ko pathway ratio_in_study ratio_in_pop p_value ko03030 DNA replication 19/257 38/7206 3.09843003016e-18 ko03410 Base excision repair 14/257 38/7206 1.70524381953e-11 ko04110 Cell cycle 24/257 145/7206 2.10596485574e-10 ko04111 Cell cycle - yeast 14/257 90/7206 3.02019350823e-06 ko03040 Spliceosome 18/257 145/7206 3.44272917532e-06 ko03430 Mismatch repair 7/257 22/7206 7.28652285599e-06 ko03420 Nucleotide excision repair 9/257 46/7206 2.80971289529e-05 ko00240 Pyrimidine metabolism 14/257 110/7206 3.24211722453e-05 ko04113 Meiosis - yeast 10/257 70/7206 0.000167769346352 ko05206 MicroRNAs in cancer 17/257 177/7206 0.00017932387059 ko04218 Cellular senescence 17/257 177/7206 0.00017932387059 ko04020 Calcium signaling pathway 1/257 265/7206 0.0010907636656 ko05217 Basal cell carcinoma 8/257 68/7206 0.00271975807477 ko04950 Maturity onset diabetes of the young 5/257 29/7206 0.00326424865189 ko05222 Small cell lung cancer 9/257 89/7206 0.00426905060334 ko00670 One carbon pool by folate 4/257 20/7206 0.0048758115537 ko03460 Fanconi anemia pathway 6/257 51/7206 0.00910211594458 ko00230 Purine metabolism 14/257 194/7206 0.0101096861267 ko04144 Endocytosis 4/257 342/7206 0.0102608499957 ko05168 Herpes simplex infection 13/257 182/7206 0.0142532620746 ko04060 Cytokine-cytokine receptor interaction 1/257 191/7206 0.0154751860769 ko04115 p53 signaling pathway 7/257 74/7206 0.0159161156753 ko04340 Hedgehog signaling pathway 6/257 58/7206 0.0166499739505 ko04612 Antigen processing and presentation 7/257 77/7206 0.0194490150881 ko04723 Retrograde endocannabinoid signaling 1/257 175/7206 0.021821492506 ko05166 HTLV-I infection 18/257 292/7206 0.0224602401803 ko04330 Notch signaling pathway 6/257 62/7206 0.0224927625161 ko04932 Non-alcoholic fatty liver disease (NAFLD) 1/257 182/7206 0.0227979594165 ko05205 Proteoglycans in cancer 16/257 271/7206 0.0434418361956 ko04341 Hedgehog signaling pathway - fly 4/257 38/7206 0.0451503466271 ko00480 Glutathione metabolism 5/257 55/7206 0.0453834230333 ko05012 Parkinson's disease 1/257 155/7206 0.0455768199035 ko04725 Cholinergic synapse 1/257 160/7206 0.0473321918021