ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	98/470	423/7206	6.16921696662e-31
ko05033	Nicotine addiction	36/470	56/7206	1.33876820611e-29
ko04724	Glutamatergic synapse	53/470	152/7206	7.79555258169e-26
ko04727	GABAergic synapse	35/470	110/7206	6.05552315467e-16
ko05032	Morphine addiction	35/470	110/7206	6.05552315467e-16
ko04723	Retrograde endocannabinoid signaling	44/470	175/7206	1.79693766133e-15
ko04728	Dopaminergic synapse	44/470	185/7206	1.60153207048e-14
ko04721	Synaptic vesicle cycle	27/470	80/7206	2.83425794501e-13
ko04713	Circadian entrainment	34/470	136/7206	3.93923331775e-12
ko05030	Cocaine addiction	23/470	73/7206	8.47267218231e-11
ko04024	cAMP signaling pathway	49/470	279/7206	8.87033389701e-11
ko04725	Cholinergic synapse	32/470	160/7206	7.61707931699e-09
ko05031	Amphetamine addiction	23/470	91/7206	1.03871449502e-08
ko04911	Insulin secretion	25/470	117/7206	8.95370824797e-08
ko05014	Amyotrophic lateral sclerosis (ALS)	19/470	74/7206	1.5428449589e-07
ko04726	Serotonergic synapse	25/470	137/7206	2.08156107834e-06
ko04514	Cell adhesion molecules (CAMs)	24/470	130/7206	2.6938016442e-06
ko04742	Taste transduction	15/470	61/7206	5.69196447584e-06
ko04720	Long-term potentiation	19/470	99/7206	1.67258803625e-05
ko04010	MAPK signaling pathway	41/470	321/7206	2.47107266639e-05
ko04730	Long-term depression	16/470	78/7206	3.29398160595e-05
ko04261	Adrenergic signaling in cardiomyocytes	30/470	205/7206	3.44481768859e-05
ko04921	Oxytocin signaling pathway	30/470	209/7206	4.15738004747e-05
ko04972	Pancreatic secretion	18/470	111/7206	0.000269917436913
ko04970	Salivary secretion	16/470	95/7206	0.000377327390867
ko05203	Viral carcinogenesis	5/470	277/7206	0.000417649466928
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	14/470	79/7206	0.000508922181397
ko03040	Spliceosome	1/470	145/7206	0.00100878486151
ko04120	Ubiquitin mediated proteolysis	1/470	138/7206	0.00147533377535
ko05164	Influenza A	2/470	167/7206	0.0021115839536
ko04964	Proximal tubule bicarbonate reclamation	7/470	29/7206	0.00212761309368
ko04060	Cytokine-cytokine receptor interaction	3/470	191/7206	0.00251760384264
ko04020	Calcium signaling pathway	30/470	265/7206	0.00315937215046
ko04360	Axon guidance	27/470	233/7206	0.00409396499191
ko04961	Endocrine and other factor-regulated calcium reabsorption	10/470	59/7206	0.00440369875335
ko05162	Measles	1/470	120/7206	0.00460482154277
ko04218	Cellular senescence	3/470	177/7206	0.00488416458916
ko05205	Proteoglycans in cancer	7/470	271/7206	0.00532321541328
ko04540	Gap junction	17/470	128/7206	0.00544417243438
ko04260	Cardiac muscle contraction	14/470	98/7206	0.00556691568138
ko04072	Phospholipase D signaling pathway	23/470	197/7206	0.00754076134586
ko04930	Type II diabetes mellitus	9/470	54/7206	0.00757044499365
ko00604	Glycosphingolipid biosynthesis - ganglio series	4/470	14/7206	0.0105779638778
ko04630	Jak-STAT signaling pathway	2/470	132/7206	0.0119515065761
ko04621	NOD-like receptor signaling pathway	3/470	157/7206	0.0131828005478
ko04217	Necroptosis	4/470	178/7206	0.0135035026812
ko05168	Herpes simplex infection	4/470	182/7206	0.0137881326879
ko05169	Epstein-Barr virus infection	5/470	206/7206	0.0138111150044
ko01200	Carbon metabolism	2/470	128/7206	0.0171709134271
ko05322	Systemic lupus erythematosus	3/470	151/7206	0.0183404491358
ko03013	RNA transport	4/470	166/7206	0.0251481678794
ko05166	HTLV-I infection	10/470	292/7206	0.0284757242239
ko04915	Estrogen signaling pathway	15/470	131/7206	0.0301556996809
ko04141	Protein processing in endoplasmic reticulum	5/470	184/7206	0.0328596601866
ko04015	Rap1 signaling pathway	27/470	278/7206	0.034510580576
ko04971	Gastric acid secretion	12/470	98/7206	0.0351933387038
ko04976	Bile secretion	10/470	80/7206	0.0386514220925
ko04137	Mitophagy - animal	1/470	82/7206	0.0428923238197
ko03018	RNA degradation	1/470	84/7206	0.0430914145493
ko04960	Aldosterone-regulated sodium reabsorption	6/470	41/7206	0.0480414926665
ko00240	Pyrimidine metabolism	2/470	110/7206	0.0481943133504