ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	76/818	152/7206	5.85767408571e-33
ko04080	Neuroactive ligand-receptor interaction	133/818	423/7206	8.3650260952e-31
ko04713	Circadian entrainment	59/818	136/7206	9.48586135606e-22
ko05033	Nicotine addiction	36/818	56/7206	3.99118465867e-21
ko04727	GABAergic synapse	49/818	110/7206	7.71945217758e-19
ko05032	Morphine addiction	49/818	110/7206	7.71945217758e-19
ko04728	Dopaminergic synapse	65/818	185/7206	4.90420179848e-18
ko04020	Calcium signaling pathway	79/818	265/7206	7.33247356687e-17
ko04723	Retrograde endocannabinoid signaling	60/818	175/7206	3.7579627314e-16
ko04726	Serotonergic synapse	50/818	137/7206	6.90903765267e-15
ko04720	Long-term potentiation	41/818	99/7206	1.30287936849e-14
ko04911	Insulin secretion	44/818	117/7206	8.75365648908e-14
ko04024	cAMP signaling pathway	75/818	279/7206	2.50026642684e-13
ko04921	Oxytocin signaling pathway	60/818	209/7206	2.90318245429e-12
ko04261	Adrenergic signaling in cardiomyocytes	59/818	205/7206	3.95777116392e-12
ko04725	Cholinergic synapse	50/818	160/7206	6.54810323741e-12
ko05031	Amphetamine addiction	35/818	91/7206	1.49822884044e-11
ko04925	Aldosterone synthesis and secretion	36/818	105/7206	3.50822548131e-10
ko04970	Salivary secretion	33/818	95/7206	1.30925238911e-09
ko04070	Phosphatidylinositol signaling system	35/818	112/7206	1.01190951242e-08
ko04971	Gastric acid secretion	31/818	98/7206	5.17458796558e-08
ko04721	Synaptic vesicle cycle	27/818	80/7206	8.38954081314e-08
ko04730	Long-term depression	26/818	78/7206	1.93348212842e-07
ko04022	cGMP-PKG signaling pathway	51/818	216/7206	2.81913079415e-07
ko04742	Taste transduction	22/818	61/7206	3.57909221685e-07
ko03040	Spliceosome	1/818	145/7206	8.59756548505e-07
ko04745	Phototransduction - fly	16/818	38/7206	1.30368149566e-06
ko05030	Cocaine addiction	23/818	73/7206	2.97146149697e-06
ko04750	Inflammatory mediator regulation of TRP channels	32/818	122/7206	3.81265877231e-06
ko03010	Ribosome	1/818	129/7206	4.253726251e-06
ko04740	Olfactory transduction	24/818	80/7206	4.77556289859e-06
ko05168	Herpes simplex infection	4/818	182/7206	7.67030284755e-06
ko04010	MAPK signaling pathway	63/818	321/7206	8.65399713519e-06
ko05322	Systemic lupus erythematosus	3/818	151/7206	2.44480510836e-05
ko04710	Circadian rhythm	15/818	43/7206	4.16208210842e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	21/818	74/7206	4.70077253198e-05
ko04072	Phospholipase D signaling pathway	42/818	197/7206	5.03160290296e-05
ko04514	Cell adhesion molecules (CAMs)	31/818	130/7206	6.0257939737e-05
ko04060	Cytokine-cytokine receptor interaction	6/818	191/7206	6.50371925836e-05
ko04960	Aldosterone-regulated sodium reabsorption	14/818	41/7206	9.78887574892e-05
ko04540	Gap junction	30/818	128/7206	9.91199265979e-05
ko04014	Ras signaling pathway	53/818	279/7206	0.000148982889974
ko04630	Jak-STAT signaling pathway	3/818	132/7206	0.000236943350775
ko04972	Pancreatic secretion	26/818	111/7206	0.000238691435124
ko04260	Cardiac muscle contraction	24/818	98/7206	0.000276598335773
ko04110	Cell cycle	4/818	145/7206	0.000281245211183
ko04744	Phototransduction	12/818	36/7206	0.000396242281029
ko04626	Plant-pathogen interaction	8/818	18/7206	0.000410673358998
ko04922	Glucagon signaling pathway	28/818	128/7206	0.000583983322705
ko05162	Measles	3/818	120/7206	0.000684178414553
ko04360	Axon guidance	43/818	233/7206	0.00106062563133
ko05214	Glioma	19/818	79/7206	0.0011280009011
ko04912	GnRH signaling pathway	26/818	122/7206	0.00130695029881
ko04141	Protein processing in endoplasmic reticulum	8/818	184/7206	0.00131475808244
ko04918	Thyroid hormone synthesis	20/818	86/7206	0.00159744853832
ko03013	RNA transport	7/818	166/7206	0.00178240442033
ko05164	Influenza A	7/818	167/7206	0.00180561792403
ko03008	Ribosome biogenesis in eukaryotes	1/818	79/7206	0.0018398194294
ko05203	Viral carcinogenesis	16/818	277/7206	0.00187423444875
ko00562	Inositol phosphate metabolism	20/818	89/7206	0.00218789269698
ko04114	Oocyte meiosis	28/818	139/7206	0.00258344027062
ko04961	Endocrine and other factor-regulated calcium reabsorption	15/818	59/7206	0.00271782388573
ko04621	NOD-like receptor signaling pathway	7/818	157/7206	0.00328825194272
ko04924	Renin secretion	19/818	86/7206	0.00340108672892
ko05169	Epstein-Barr virus infection	11/818	206/7206	0.00363142172179
ko04964	Proximal tubule bicarbonate reclamation	9/818	29/7206	0.0036586574967
ko05231	Choline metabolism in cancer	26/818	134/7206	0.00552026773113
ko04973	Carbohydrate digestion and absorption	11/818	42/7206	0.00587805066767
ko04930	Type II diabetes mellitus	13/818	54/7206	0.00768148064094
ko04371	Apelin signaling pathway	32/818	177/7206	0.00775486752854
ko04915	Estrogen signaling pathway	25/818	131/7206	0.00786303422616
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	17/818	79/7206	0.0108802445374
ko04146	Peroxisome	3/818	89/7206	0.0112390251756
ko05222	Small cell lung cancer	3/818	89/7206	0.0112390251756
ko00680	Methane metabolism	9/818	34/7206	0.0114159150486
ko04012	ErbB signaling pathway	21/818	109/7206	0.0139276511189
ko00310	Lysine degradation	2/818	73/7206	0.0146603687075
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/818	14/7206	0.0155130671037
ko04919	Thyroid hormone signaling pathway	26/818	143/7206	0.0155382069569
ko04657	IL-17 signaling pathway	3/818	87/7206	0.0159628520799
ko04270	Vascular smooth muscle contraction	27/818	154/7206	0.0200841496541
ko00240	Pyrimidine metabolism	5/818	110/7206	0.0218241581266
ko05230	Central carbon metabolism in cancer	16/818	81/7206	0.0219149322569
ko04916	Melanogenesis	25/818	142/7206	0.0226851306655
ko05414	Dilated cardiomyopathy	21/818	112/7206	0.0227154883891
ko05132	Salmonella infection	4/818	98/7206	0.0229916297325
ko04932	Non-alcoholic fatty liver disease (NAFLD)	11/818	182/7206	0.0235943231226
ko00010	Glycolysis / Gluconeogenesis	15/818	74/7206	0.0246955916994
ko05200	Pathways in cancer	41/818	492/7206	0.0271764985184
ko04610	Complement and coagulation cascades	3/818	79/7206	0.0308776216299
ko05010	Alzheimer's disease	33/818	202/7206	0.0316553458914
ko01230	Biosynthesis of amino acids	16/818	85/7206	0.0375788521422
ko04120	Ubiquitin mediated proteolysis	8/818	138/7206	0.0407719187704
ko04330	Notch signaling pathway	2/818	62/7206	0.0423179518825
ko04622	RIG-I-like receptor signaling pathway	2/818	62/7206	0.0423179518825
ko05140	Leishmaniasis	3/818	75/7206	0.0427495958454
ko05130	Pathogenic Escherichia coli infection	3/818	77/7206	0.0440533841345
ko04640	Hematopoietic cell lineage	2/818	64/7206	0.0441150666831
ko05034	Alcoholism	37/818	238/7206	0.0474848930178