ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	59/644	152/7206	3.4546392442e-24
ko05033	Nicotine addiction	34/644	56/7206	3.13168198492e-22
ko04727	GABAergic synapse	46/644	110/7206	1.20702547168e-20
ko05032	Morphine addiction	45/644	110/7206	9.31862595367e-20
ko04721	Synaptic vesicle cycle	38/644	80/7206	1.3249254446e-19
ko04723	Retrograde endocannabinoid signaling	53/644	175/7206	2.85996059111e-16
ko04725	Cholinergic synapse	49/644	160/7206	2.45099407097e-15
ko04728	Dopaminergic synapse	53/644	185/7206	3.93062209178e-15
ko04080	Neuroactive ligand-receptor interaction	88/644	423/7206	9.59317369837e-15
ko04713	Circadian entrainment	43/644	136/7206	3.8243279556e-14
ko04911	Insulin secretion	37/644	117/7206	2.42361583075e-12
ko04024	cAMP signaling pathway	61/644	279/7206	1.97347398927e-11
ko04744	Phototransduction	18/644	36/7206	2.05136173145e-10
ko04261	Adrenergic signaling in cardiomyocytes	47/644	205/7206	7.76586150751e-10
ko04726	Serotonergic synapse	33/644	137/7206	7.97330605704e-08
ko04921	Oxytocin signaling pathway	42/644	209/7206	3.95170998061e-07
ko04970	Salivary secretion	24/644	95/7206	1.92672238877e-06
ko04514	Cell adhesion molecules (CAMs)	29/644	130/7206	2.66901144002e-06
ko04010	MAPK signaling pathway	53/644	321/7206	8.18833660301e-06
ko04020	Calcium signaling pathway	46/644	265/7206	8.42081635303e-06
ko04972	Pancreatic secretion	25/644	111/7206	1.08952681477e-05
ko03040	Spliceosome	1/644	145/7206	2.62361810407e-05
ko04260	Cardiac muscle contraction	22/644	98/7206	3.85483536114e-05
ko05030	Cocaine addiction	18/644	73/7206	5.24190481572e-05
ko04360	Axon guidance	40/644	233/7206	5.3339056675e-05
ko04742	Taste transduction	16/644	61/7206	6.08324261623e-05
ko04022	cGMP-PKG signaling pathway	37/644	216/7206	8.79269396974e-05
ko05203	Viral carcinogenesis	8/644	277/7206	8.89137899488e-05
ko05031	Amphetamine addiction	20/644	91/7206	0.000117729466524
ko04964	Proximal tubule bicarbonate reclamation	10/644	29/7206	0.000126229209987
ko04730	Long-term depression	18/644	78/7206	0.000132393384546
ko05322	Systemic lupus erythematosus	2/644	151/7206	0.000136226829326
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	18/644	79/7206	0.000157483122412
ko03013	RNA transport	3/644	166/7206	0.000267968818407
ko05168	Herpes simplex infection	4/644	182/7206	0.000319160693772
ko04720	Long-term potentiation	20/644	99/7206	0.000478765190457
ko04930	Type II diabetes mellitus	13/644	54/7206	0.000726964157524
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/644	14/7206	0.000799217808968
ko04072	Phospholipase D signaling pathway	32/644	197/7206	0.000840793651545
ko05205	Proteoglycans in cancer	10/644	271/7206	0.001023483133
ko04966	Collecting duct acid secretion	8/644	26/7206	0.0014203847923
ko05414	Dilated cardiomyopathy	20/644	112/7206	0.00227984078838
ko04960	Aldosterone-regulated sodium reabsorption	10/644	41/7206	0.00264281919183
ko04060	Cytokine-cytokine receptor interaction	6/644	191/7206	0.00276122486132
ko04973	Carbohydrate digestion and absorption	10/644	42/7206	0.00319740369597
ko05110	Vibrio cholerae infection	13/644	63/7206	0.00324962627542
ko05164	Influenza A	5/644	167/7206	0.00361869667181
ko04141	Protein processing in endoplasmic reticulum	6/644	184/7206	0.00366868461502
ko04961	Endocrine and other factor-regulated calcium reabsorption	12/644	59/7206	0.00521288138269
ko04621	NOD-like receptor signaling pathway	5/644	157/7206	0.00679296666819
ko04071	Sphingolipid signaling pathway	25/644	162/7206	0.00733481678761
ko04925	Aldosterone synthesis and secretion	18/644	105/7206	0.00835797200266
ko04120	Ubiquitin mediated proteolysis	4/644	138/7206	0.00943781832393
ko04137	Mitophagy - animal	1/644	82/7206	0.00952924868833
ko05410	Hypertrophic cardiomyopathy (HCM)	17/644	100/7206	0.0117579523372
ko04070	Phosphatidylinositol signaling system	18/644	112/7206	0.0118832330438
ko05140	Leishmaniasis	1/644	75/7206	0.0132179587243
ko04976	Bile secretion	14/644	80/7206	0.0153871077526
ko00240	Pyrimidine metabolism	3/644	110/7206	0.0171473736053
ko05169	Epstein-Barr virus infection	9/644	206/7206	0.017821087113
ko04915	Estrogen signaling pathway	20/644	131/7206	0.0187904738798
ko04144	Endocytosis	43/644	342/7206	0.019509742148
ko04214	Apoptosis - fly	1/644	72/7206	0.0197595989097
ko05014	Amyotrophic lateral sclerosis (ALS)	13/644	74/7206	0.0209849095267
ko05016	Huntington's disease	10/644	215/7206	0.0210249702654
ko04924	Renin secretion	14/644	86/7206	0.0223353517378
ko04740	Olfactory transduction	13/644	80/7206	0.0289165921229
ko05131	Shigellosis	2/644	82/7206	0.0316449222092
ko04971	Gastric acid secretion	15/644	98/7206	0.0322640888574
ko04217	Necroptosis	8/644	178/7206	0.0327695964897
ko04810	Regulation of actin cytoskeleton	14/644	264/7206	0.0360022252935
ko00562	Inositol phosphate metabolism	14/644	89/7206	0.0366181699026
ko04110	Cell cycle	6/644	145/7206	0.0387621248848
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	4/644	15/7206	0.0388884491496
ko00330	Arginine and proline metabolism	1/644	61/7206	0.0406691635278
ko05161	Hepatitis B	8/644	173/7206	0.0425347778285
ko04640	Hematopoietic cell lineage	1/644	64/7206	0.0428806530145
ko04612	Antigen processing and presentation	2/644	77/7206	0.044608049221
ko04064	NF-kappa B signaling pathway	3/644	96/7206	0.0455186914752
ko00513	Various types of N-glycan biosynthesis	8/644	42/7206	0.0495552064181