ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 38/327 191/7206 3.91123993754e-15 ko05164 Influenza A 32/327 167/7206 1.97045851712e-12 ko04650 Natural killer cell mediated cytotoxicity 24/327 97/7206 4.28470368957e-12 ko05340 Primary immunodeficiency 13/327 30/7206 1.62890687924e-10 ko04380 Osteoclast differentiation 26/327 134/7206 1.93279413135e-10 ko05140 Leishmaniasis 19/327 75/7206 5.0734619294e-10 ko05162 Measles 24/327 120/7206 5.16634591064e-10 ko04659 Th17 cell differentiation 22/327 106/7206 1.3300966162e-09 ko04621 NOD-like receptor signaling pathway 27/327 157/7206 1.46289201892e-09 ko04217 Necroptosis 28/327 178/7206 5.78192751642e-09 ko05168 Herpes simplex infection 28/327 182/7206 9.61208463364e-09 ko05320 Autoimmune thyroid disease 11/327 29/7206 2.36136728803e-08 ko05330 Allograft rejection 10/327 24/7206 3.59174289057e-08 ko05145 Toxoplasmosis 22/327 126/7206 3.85441520372e-08 ko05321 Inflammatory bowel disease (IBD) 14/327 56/7206 1.22303919146e-07 ko04658 Th1 and Th2 cell differentiation 18/327 96/7206 2.25551109606e-07 ko04612 Antigen processing and presentation 16/327 77/7206 2.45883186555e-07 ko05152 Tuberculosis 26/327 187/7206 2.68264602688e-07 ko04620 Toll-like receptor signaling pathway 18/327 100/7206 4.2824093403e-07 ko05332 Graft-versus-host disease 8/327 18/7206 4.85145651342e-07 ko04064 NF-kappa B signaling pathway 17/327 96/7206 1.14573398662e-06 ko04630 Jak-STAT signaling pathway 20/327 132/7206 1.71879659946e-06 ko04672 Intestinal immune network for IgA production 10/327 37/7206 3.75972948959e-06 ko05167 Kaposi's sarcoma-associated herpesvirus infection 24/327 191/7206 4.91002339897e-06 ko04660 T cell receptor signaling pathway 18/327 124/7206 1.05807856372e-05 ko04062 Chemokine signaling pathway 24/327 201/7206 1.19164185372e-05 ko04640 Hematopoietic cell lineage 12/327 64/7206 2.43113717827e-05 ko04940 Type I diabetes mellitus 8/327 32/7206 6.66994956604e-05 ko05310 Asthma 6/327 17/7206 6.74718407867e-05 ko04622 RIG-I-like receptor signaling pathway 11/327 62/7206 9.02371250129e-05 ko04145 Phagosome 19/327 162/7206 0.000124847112285 ko05133 Pertussis 13/327 87/7206 0.000133324736228 ko05150 Staphylococcus aureus infection 8/327 36/7206 0.000163690765428 ko05161 Hepatitis B 19/327 173/7206 0.000296437066633 ko05034 Alcoholism 1/327 238/7206 0.000352030347091 ko04662 B cell receptor signaling pathway 12/327 88/7206 0.000571171903435 ko03050 Proteasome 9/327 54/7206 0.000637248079745 ko05142 Chagas disease (American trypanosomiasis) 15/327 130/7206 0.00075942626558 ko05144 Malaria 8/327 45/7206 0.000816433152347 ko00590 Arachidonic acid metabolism 8/327 52/7206 0.00216292223921 ko05323 Rheumatoid arthritis 11/327 89/7206 0.00217407043248 ko04623 Cytosolic DNA-sensing pathway 7/327 41/7206 0.00220230489921 ko05160 Hepatitis C 16/327 153/7206 0.00224955233269 ko04664 Fc epsilon RI signaling pathway 10/327 77/7206 0.00235966106055 ko05416 Viral myocarditis 8/327 55/7206 0.00311021400524 ko04611 Platelet activation 16/327 163/7206 0.00333812297216 ko04310 Wnt signaling pathway 1/327 181/7206 0.00335102292549 ko04670 Leukocyte transendothelial migration 15/327 151/7206 0.00426026076051 ko03013 RNA transport 1/327 166/7206 0.0071603337424 ko04080 Neuroactive ligand-receptor interaction 9/327 423/7206 0.0110117621889 ko00120 Primary bile acid biosynthesis 4/327 20/7206 0.0113261398488 ko04137 Mitophagy - animal 9/327 82/7206 0.0115746769644 ko04666 Fc gamma R-mediated phagocytosis 12/327 122/7206 0.0124189137871 ko04390 Hippo signaling pathway 2/327 188/7206 0.0124885879079 ko05146 Amoebiasis 10/327 99/7206 0.0139544637296 ko03040 Spliceosome 1/327 145/7206 0.0148718459682 ko04917 Prolactin signaling pathway 9/327 87/7206 0.0166462728409 ko04514 Cell adhesion molecules (CAMs) 12/327 130/7206 0.0169469989477 ko04728 Dopaminergic synapse 2/327 185/7206 0.0180566312534 ko04723 Retrograde endocannabinoid signaling 2/327 175/7206 0.0251952136399 ko05206 MicroRNAs in cancer 2/327 177/7206 0.0256382261351 ko04610 Complement and coagulation cascades 8/327 79/7206 0.0261599563729 ko00511 Other glycan degradation 4/327 26/7206 0.0282492159753 ko03010 Ribosome 1/327 129/7206 0.0310382395119 ko04360 Axon guidance 4/327 233/7206 0.0355614222614 ko05418 Fluid shear stress and atherosclerosis 14/327 173/7206 0.038367943191 ko05169 Epstein-Barr virus infection 16/327 206/7206 0.0385862489296 ko00051 Fructose and mannose metabolism 5/327 42/7206 0.0401216993626 ko05132 Salmonella infection 9/327 98/7206 0.0434514233335 ko04210 Apoptosis 14/327 180/7206 0.0440220308984 ko04724 Glutamatergic synapse 2/327 152/7206 0.0485537999044