ko pathway ratio_in_study ratio_in_pop p_value ko04070 Phosphatidylinositol signaling system 13/141 112/7206 2.29267148819e-07 ko05231 Choline metabolism in cancer 13/141 134/7206 1.84695083784e-06 ko04724 Glutamatergic synapse 12/141 152/7206 3.85070588515e-05 ko04925 Aldosterone synthesis and secretion 9/141 105/7206 0.000198898312438 ko04727 GABAergic synapse 9/141 110/7206 0.000282956694158 ko00562 Inositol phosphate metabolism 8/141 89/7206 0.000327248921289 ko04072 Phospholipase D signaling pathway 12/141 197/7206 0.00045256450989 ko04666 Fc gamma R-mediated phagocytosis 9/141 122/7206 0.000609640335135 ko00564 Glycerophospholipid metabolism 8/141 99/7206 0.000673311137852 ko05214 Glioma 7/141 79/7206 0.000847129638674 ko05032 Morphine addiction 8/141 110/7206 0.00134580507184 ko04911 Insulin secretion 8/141 117/7206 0.00199783504946 ko04921 Oxytocin signaling pathway 11/141 209/7206 0.00254889993532 ko00010 Glycolysis / Gluconeogenesis 6/141 74/7206 0.00313704433572 ko04720 Long-term potentiation 7/141 99/7206 0.00314786494838 ko04728 Dopaminergic synapse 10/141 185/7206 0.00328613275403 ko04922 Glucagon signaling pathway 8/141 128/7206 0.0035003281915 ko04722 Neurotrophin signaling pathway 9/141 160/7206 0.00402696338448 ko04725 Cholinergic synapse 9/141 160/7206 0.00402696338448 ko05033 Nicotine addiction 5/141 56/7206 0.00458164540186 ko04012 ErbB signaling pathway 7/141 109/7206 0.00536242013498 ko01230 Biosynthesis of amino acids 6/141 85/7206 0.00621888113565 ko04261 Adrenergic signaling in cardiomyocytes 10/141 205/7206 0.00675744842162 ko02010 ABC transporters 4/141 39/7206 0.00679347835608 ko00561 Glycerolipid metabolism 5/141 63/7206 0.00756223591009 ko05031 Amphetamine addiction 6/141 91/7206 0.00861884893229 ko05223 Non-small cell lung cancer 5/141 66/7206 0.00917838621196 ko04915 Estrogen signaling pathway 7/141 131/7206 0.014107884252 ko00710 Carbon fixation in photosynthetic organisms 3/141 27/7206 0.0152153563165 ko00510 N-Glycan biosynthesis 4/141 50/7206 0.016132251921 ko00601 Glycosphingolipid biosynthesis - lacto and neolacto series 3/141 28/7206 0.0168016433692 ko04713 Circadian entrainment 7/141 136/7206 0.0170313052122 ko04020 Calcium signaling pathway 11/141 265/7206 0.0193518664336 ko04011 MAPK signaling pathway - yeast 4/141 53/7206 0.0196148770366 ko04740 Olfactory transduction 5/141 80/7206 0.0198920965721 ko00514 Other types of O-glycan biosynthesis 3/141 30/7206 0.0202420819669 ko04930 Type II diabetes mellitus 4/141 54/7206 0.0208710145054 ko05230 Central carbon metabolism in cancer 5/141 81/7206 0.0208772934055 ko04723 Retrograde endocannabinoid signaling 8/141 175/7206 0.0211823273502 ko00680 Methane metabolism 3/141 34/7206 0.0281991581386 ko04912 GnRH signaling pathway 6/141 122/7206 0.0320924552047 ko04750 Inflammatory mediator regulation of TRP channels 6/141 122/7206 0.0320924552047 ko04211 Longevity regulating pathway 6/141 123/7206 0.0332148019928 ko00533 Glycosaminoglycan biosynthesis - keratan sulfate 2/141 15/7206 0.0337905121685 ko04139 Mitophagy - yeast 3/141 37/7206 0.0351048095964 ko04745 Phototransduction - fly 3/141 38/7206 0.0375833016201 ko01200 Carbon metabolism 6/141 128/7206 0.0392085984988 ko05211 Renal cell carcinoma 5/141 96/7206 0.0395843169736 ko05142 Chagas disease (American trypanosomiasis) 6/141 130/7206 0.0417871697434 ko04971 Gastric acid secretion 5/141 98/7206 0.0426588178519 ko05146 Amoebiasis 5/141 99/7206 0.0442487352692 ko04960 Aldosterone-regulated sodium reabsorption 3/141 41/7206 0.0455398268778 ko00051 Fructose and mannose metabolism 3/141 42/7206 0.0483630767941 ko00513 Various types of N-glycan biosynthesis 3/141 42/7206 0.0483630767941 ko04973 Carbohydrate digestion and absorption 3/141 42/7206 0.0483630767941