ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	156/880	423/7206	5.4472938415e-42
ko04724	Glutamatergic synapse	83/880	152/7206	2.73495203383e-37
ko05033	Nicotine addiction	47/880	56/7206	1.01783797223e-34
ko04727	GABAergic synapse	64/880	110/7206	4.20029408544e-31
ko05032	Morphine addiction	62/880	110/7206	4.46499883025e-29
ko04723	Retrograde endocannabinoid signaling	72/880	175/7206	1.10542637791e-22
ko04713	Circadian entrainment	62/880	136/7206	1.68988127489e-22
ko04728	Dopaminergic synapse	71/880	185/7206	2.64527220133e-20
ko04725	Cholinergic synapse	63/880	160/7206	8.5707664458e-19
ko04024	cAMP signaling pathway	86/880	279/7206	2.93444389722e-17
ko04721	Synaptic vesicle cycle	39/880	80/7206	8.19238345324e-16
ko04726	Serotonergic synapse	53/880	137/7206	1.33991453322e-15
ko04744	Phototransduction	25/880	36/7206	1.72365241956e-15
ko04911	Insulin secretion	48/880	117/7206	2.02409101401e-15
ko04742	Taste transduction	33/880	61/7206	2.71761090651e-15
ko04020	Calcium signaling pathway	75/880	265/7206	5.38187086179e-13
ko04921	Oxytocin signaling pathway	61/880	209/7206	2.18912363152e-11
ko05031	Amphetamine addiction	34/880	91/7206	5.53871793582e-10
ko04261	Adrenergic signaling in cardiomyocytes	57/880	205/7206	8.21162084185e-10
ko04720	Long-term potentiation	35/880	99/7206	1.75541140604e-09
ko05030	Cocaine addiction	28/880	73/7206	9.46813873911e-09
ko05203	Viral carcinogenesis	8/880	277/7206	3.30497270891e-08
ko04970	Salivary secretion	32/880	95/7206	3.35654149731e-08
ko03040	Spliceosome	1/880	145/7206	2.28202073171e-07
ko04972	Pancreatic secretion	32/880	111/7206	2.28425132412e-06
ko04925	Aldosterone synthesis and secretion	31/880	105/7206	2.53441835995e-06
ko04010	MAPK signaling pathway	67/880	321/7206	6.94219449982e-06
ko04514	Cell adhesion molecules (CAMs)	34/880	130/7206	1.01710043385e-05
ko04022	cGMP-PKG signaling pathway	49/880	216/7206	1.15759402793e-05
ko04971	Gastric acid secretion	28/880	98/7206	1.22391478684e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	23/880	74/7206	1.32506582203e-05
ko04060	Cytokine-cytokine receptor interaction	6/880	191/7206	1.4982826035e-05
ko04740	Olfactory transduction	24/880	80/7206	1.68752214534e-05
ko04072	Phospholipase D signaling pathway	45/880	197/7206	2.16002364454e-05
ko05164	Influenza A	5/880	167/7206	3.64422252093e-05
ko04621	NOD-like receptor signaling pathway	5/880	157/7206	0.00010545068427
ko04260	Cardiac muscle contraction	26/880	98/7206	0.0001191574798
ko05169	Epstein-Barr virus infection	9/880	206/7206	0.000138325509058
ko04730	Long-term depression	22/880	78/7206	0.000142181072221
ko03013	RNA transport	6/880	166/7206	0.000166264448088
ko05322	Systemic lupus erythematosus	5/880	151/7206	0.000214794602932
ko04070	Phosphatidylinositol signaling system	27/880	112/7206	0.000391376908856
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	21/880	79/7206	0.000402899889949
ko04110	Cell cycle	5/880	145/7206	0.000437859643274
ko05168	Herpes simplex infection	8/880	182/7206	0.000497317756115
ko05205	Proteoglycans in cancer	16/880	271/7206	0.000618208406548
ko03008	Ribosome biogenesis in eukaryotes	1/880	79/7206	0.000759100892626
ko04540	Gap junction	29/880	128/7206	0.000886290591783
ko05162	Measles	4/880	120/7206	0.00106510583211
ko05414	Dilated cardiomyopathy	26/880	112/7206	0.00111222797205
ko04141	Protein processing in endoplasmic reticulum	9/880	184/7206	0.00124694664011
ko04350	TGF-beta signaling pathway	3/880	103/7206	0.0013233588126
ko04976	Bile secretion	20/880	80/7206	0.00152356327166
ko04964	Proximal tubule bicarbonate reclamation	10/880	29/7206	0.00157955149811
ko04120	Ubiquitin mediated proteolysis	6/880	138/7206	0.00232220185816
ko04915	Estrogen signaling pathway	28/880	131/7206	0.00271527783613
ko05161	Hepatitis B	9/880	173/7206	0.00301448303371
ko04064	NF-kappa B signaling pathway	3/880	96/7206	0.00403713092891
ko04924	Renin secretion	20/880	86/7206	0.00408563041493
ko04745	Phototransduction - fly	11/880	38/7206	0.00448680746619
ko04750	Inflammatory mediator regulation of TRP channels	26/880	122/7206	0.00468423939573
ko04610	Complement and coagulation cascades	2/880	79/7206	0.00485509656069
ko04014	Ras signaling pathway	50/880	279/7206	0.00491692957272
ko05140	Leishmaniasis	2/880	75/7206	0.00691033742125
ko05231	Choline metabolism in cancer	27/880	134/7206	0.00737120557441
ko04932	Non-alcoholic fatty liver disease (NAFLD)	11/880	182/7206	0.00798498699158
ko04966	Collecting duct acid secretion	8/880	26/7206	0.00994688895717
ko05206	MicroRNAs in cancer	11/880	177/7206	0.0103852811439
ko04630	Jak-STAT signaling pathway	7/880	132/7206	0.0105320730828
ko04062	Chemokine signaling pathway	37/880	201/7206	0.0114145694034
ko05034	Alcoholism	42/880	238/7206	0.0117470755308
ko00562	Inositol phosphate metabolism	19/880	89/7206	0.0134153079961
ko04360	Axon guidance	41/880	233/7206	0.0143096044473
ko05200	Pathways in cancer	43/880	492/7206	0.0150663698648
ko04140	Autophagy - animal	10/880	164/7206	0.0150694799899
ko04710	Circadian rhythm	11/880	43/7206	0.0157744730892
ko00590	Arachidonic acid metabolism	1/880	52/7206	0.0174418363812
ko04918	Thyroid hormone synthesis	18/880	86/7206	0.0192420330699
ko04371	Apelin signaling pathway	32/880	177/7206	0.0198305899158
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/880	14/7206	0.0208708405468
ko04510	Focal adhesion	18/880	240/7206	0.0209367423808
ko05130	Pathogenic Escherichia coli infection	3/880	77/7206	0.0216003291065
ko04146	Peroxisome	4/880	89/7206	0.0216307869746
ko05222	Small cell lung cancer	4/880	89/7206	0.0216307869746
ko05202	Transcriptional misregulation in cancer	13/880	188/7206	0.0234326301457
ko05219	Bladder cancer	1/880	48/7206	0.0254377751135
ko00240	Pyrimidine metabolism	6/880	110/7206	0.0268850636892
ko05215	Prostate cancer	6/880	111/7206	0.0271389271062
ko04550	Signaling pathways regulating pluripotency of stem cells	11/880	165/7206	0.0293985662858
ko05410	Hypertrophic cardiomyopathy (HCM)	20/880	100/7206	0.0294825218061
ko04330	Notch signaling pathway	2/880	62/7206	0.0295891886919
ko00310	Lysine degradation	3/880	73/7206	0.0300321689508
ko05133	Pertussis	4/880	87/7206	0.0303028161067
ko05110	Vibrio cholerae infection	14/880	63/7206	0.0304794395693
ko04973	Carbohydrate digestion and absorption	10/880	42/7206	0.0309018043386
ko04142	Lysosome	10/880	151/7206	0.0322631051767
ko05418	Fluid shear stress and atherosclerosis	12/880	173/7206	0.0334828405853
ko05016	Huntington's disease	16/880	215/7206	0.0335978943623
ko05166	HTLV-I infection	24/880	292/7206	0.0353275905035
ko03022	Basal transcription factors	1/880	44/7206	0.0372728037473
ko05144	Malaria	1/880	45/7206	0.0374942779512
ko00071	Fatty acid degradation	1/880	45/7206	0.0374942779512
ko04210	Apoptosis	13/880	180/7206	0.0375722103327
ko03420	Nucleotide excision repair	1/880	46/7206	0.0383043009245
ko05145	Toxoplasmosis	8/880	126/7206	0.0395073814231
ko03320	PPAR signaling pathway	3/880	69/7206	0.0417068038682
ko04218	Cellular senescence	13/880	177/7206	0.0474330105203