ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	137/801	423/7206	2.46745031398e-34
ko04724	Glutamatergic synapse	73/801	152/7206	7.94243628282e-31
ko05033	Nicotine addiction	41/801	56/7206	9.53228221037e-28
ko04727	GABAergic synapse	52/801	110/7206	8.30410037178e-22
ko05032	Morphine addiction	52/801	110/7206	8.30410037178e-22
ko04744	Phototransduction	27/801	36/7206	4.10979267931e-19
ko04713	Circadian entrainment	55/801	136/7206	4.68443281538e-19
ko04723	Retrograde endocannabinoid signaling	62/801	175/7206	6.49727233321e-18
ko04728	Dopaminergic synapse	62/801	185/7206	1.47521722776e-16
ko04721	Synaptic vesicle cycle	36/801	80/7206	1.28297120242e-14
ko04742	Taste transduction	31/801	61/7206	1.35855100237e-14
ko04725	Cholinergic synapse	52/801	160/7206	1.85926745234e-13
ko04726	Serotonergic synapse	47/801	137/7206	2.96580027675e-13
ko04024	cAMP signaling pathway	73/801	279/7206	7.4621854422e-13
ko04740	Olfactory transduction	33/801	80/7206	3.31154735676e-12
ko04911	Insulin secretion	41/801	117/7206	4.60437642247e-12
ko04970	Salivary secretion	32/801	95/7206	3.31271952385e-09
ko04921	Oxytocin signaling pathway	53/801	209/7206	4.04066024915e-09
ko05031	Amphetamine addiction	30/801	91/7206	1.81780397846e-08
ko04261	Adrenergic signaling in cardiomyocytes	51/801	205/7206	2.29588131209e-08
ko04020	Calcium signaling pathway	60/801	265/7206	4.0566679871e-08
ko05030	Cocaine addiction	25/801	73/7206	1.21500585164e-07
ko04720	Long-term potentiation	30/801	99/7206	1.54846272745e-07
ko04976	Bile secretion	26/801	80/7206	2.24712843861e-07
ko05203	Viral carcinogenesis	8/801	277/7206	4.57016173493e-07
ko03040	Spliceosome	1/801	145/7206	1.35924779648e-06
ko04978	Mineral absorption	16/801	40/7206	2.23413250005e-06
ko04972	Pancreatic secretion	30/801	111/7206	2.31949447739e-06
ko04120	Ubiquitin mediated proteolysis	1/801	138/7206	3.08933462203e-06
ko04971	Gastric acid secretion	27/801	98/7206	4.98750504785e-06
ko05164	Influenza A	3/801	167/7206	8.20294351833e-06
ko05162	Measles	1/801	120/7206	2.321463725e-05
ko04925	Aldosterone synthesis and secretion	27/801	105/7206	2.38597359858e-05
ko04730	Long-term depression	22/801	78/7206	2.49194972041e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	21/801	74/7206	3.43117678325e-05
ko05322	Systemic lupus erythematosus	3/801	151/7206	3.62680764546e-05
ko04974	Protein digestion and absorption	24/801	96/7206	0.000104331273342
ko04260	Cardiac muscle contraction	24/801	98/7206	0.000140669154632
ko04022	cGMP-PKG signaling pathway	43/801	216/7206	0.000151724876581
ko04964	Proximal tubule bicarbonate reclamation	11/801	29/7206	0.000156253884102
ko04540	Gap junction	29/801	128/7206	0.000160057274294
ko05168	Herpes simplex infection	6/801	182/7206	0.000178758030848
ko04932	Non-alcoholic fatty liver disease (NAFLD)	6/801	182/7206	0.000178758030848
ko03013	RNA transport	5/801	166/7206	0.000232321632793
ko04010	MAPK signaling pathway	57/801	321/7206	0.000258868966807
ko04060	Cytokine-cytokine receptor interaction	7/801	191/7206	0.00026563456775
ko05169	Epstein-Barr virus infection	8/801	206/7206	0.000275651087964
ko05205	Proteoglycans in cancer	13/801	271/7206	0.000345430247098
ko05166	HTLV-I infection	15/801	292/7206	0.000403833857555
ko04141	Protein processing in endoplasmic reticulum	7/801	184/7206	0.000506955029804
ko04514	Cell adhesion molecules (CAMs)	28/801	130/7206	0.000565795644803
ko04924	Renin secretion	20/801	86/7206	0.00139485368881
ko03008	Ribosome biogenesis in eukaryotes	1/801	79/7206	0.00176362300576
ko04621	NOD-like receptor signaling pathway	6/801	157/7206	0.00181355302766
ko05215	Prostate cancer	3/801	111/7206	0.00201283964019
ko04745	Phototransduction - fly	11/801	38/7206	0.00212916191196
ko04217	Necroptosis	8/801	178/7206	0.00239880423924
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	18/801	79/7206	0.00309199770781
ko04350	TGF-beta signaling pathway	3/801	103/7206	0.00404203326122
ko05161	Hepatitis B	8/801	173/7206	0.00445208281791
ko04110	Cell cycle	6/801	145/7206	0.0046263565383
ko00830	Retinol metabolism	11/801	42/7206	0.00500877111101
ko04961	Endocrine and other factor-regulated calcium reabsorption	14/801	59/7206	0.00530773372473
ko05145	Toxoplasmosis	5/801	126/7206	0.00626359839938
ko03018	RNA degradation	2/801	84/7206	0.00754961503995
ko04064	NF-kappa B signaling pathway	3/801	96/7206	0.00811266592886
ko05414	Dilated cardiomyopathy	22/801	112/7206	0.00896577867563
ko04630	Jak-STAT signaling pathway	6/801	132/7206	0.0114427151051
ko04668	TNF signaling pathway	5/801	120/7206	0.0118927986763
ko04150	mTOR signaling pathway	10/801	184/7206	0.0119404712884
ko00330	Arginine and proline metabolism	1/801	61/7206	0.0123798500258
ko04330	Notch signaling pathway	1/801	62/7206	0.012730654984
ko00310	Lysine degradation	2/801	73/7206	0.0147146656592
ko05016	Huntington's disease	13/801	215/7206	0.0148642702779
ko05140	Leishmaniasis	2/801	75/7206	0.0148758576051
ko04072	Phospholipase D signaling pathway	33/801	197/7206	0.0152473583469
ko04218	Cellular senescence	10/801	177/7206	0.0153052046658
ko04140	Autophagy - animal	9/801	164/7206	0.0166788449888
ko04931	Insulin resistance	7/801	137/7206	0.019441456606
ko04750	Inflammatory mediator regulation of TRP channels	22/801	122/7206	0.0194866353378
ko05224	Breast cancer	10/801	174/7206	0.0198947509914
ko04966	Collecting duct acid secretion	7/801	26/7206	0.0202341276982
ko04973	Carbohydrate digestion and absorption	10/801	42/7206	0.0216166134926
ko05220	Chronic myeloid leukemia	3/801	85/7206	0.0224622103616
ko04915	Estrogen signaling pathway	23/801	131/7206	0.0240126995182
ko04210	Apoptosis	11/801	180/7206	0.0299356068556
ko05217	Basal cell carcinoma	2/801	68/7206	0.0304681334365
ko05200	Pathways in cancer	40/801	492/7206	0.0308390032669
ko04610	Complement and coagulation cascades	3/801	79/7206	0.0309686694155
ko05211	Renal cell carcinoma	4/801	96/7206	0.0314950447468
ko04070	Phosphatidylinositol signaling system	20/801	112/7206	0.032189346806
ko04550	Signaling pathways regulating pluripotency of stem cells	10/801	165/7206	0.0331479144341
ko05202	Transcriptional misregulation in cancer	12/801	188/7206	0.0341040349795
ko04810	Regulation of actin cytoskeleton	19/801	264/7206	0.0362919062505
ko04918	Thyroid hormone synthesis	16/801	86/7206	0.0363487718788
ko05219	Bladder cancer	1/801	48/7206	0.0384307547229
ko04960	Aldosterone-regulated sodium reabsorption	9/801	41/7206	0.0409331183354
ko04146	Peroxisome	4/801	89/7206	0.0416472707089
ko05222	Small cell lung cancer	4/801	89/7206	0.0416472707089
ko00561	Glycerolipid metabolism	2/801	63/7206	0.0424458128697
ko01524	Platinum drug resistance	3/801	76/7206	0.0428882531918
ko04612	Antigen processing and presentation	3/801	77/7206	0.0431494813544
ko05152	Tuberculosis	12/801	187/7206	0.0438983732654
ko04142	Lysosome	9/801	151/7206	0.0481800359814
ko04910	Insulin signaling pathway	11/801	172/7206	0.0486100913496