ko pathway ratio_in_study ratio_in_pop p_value ko05164 Influenza A 23/168 167/7206 3.75959170496e-12 ko05168 Herpes simplex infection 21/168 182/7206 1.02199877269e-09 ko05140 Leishmaniasis 14/168 75/7206 1.32930321281e-09 ko05162 Measles 17/168 120/7206 1.8762345103e-09 ko05145 Toxoplasmosis 17/168 126/7206 4.04320688022e-09 ko05150 Staphylococcus aureus infection 10/168 36/7206 5.46888608594e-09 ko05152 Tuberculosis 20/168 187/7206 9.97677047674e-09 ko04060 Cytokine-cytokine receptor interaction 20/168 191/7206 1.43839243091e-08 ko05340 Primary immunodeficiency 9/168 30/7206 1.54373852705e-08 ko04612 Antigen processing and presentation 13/168 77/7206 1.90087468506e-08 ko04621 NOD-like receptor signaling pathway 18/168 157/7206 1.92726193546e-08 ko05321 Inflammatory bowel disease (IBD) 11/168 56/7206 4.78695835604e-08 ko04672 Intestinal immune network for IgA production 9/168 37/7206 1.16661560593e-07 ko05330 Allograft rejection 7/168 24/7206 8.18662461129e-07 ko04659 Th17 cell differentiation 13/168 106/7206 9.15552821034e-07 ko04658 Th1 and Th2 cell differentiation 12/168 96/7206 1.98991795519e-06 ko05320 Autoimmune thyroid disease 7/168 29/7206 3.34576117428e-06 ko04217 Necroptosis 16/168 178/7206 3.41569553579e-06 ko04064 NF-kappa B signaling pathway 11/168 96/7206 1.2655387501e-05 ko04380 Osteoclast differentiation 13/168 134/7206 1.29115657313e-05 ko04610 Complement and coagulation cascades 10/168 79/7206 1.30561385824e-05 ko04650 Natural killer cell mediated cytotoxicity 11/168 97/7206 1.39894520469e-05 ko04620 Toll-like receptor signaling pathway 11/168 100/7206 1.87512045019e-05 ko04145 Phagosome 14/168 162/7206 2.24906721693e-05 ko05310 Asthma 5/168 17/7206 3.19993013325e-05 ko05416 Viral myocarditis 8/168 55/7206 3.53683756069e-05 ko05167 Kaposi's sarcoma-associated herpesvirus infection 15/168 191/7206 3.54613847733e-05 ko05332 Graft-versus-host disease 5/168 18/7206 4.34754166833e-05 ko05161 Hepatitis B 14/168 173/7206 4.68965568783e-05 ko05323 Rheumatoid arthritis 9/168 89/7206 0.000210971841402 ko05160 Hepatitis C 12/168 153/7206 0.000222496479774 ko04611 Platelet activation 12/168 163/7206 0.000399816992915 ko04622 RIG-I-like receptor signaling pathway 7/168 62/7206 0.000552199941814 ko04660 T cell receptor signaling pathway 10/168 124/7206 0.000600457021425 ko04640 Hematopoietic cell lineage 7/168 64/7206 0.000670826750336 ko04940 Type I diabetes mellitus 5/168 32/7206 0.000784553775966 ko04514 Cell adhesion molecules (CAMs) 10/168 130/7206 0.000869599618725 ko04630 Jak-STAT signaling pathway 10/168 132/7206 0.000978773948753 ko03050 Proteasome 6/168 54/7206 0.00150158812956 ko04623 Cytosolic DNA-sensing pathway 5/168 41/7206 0.0024659568557 ko04670 Leukocyte transendothelial migration 10/168 151/7206 0.00269006680493 ko05144 Malaria 5/168 45/7206 0.00373056036714 ko05133 Pertussis 7/168 87/7206 0.0040354011104 ko04662 B cell receptor signaling pathway 7/168 88/7206 0.00430005893104 ko04062 Chemokine signaling pathway 11/168 201/7206 0.00716826639126 ko04664 Fc epsilon RI signaling pathway 6/168 77/7206 0.00888894466218 ko00120 Primary bile acid biosynthesis 3/168 20/7206 0.0106000393498 ko05142 Chagas disease (American trypanosomiasis) 8/168 130/7206 0.0107992005811 ko05418 Fluid shear stress and atherosclerosis 9/168 173/7206 0.0195490755561 ko04668 TNF signaling pathway 7/168 120/7206 0.0217588992429 ko05322 Systemic lupus erythematosus 8/168 151/7206 0.0245500319522 ko05134 Legionellosis 5/168 74/7206 0.0287446251655 ko05169 Epstein-Barr virus infection 10/168 206/7206 0.0291666250746 ko00590 Arachidonic acid metabolism 4/168 52/7206 0.032430441871 ko05131 Shigellosis 5/168 82/7206 0.0420534355312 ko05166 HTLV-I infection 12/168 292/7206 0.0470746129415