ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 25/147 191/7206 5.52415818891e-14 ko05164 Influenza A 20/147 167/7206 1.19859210539e-10 ko04621 NOD-like receptor signaling pathway 17/147 157/7206 1.55038697013e-08 ko04672 Intestinal immune network for IgA production 9/147 37/7206 3.66117697597e-08 ko04064 NF-kappa B signaling pathway 13/147 96/7206 5.87023195605e-08 ko05152 Tuberculosis 17/147 187/7206 2.08520427636e-07 ko05145 Toxoplasmosis 14/147 126/7206 2.25435043591e-07 ko04380 Osteoclast differentiation 14/147 134/7206 4.86026212919e-07 ko05162 Measles 13/147 120/7206 8.37031484468e-07 ko05340 Primary immunodeficiency 7/147 30/7206 1.75086520556e-06 ko04217 Necroptosis 15/147 178/7206 2.96425682762e-06 ko04612 Antigen processing and presentation 10/147 77/7206 3.13125384824e-06 ko04658 Th1 and Th2 cell differentiation 11/147 96/7206 3.49136587495e-06 ko04650 Natural killer cell mediated cytotoxicity 11/147 97/7206 3.86976724152e-06 ko05168 Herpes simplex infection 15/147 182/7206 3.91060211278e-06 ko04668 TNF signaling pathway 12/147 120/7206 5.27159467465e-06 ko05330 Allograft rejection 6/147 24/7206 6.46751238858e-06 ko04660 T cell receptor signaling pathway 12/147 124/7206 7.42461513698e-06 ko05161 Hepatitis B 14/147 173/7206 1.0330812656e-05 ko05323 Rheumatoid arthritis 10/147 89/7206 1.17776907166e-05 ko04630 Jak-STAT signaling pathway 12/147 132/7206 1.41467388825e-05 ko05321 Inflammatory bowel disease (IBD) 8/147 56/7206 1.53783220184e-05 ko05320 Autoimmune thyroid disease 6/147 29/7206 2.09817318446e-05 ko04620 Toll-like receptor signaling pathway 10/147 100/7206 3.31088622226e-05 ko05167 Kaposi's sarcoma-associated herpesvirus infection 13/147 191/7206 0.000131351342185 ko05140 Leishmaniasis 8/147 75/7206 0.000131731588379 ko04062 Chemokine signaling pathway 13/147 201/7206 0.000218663601259 ko04622 RIG-I-like receptor signaling pathway 7/147 62/7206 0.000245118858167 ko05160 Hepatitis C 11/147 153/7206 0.000273147896521 ko04659 Th17 cell differentiation 9/147 106/7206 0.00029232325578 ko05310 Asthma 4/147 17/7206 0.000321715117624 ko05332 Graft-versus-host disease 4/147 18/7206 0.000407112358452 ko03050 Proteasome 6/147 54/7206 0.000750051072377 ko05416 Viral myocarditis 6/147 55/7206 0.000827943623176 ko04210 Apoptosis 11/147 180/7206 0.00107932827876 ko04623 Cytosolic DNA-sensing pathway 5/147 41/7206 0.00136855784285 ko00051 Fructose and mannose metabolism 5/147 42/7206 0.00152833033589 ko05133 Pertussis 7/147 87/7206 0.00190661566042 ko05144 Malaria 5/147 45/7206 0.00209016693542 ko05166 HTLV-I infection 14/147 292/7206 0.00244929556405 ko04940 Type I diabetes mellitus 4/147 32/7206 0.00383384526547 ko04610 Complement and coagulation cascades 6/147 79/7206 0.00532458683132 ko05150 Staphylococcus aureus infection 4/147 36/7206 0.00589718539161 ko04917 Prolactin signaling pathway 6/147 87/7206 0.00847368131234 ko05146 Amoebiasis 6/147 99/7206 0.0154271214319 ko05142 Chagas disease (American trypanosomiasis) 7/147 130/7206 0.0167371539469 ko04514 Cell adhesion molecules (CAMs) 7/147 130/7206 0.0167371539469 ko04145 Phagosome 8/147 162/7206 0.0174983700239 ko05215 Prostate cancer 6/147 111/7206 0.0256007340384 ko04657 IL-17 signaling pathway 5/147 87/7206 0.0320866927099 ko04662 B cell receptor signaling pathway 5/147 88/7206 0.0334807897937 ko05120 Epithelial cell signaling in Helicobacter pylori infection 5/147 92/7206 0.0394316426995 ko04640 Hematopoietic cell lineage 4/147 64/7206 0.0411492812522