ko pathway ratio_in_study ratio_in_pop p_value ko04710 Circadian rhythm 10/304 43/7206 8.54472488522e-06 ko04070 Phosphatidylinositol signaling system 14/304 112/7206 0.000239978495618 ko00010 Glycolysis / Gluconeogenesis 11/304 74/7206 0.000243725280224 ko00051 Fructose and mannose metabolism 8/304 42/7206 0.000307952333474 ko00564 Glycerophospholipid metabolism 12/304 99/7206 0.000876407313087 ko00120 Primary bile acid biosynthesis 5/304 20/7206 0.00118774047168 ko05031 Amphetamine addiction 11/304 91/7206 0.0014593335645 ko04922 Glucagon signaling pathway 13/304 128/7206 0.00278884088337 ko01230 Biosynthesis of amino acids 10/304 85/7206 0.00290829627328 ko04744 Phototransduction 6/304 36/7206 0.00358278042983 ko02010 ABC transporters 6/304 39/7206 0.00539854359906 ko05230 Central carbon metabolism in cancer 9/304 81/7206 0.00678895477354 ko00592 alpha-Linolenic acid metabolism 4/304 19/7206 0.00728160049867 ko00290 Valine, leucine and isoleucine biosynthesis 2/304 4/7206 0.0100591737595 ko00030 Pentose phosphate pathway 5/304 32/7206 0.0101987578318 ko04072 Phospholipase D signaling pathway 16/304 197/7206 0.0106884402633 ko00052 Galactose metabolism 5/304 33/7206 0.0116154385066 ko05323 Rheumatoid arthritis 9/304 89/7206 0.0123499696185 ko04724 Glutamatergic synapse 13/304 152/7206 0.0130529487998 ko00680 Methane metabolism 5/304 34/7206 0.0131603251152 ko04711 Circadian rhythm - fly 3/304 13/7206 0.0155173585053 ko00561 Glycerolipid metabolism 7/304 63/7206 0.0162157846735 ko04745 Phototransduction - fly 5/304 38/7206 0.020713595784 ko00590 Arachidonic acid metabolism 6/304 52/7206 0.0213651358588 ko05322 Systemic lupus erythematosus 1/304 151/7206 0.0219659654095 ko04966 Collecting duct acid secretion 4/304 26/7206 0.0222910678776 ko04930 Type II diabetes mellitus 6/304 54/7206 0.0252831741449 ko04020 Calcium signaling pathway 19/304 265/7206 0.0272022418573 ko00140 Steroid hormone biosynthesis 5/304 41/7206 0.0279313498788 ko04960 Aldosterone-regulated sodium reabsorption 5/304 41/7206 0.0279313498788 ko04120 Ubiquitin mediated proteolysis 1/304 138/7206 0.0311465154525 ko03040 Spliceosome 1/304 145/7206 0.0328090452956 ko04720 Long-term potentiation 9/304 99/7206 0.0369927642001 ko04750 Inflammatory mediator regulation of TRP channels 10/304 122/7206 0.0378529009258 ko04626 Plant-pathogen interaction 3/304 18/7206 0.0379139292374 ko04066 HIF-1 signaling pathway 10/304 123/7206 0.0392696501999 ko00901 Indole alkaloid biosynthesis 1/304 1/7206 0.0421870663338 ko02025 Biofilm formation - Pseudomonas aeruginosa 1/304 1/7206 0.0421870663338 ko03010 Ribosome 1/304 129/7206 0.0448288228049 ko04730 Long-term depression 7/304 78/7206 0.0455989481447 ko04152 AMPK signaling pathway 12/304 161/7206 0.0465142737102 ko04726 Serotonergic synapse 11/304 137/7206 0.0480710388783 ko03013 RNA transport 2/304 166/7206 0.0489030647219