ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	192/1229	423/7206	4.93602155814e-45
ko04724	Glutamatergic synapse	81/1229	152/7206	7.30063053015e-25
ko05033	Nicotine addiction	43/1229	56/7206	9.57740735279e-23
ko04713	Circadian entrainment	70/1229	136/7206	1.72314812797e-20
ko05032	Morphine addiction	59/1229	110/7206	1.38364408788e-18
ko04721	Synaptic vesicle cycle	48/1229	80/7206	4.8097247903e-18
ko04727	GABAergic synapse	58/1229	110/7206	8.00492213058e-18
ko04728	Dopaminergic synapse	79/1229	185/7206	9.05954389871e-17
ko04020	Calcium signaling pathway	99/1229	265/7206	6.34709172365e-16
ko04024	cAMP signaling pathway	99/1229	279/7206	3.2256291812e-14
ko04725	Cholinergic synapse	67/1229	160/7206	6.75131162601e-14
ko04723	Retrograde endocannabinoid signaling	70/1229	175/7206	4.29161331321e-13
ko04726	Serotonergic synapse	58/1229	137/7206	1.94367827547e-12
ko04921	Oxytocin signaling pathway	77/1229	209/7206	3.68974876485e-12
ko04911	Insulin secretion	51/1229	117/7206	1.14806829998e-11
ko04970	Salivary secretion	43/1229	95/7206	1.09537132772e-10
ko04742	Taste transduction	31/1229	61/7206	1.32064376417e-09
ko05031	Amphetamine addiction	40/1229	91/7206	1.44611676079e-09
ko03010	Ribosome	1/1229	129/7206	1.5694448984e-09
ko03040	Spliceosome	3/1229	145/7206	9.78174116405e-09
ko05322	Systemic lupus erythematosus	4/1229	151/7206	3.62200316804e-08
ko04022	cGMP-PKG signaling pathway	68/1229	216/7206	1.65666693828e-07
ko04744	Phototransduction	20/1229	36/7206	1.71715706974e-07
ko04925	Aldosterone synthesis and secretion	40/1229	105/7206	2.4244184038e-07
ko04966	Collecting duct acid secretion	16/1229	26/7206	4.47467107559e-07
ko04720	Long-term potentiation	38/1229	99/7206	4.69002988222e-07
ko04971	Gastric acid secretion	37/1229	98/7206	8.93685914442e-07
ko04730	Long-term depression	31/1229	78/7206	1.94986464571e-06
ko04261	Adrenergic signaling in cardiomyocytes	62/1229	205/7206	2.79866938048e-06
ko03013	RNA transport	8/1229	166/7206	2.90822300945e-06
ko04110	Cell cycle	6/1229	145/7206	3.07396656321e-06
ko05203	Viral carcinogenesis	21/1229	277/7206	4.22703823367e-06
ko04070	Phosphatidylinositol signaling system	38/1229	112/7206	1.13849435348e-05
ko05168	Herpes simplex infection	11/1229	182/7206	1.37063322033e-05
ko04972	Pancreatic secretion	37/1229	111/7206	3.12539107321e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	27/1229	74/7206	5.92673793324e-05
ko04745	Phototransduction - fly	17/1229	38/7206	6.13873211023e-05
ko05164	Influenza A	11/1229	167/7206	9.74157515534e-05
ko04964	Proximal tubule bicarbonate reclamation	14/1229	29/7206	9.94888832338e-05
ko03008	Ribosome biogenesis in eukaryotes	2/1229	79/7206	0.000112110584863
ko05030	Cocaine addiction	26/1229	73/7206	0.000115548825713
ko04141	Protein processing in endoplasmic reticulum	14/1229	184/7206	0.000220639984548
ko04740	Olfactory transduction	27/1229	80/7206	0.000249692669498
ko05110	Vibrio cholerae infection	23/1229	63/7206	0.000261003633676
ko04270	Vascular smooth muscle contraction	44/1229	154/7206	0.000309852240408
ko04014	Ras signaling pathway	71/1229	279/7206	0.000325316123251
ko04540	Gap junction	38/1229	128/7206	0.000328590028116
ko05162	Measles	7/1229	120/7206	0.000342936331828
ko04710	Circadian rhythm	17/1229	43/7206	0.000382362598601
ko04924	Renin secretion	28/1229	86/7206	0.000414893773507
ko04750	Inflammatory mediator regulation of TRP channels	36/1229	122/7206	0.000581711920736
ko05166	HTLV-I infection	29/1229	292/7206	0.000603143150713
ko00120	Primary bile acid biosynthesis	10/1229	20/7206	0.000709548438144
ko04072	Phospholipase D signaling pathway	52/1229	197/7206	0.000740609836607
ko04976	Bile secretion	26/1229	80/7206	0.000781409903726
ko04010	MAPK signaling pathway	78/1229	321/7206	0.000790605437754
ko00520	Amino sugar and nucleotide sugar metabolism	1/1229	55/7206	0.000852383865322
ko04960	Aldosterone-regulated sodium reabsorption	16/1229	41/7206	0.00112693581295
ko04371	Apelin signaling pathway	47/1229	177/7206	0.00115822267634
ko05169	Epstein-Barr virus infection	19/1229	206/7206	0.00180322702367
ko05161	Hepatitis B	15/1229	173/7206	0.00201680976596
ko04514	Cell adhesion molecules (CAMs)	36/1229	130/7206	0.00206929101636
ko05205	Proteoglycans in cancer	28/1229	271/7206	0.00221322423077
ko04120	Ubiquitin mediated proteolysis	11/1229	138/7206	0.00278220917097
ko03420	Nucleotide excision repair	1/1229	46/7206	0.00283190495895
ko05219	Bladder cancer	1/1229	48/7206	0.00298667697949
ko04612	Antigen processing and presentation	4/1229	77/7206	0.00333276370234
ko04350	TGF-beta signaling pathway	7/1229	103/7206	0.00341367042252
ko04550	Signaling pathways regulating pluripotency of stem cells	15/1229	165/7206	0.00450082690453
ko04961	Endocrine and other factor-regulated calcium reabsorption	19/1229	59/7206	0.00452281192107
ko04621	NOD-like receptor signaling pathway	14/1229	157/7206	0.00499826291245
ko04626	Plant-pathogen interaction	8/1229	18/7206	0.00610600458283
ko04622	RIG-I-like receptor signaling pathway	3/1229	62/7206	0.00624118476744
ko04260	Cardiac muscle contraction	27/1229	98/7206	0.00945024076343
ko04360	Axon guidance	55/1229	233/7206	0.00994105286517
ko04922	Glucagon signaling pathway	33/1229	128/7206	0.0121975385941
ko05212	Pancreatic cancer	6/1229	83/7206	0.0124764480327
ko04711	Circadian rhythm - fly	6/1229	13/7206	0.0140774399769
ko04060	Cytokine-cytokine receptor interaction	20/1229	191/7206	0.0143491678894
ko03410	Base excision repair	1/1229	38/7206	0.0149831200092
ko00562	Inositol phosphate metabolism	24/1229	89/7206	0.0158757837429
ko05131	Shigellosis	6/1229	82/7206	0.0171548580046
ko04214	Apoptosis - fly	5/1229	72/7206	0.0178378549094
ko04930	Type II diabetes mellitus	16/1229	54/7206	0.0182666571858
ko04915	Estrogen signaling pathway	33/1229	131/7206	0.0183118221881
ko04115	p53 signaling pathway	5/1229	74/7206	0.0184012980482
ko04217	Necroptosis	19/1229	178/7206	0.0201091651467
ko05016	Huntington's disease	24/1229	215/7206	0.0209053799278
ko04657	IL-17 signaling pathway	7/1229	87/7206	0.0214274719391
ko05133	Pertussis	7/1229	87/7206	0.0214274719391
ko05215	Prostate cancer	10/1229	111/7206	0.0215384187729
ko05145	Toxoplasmosis	12/1229	126/7206	0.0226069737318
ko04113	Meiosis - yeast	5/1229	70/7206	0.0245387263113
ko04218	Cellular senescence	19/1229	177/7206	0.0254011942087
ko04330	Notch signaling pathway	4/1229	62/7206	0.025888101543
ko04630	Jak-STAT signaling pathway	13/1229	132/7206	0.025916790347
ko05220	Chronic myeloid leukemia	7/1229	85/7206	0.02875292939
ko04620	Toll-like receptor signaling pathway	9/1229	100/7206	0.031354184598
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	21/1229	79/7206	0.0336717578893
ko05217	Basal cell carcinoma	5/1229	68/7206	0.0337784598037
ko04210	Apoptosis	20/1229	180/7206	0.0344459835411
ko05200	Pathways in cancer	67/1229	492/7206	0.0348043244979
ko05231	Choline metabolism in cancer	32/1229	134/7206	0.037193705619
ko05140	Leishmaniasis	6/1229	75/7206	0.0429662272097
ko04932	Non-alcoholic fatty liver disease (NAFLD)	21/1229	182/7206	0.0456833957445
ko04923	Regulation of lipolysis in adipocytes	20/1229	77/7206	0.0463225462261
ko04520	Adherens junction	10/1229	103/7206	0.0472480201137
ko05340	Primary immunodeficiency	1/1229	30/7206	0.0486958801888
ko05202	Transcriptional misregulation in cancer	22/1229	188/7206	0.0491804398195
ko05120	Epithelial cell signaling in Helicobacter pylori infection	23/1229	92/7206	0.0499029347347