332465044 ko03010 Ribosome 1/355 129/7206 0.0216239663322 ko04711 Circadian rhythm - fly 3/355 13/7206 0.023450565878 ko05164 Influenza A 15/355 167/7206 0.0269831845848 ko04971 Gastric acid secretion 10/355 98/7206 0.0287984568905 ko00330 Arginine and proline metabolism 7/355 61/7206 0.0293934654323 ko04720 Long-term potentiation 10/355 99/7206 0.0298971299353 ko05145 Toxoplasmosis 12/355 126/7206 0.0334505391951 ko00561 Glycerolipid metabolism 7/355 63/7206 0.0343139217132 ko05322 Systemic lupus erythematosus 2/355 151/7206 0.0347299622827 ko04060 Cytokine-cytokine receptor interaction 16/355 191/7206 0.0391507987128 ko04380 Osteoclast differentiation 12/355 134/7206 0.0408240906943 ko05231 Choline metabolism in cancer 12/355 134/7206 0.0408240906943 ko00230 Purine metabolism 16/355 194/7206 0.0412542897099 ko04140 Autophagy - animal 14/355 164/7206 0.0419709246723 ko02025 Biofilm formation - Pseudomonas aeruginosa 1/355 1/7206 0.0492645018042