ko pathway ratio_in_study ratio_in_pop p_value ko03030 DNA replication 14/243 38/7206 7.97104725668e-12 ko03040 Spliceosome 24/243 145/7206 6.49271257301e-11 ko04110 Cell cycle 22/243 145/7206 2.34750325091e-09 ko03008 Ribosome biogenesis in eukaryotes 14/243 79/7206 2.98055428439e-07 ko04080 Neuroactive ligand-receptor interaction 1/243 423/7206 9.83754734761e-06 ko05217 Basal cell carcinoma 11/243 68/7206 1.43099174068e-05 ko03410 Base excision repair 8/243 38/7206 3.03094099854e-05 ko04111 Cell cycle - yeast 12/243 90/7206 4.36913413076e-05 ko03430 Mismatch repair 6/243 22/7206 6.54732944445e-05 ko00240 Pyrimidine metabolism 13/243 110/7206 7.63067431992e-05 ko03015 mRNA surveillance pathway 11/243 93/7206 0.000270512623506 ko04113 Meiosis - yeast 9/243 70/7206 0.00052444229166 ko03420 Nucleotide excision repair 7/243 46/7206 0.000790675182053 ko04390 Hippo signaling pathway 15/243 188/7206 0.0016492111302 ko05224 Breast cancer 14/243 174/7206 0.0021633865102 ko04350 TGF-beta signaling pathway 10/243 103/7206 0.00237570266411 ko04020 Calcium signaling pathway 1/243 265/7206 0.00249521810134 ko05205 Proteoglycans in cancer 19/243 271/7206 0.00276008376845 ko04340 Hedgehog signaling pathway 7/243 58/7206 0.00315255569485 ko04550 Signaling pathways regulating pluripotency of stem cells 13/243 165/7206 0.0037021856414 ko03013 RNA transport 13/243 166/7206 0.00389913440736 ko04612 Antigen processing and presentation 8/243 77/7206 0.00420806881381 ko04310 Wnt signaling pathway 14/243 181/7206 0.00497119177659 ko04144 Endocytosis 3/243 342/7206 0.00507883004526 ko03460 Fanconi anemia pathway 6/243 51/7206 0.00698650003584 ko05222 Small cell lung cancer 8/243 89/7206 0.0100080297192 ko00230 Purine metabolism 13/243 194/7206 0.0150260526916 ko04062 Chemokine signaling pathway 1/243 201/7206 0.0153889243359 ko03020 RNA polymerase 4/243 29/7206 0.015438585178 ko04330 Notch signaling pathway 6/243 62/7206 0.0175693603509 ko05200 Pathways in cancer 26/243 492/7206 0.019510183529 ko04141 Protein processing in endoplasmic reticulum 1/243 184/7206 0.0218309655993 ko04723 Retrograde endocannabinoid signaling 1/243 175/7206 0.0316563583524 ko04371 Apelin signaling pathway 1/243 177/7206 0.0319647710992 ko04932 Non-alcoholic fatty liver disease (NAFLD) 1/243 182/7206 0.033333653081 ko04022 cGMP-PKG signaling pathway 2/243 216/7206 0.0351508190911 ko04725 Cholinergic synapse 1/243 160/7206 0.0451925364677 ko05166 HTLV-I infection 16/243 292/7206 0.0470865275229 ko04261 Adrenergic signaling in cardiomyocytes 2/243 205/7206 0.0490704102617