ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	29/708	56/7206	1.9649172924e-15
ko04080	Neuroactive ligand-receptor interaction	94/708	423/7206	5.24614073908e-15
ko04724	Glutamatergic synapse	49/708	152/7206	1.1068604147e-14
ko04727	GABAergic synapse	38/708	110/7206	1.03504176297e-12
ko04728	Dopaminergic synapse	51/708	185/7206	3.03458452107e-12
ko04911	Insulin secretion	37/708	117/7206	4.15657253029e-11
ko04713	Circadian entrainment	40/708	136/7206	8.3192812027e-11
ko04260	Cardiac muscle contraction	32/708	98/7206	3.50732135552e-10
ko04261	Adrenergic signaling in cardiomyocytes	48/708	205/7206	6.2618138211e-09
ko05032	Morphine addiction	32/708	110/7206	8.9812505185e-09
ko04721	Synaptic vesicle cycle	26/708	80/7206	1.80430504185e-08
ko04725	Cholinergic synapse	39/708	160/7206	5.08284496593e-08
ko04723	Retrograde endocannabinoid signaling	41/708	175/7206	8.6838779358e-08
ko05030	Cocaine addiction	23/708	73/7206	2.28778612482e-07
ko04514	Cell adhesion molecules (CAMs)	32/708	130/7206	6.4513321119e-07
ko05164	Influenza A	1/708	167/7206	1.00997167489e-06
ko04974	Protein digestion and absorption	26/708	96/7206	1.04261887102e-06
ko04950	Maturity onset diabetes of the young	13/708	29/7206	1.09019703439e-06
ko04024	cAMP signaling pathway	52/708	279/7206	4.4883191145e-06
ko04360	Axon guidance	45/708	233/7206	8.5939410476e-06
ko05031	Amphetamine addiction	23/708	91/7206	1.52662962722e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	21/708	79/7206	1.55359809396e-05
ko05410	Hypertrophic cardiomyopathy (HCM)	24/708	100/7206	2.55230700088e-05
ko04726	Serotonergic synapse	30/708	137/7206	2.80048464154e-05
ko04060	Cytokine-cytokine receptor interaction	4/708	191/7206	3.60367576838e-05
ko04964	Proximal tubule bicarbonate reclamation	11/708	29/7206	5.02512268019e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	19/708	74/7206	6.60114382395e-05
ko05168	Herpes simplex infection	4/708	182/7206	7.37754939009e-05
ko05162	Measles	1/708	120/7206	8.06658786692e-05
ko04120	Ubiquitin mediated proteolysis	2/708	138/7206	0.000128866425096
ko04010	MAPK signaling pathway	53/708	321/7206	0.00015731563502
ko04512	ECM-receptor interaction	19/708	79/7206	0.000169964850237
ko04976	Bile secretion	19/708	80/7206	0.000202856792394
ko04740	Olfactory transduction	19/708	80/7206	0.000202856792394
ko05414	Dilated cardiomyopathy	24/708	112/7206	0.000289100132403
ko03013	RNA transport	4/708	166/7206	0.000304035878302
ko04621	NOD-like receptor signaling pathway	4/708	157/7206	0.000607971099372
ko04742	Taste transduction	15/708	61/7206	0.000628219007645
ko05169	Epstein-Barr virus infection	7/708	206/7206	0.000762230782016
ko05203	Viral carcinogenesis	12/708	277/7206	0.00090177815422
ko00564	Glycerophospholipid metabolism	1/708	99/7206	0.000903526586293
ko04151	PI3K-Akt signaling pathway	58/708	390/7206	0.00113734021441
ko04978	Mineral absorption	11/708	40/7206	0.00122730806333
ko05322	Systemic lupus erythematosus	4/708	151/7206	0.0012436637396
ko04140	Autophagy - animal	5/708	164/7206	0.00131291228976
ko04611	Platelet activation	5/708	163/7206	0.00189886795143
ko04970	Salivary secretion	19/708	95/7206	0.00250657950227
ko04150	mTOR signaling pathway	7/708	184/7206	0.00355361875712
ko04921	Oxytocin signaling pathway	33/708	209/7206	0.00620651791507
ko04610	Complement and coagulation cascades	1/708	79/7206	0.00635676360793
ko03008	Ribosome biogenesis in eukaryotes	1/708	79/7206	0.00635676360793
ko00430	Taurine and hypotaurine metabolism	5/708	14/7206	0.00850031835099
ko04214	Apoptosis - fly	1/708	72/7206	0.00872603668428
ko00230	Purine metabolism	9/708	194/7206	0.0100722885602
ko04932	Non-alcoholic fatty liver disease (NAFLD)	8/708	182/7206	0.0109490448436
ko04914	Progesterone-mediated oocyte maturation	3/708	104/7206	0.0119055342916
ko04142	Lysosome	6/708	151/7206	0.0120712587607
ko04217	Necroptosis	8/708	178/7206	0.0145424327498
ko04972	Pancreatic secretion	19/708	111/7206	0.0148503962083
ko03018	RNA degradation	2/708	84/7206	0.0153892486472
ko05166	HTLV-I infection	17/708	292/7206	0.0159048441017
ko04540	Gap junction	21/708	128/7206	0.0161478670365
ko00600	Sphingolipid metabolism	1/708	63/7206	0.0186649384859
ko04640	Hematopoietic cell lineage	1/708	64/7206	0.0187367461117
ko05418	Fluid shear stress and atherosclerosis	8/708	173/7206	0.0190090840279
ko04022	cGMP-PKG signaling pathway	32/708	216/7206	0.0194151460421
ko04744	Phototransduction	8/708	36/7206	0.0210766522446
ko04730	Long-term depression	14/708	78/7206	0.0213886888877
ko04138	Autophagy - yeast	2/708	81/7206	0.0222211746284
ko04141	Protein processing in endoplasmic reticulum	9/708	184/7206	0.0229120984797
ko04064	NF-kappa B signaling pathway	3/708	96/7206	0.023292219241
ko04070	Phosphatidylinositol signaling system	4/708	112/7206	0.0235352610593
ko04962	Vasopressin-regulated water reabsorption	11/708	58/7206	0.0262477765345
ko04924	Renin secretion	15/708	86/7206	0.0264605925022
ko04218	Cellular senescence	9/708	177/7206	0.0292723074167
ko05140	Leishmaniasis	2/708	75/7206	0.0309351590161
ko04630	Jak-STAT signaling pathway	6/708	132/7206	0.0380091189098
ko00350	Tyrosine metabolism	7/708	33/7206	0.0380541382315
ko04971	Gastric acid secretion	16/708	98/7206	0.0386565720019
ko00520	Amino sugar and nucleotide sugar metabolism	1/708	55/7206	0.0396913251354
ko04720	Long-term potentiation	16/708	99/7206	0.040433079983
ko04961	Endocrine and other factor-regulated calcium reabsorption	11/708	59/7206	0.0431171612612
ko04113	Meiosis - yeast	2/708	70/7206	0.0436908777683
ko04146	Peroxisome	3/708	89/7206	0.0457269520664
ko05134	Legionellosis	2/708	74/7206	0.0458509621279
ko04110	Cell cycle	7/708	145/7206	0.0467261396746