ko pathway ratio_in_study ratio_in_pop p_value ko05164 Influenza A 24/115 167/7206 6.3005834904e-17 ko05162 Measles 18/115 120/7206 3.28950740365e-13 ko04621 NOD-like receptor signaling pathway 20/115 157/7206 3.41587913321e-13 ko05340 Primary immunodeficiency 11/115 30/7206 4.46001499582e-13 ko05168 Herpes simplex infection 21/115 182/7206 5.98072997325e-13 ko05145 Toxoplasmosis 17/115 126/7206 9.27518426049e-12 ko04612 Antigen processing and presentation 14/115 77/7206 1.12742449939e-11 ko05161 Hepatitis B 17/115 173/7206 1.50690198575e-09 ko05140 Leishmaniasis 12/115 75/7206 1.71605235589e-09 ko04672 Intestinal immune network for IgA production 9/115 37/7206 4.19144067902e-09 ko05152 Tuberculosis 17/115 187/7206 5.01120625899e-09 ko04659 Th17 cell differentiation 13/115 106/7206 1.00663955866e-08 ko05321 Inflammatory bowel disease (IBD) 10/115 56/7206 1.38873242354e-08 ko04658 Th1 and Th2 cell differentiation 12/115 96/7206 3.10041769476e-08 ko04064 NF-kappa B signaling pathway 12/115 96/7206 3.10041769476e-08 ko04622 RIG-I-like receptor signaling pathway 10/115 62/7206 3.87039996193e-08 ko04060 Cytokine-cytokine receptor interaction 16/115 191/7206 4.75528974753e-08 ko05330 Allograft rejection 7/115 24/7206 6.0697164778e-08 ko04623 Cytosolic DNA-sensing pathway 8/115 41/7206 2.02923158919e-07 ko05320 Autoimmune thyroid disease 7/115 29/7206 2.56248551756e-07 ko04620 Toll-like receptor signaling pathway 11/115 100/7206 4.53913981397e-07 ko04217 Necroptosis 14/115 178/7206 7.62879249597e-07 ko05167 Kaposi's sarcoma-associated herpesvirus infection 14/115 191/7206 1.78511042331e-06 ko05310 Asthma 5/115 17/7206 5.0376785495e-06 ko05332 Graft-versus-host disease 5/115 18/7206 6.88672713555e-06 ko04380 Osteoclast differentiation 11/115 134/7206 8.3615074982e-06 ko04062 Chemokine signaling pathway 13/115 201/7206 1.68050999195e-05 ko04660 T cell receptor signaling pathway 10/115 124/7206 2.56607295809e-05 ko05160 Hepatitis C 11/115 153/7206 2.94221820654e-05 ko04940 Type I diabetes mellitus 5/115 32/7206 0.000135408208436 ko03050 Proteasome 6/115 54/7206 0.000200549901006 ko04630 Jak-STAT signaling pathway 9/115 132/7206 0.000241181512957 ko04145 Phagosome 10/115 162/7206 0.000244722165252 ko05133 Pertussis 7/115 87/7206 0.000447630328213 ko04640 Hematopoietic cell lineage 6/115 64/7206 0.000511515192773 ko04650 Natural killer cell mediated cytotoxicity 7/115 97/7206 0.000863389955472 ko05142 Chagas disease (American trypanosomiasis) 8/115 130/7206 0.00106197598941 ko05169 Epstein-Barr virus infection 10/115 206/7206 0.00160040910777 ko05416 Viral myocarditis 5/115 55/7206 0.00174752884775 ko05166 HTLV-I infection 12/115 292/7206 0.00230075392602 ko05150 Staphylococcus aureus infection 4/115 36/7206 0.00244540586746 ko05323 Rheumatoid arthritis 6/115 89/7206 0.00287224261434 ko04668 TNF signaling pathway 7/115 120/7206 0.00296134454335 ko05203 Viral carcinogenesis 11/115 277/7206 0.00454246885212 ko04514 Cell adhesion molecules (CAMs) 7/115 130/7206 0.00461694356357 ko05144 Malaria 4/115 45/7206 0.00554168066966 ko05134 Legionellosis 5/115 74/7206 0.00636996073229 ko04210 Apoptosis 8/115 180/7206 0.00791044358279 ko05131 Shigellosis 5/115 82/7206 0.00975990296359 ko04666 Fc gamma R-mediated phagocytosis 6/115 122/7206 0.013093616612 ko00051 Fructose and mannose metabolism 3/115 42/7206 0.028954852184 ko05215 Prostate cancer 5/115 111/7206 0.0319488233435 ko04624 Toll and Imd signaling pathway 3/115 49/7206 0.0429138681744 ko04917 Prolactin signaling pathway 4/115 87/7206 0.0499011476117