ko pathway ratio_in_study ratio_in_pop p_value ko05133 Pertussis 13/164 87/7206 6.49372127079e-08 ko05164 Influenza A 17/164 167/7206 1.99345230733e-07 ko04621 NOD-like receptor signaling pathway 16/164 157/7206 4.58217424417e-07 ko05152 Tuberculosis 17/164 187/7206 1.00952430365e-06 ko05150 Staphylococcus aureus infection 8/164 36/7206 1.06738514415e-06 ko04060 Cytokine-cytokine receptor interaction 17/164 191/7206 1.35890761253e-06 ko04630 Jak-STAT signaling pathway 14/164 132/7206 1.5341232592e-06 ko04620 Toll-like receptor signaling pathway 12/164 100/7206 2.39544574166e-06 ko05162 Measles 13/164 120/7206 2.90042803409e-06 ko05340 Primary immunodeficiency 7/164 30/7206 3.64460134149e-06 ko04660 T cell receptor signaling pathway 13/164 124/7206 4.19885517565e-06 ko04380 Osteoclast differentiation 13/164 134/7206 9.93652549936e-06 ko04650 Natural killer cell mediated cytotoxicity 11/164 97/7206 1.11253520372e-05 ko04623 Cytosolic DNA-sensing pathway 7/164 41/7206 3.26011903557e-05 ko05140 Leishmaniasis 9/164 75/7206 4.56112515628e-05 ko04622 RIG-I-like receptor signaling pathway 8/164 62/7206 7.21296475911e-05 ko05145 Toxoplasmosis 11/164 126/7206 0.000128657535956 ko05168 Herpes simplex infection 13/164 182/7206 0.000243069011535 ko04145 Phagosome 12/164 162/7206 0.000302768658947 ko04612 Antigen processing and presentation 8/164 77/7206 0.000336198575878 ko05132 Salmonella infection 9/164 98/7206 0.000365646588313 ko05160 Hepatitis C 11/164 153/7206 0.00069610999937 ko04672 Intestinal immune network for IgA production 5/164 37/7206 0.00138895883712 ko05321 Inflammatory bowel disease (IBD) 6/164 56/7206 0.001606475411 ko04664 Fc epsilon RI signaling pathway 7/164 77/7206 0.00175667196301 ko05161 Hepatitis B 11/164 173/7206 0.00190011022536 ko05330 Allograft rejection 4/164 24/7206 0.00192552584862 ko04610 Complement and coagulation cascades 7/164 79/7206 0.00203874232492 ko04217 Necroptosis 11/164 178/7206 0.00237996468479 ko05320 Autoimmune thyroid disease 4/164 29/7206 0.0039400716223 ko05167 Kaposi's sarcoma-associated herpesvirus infection 11/164 191/7206 0.00410002703568 ko04668 TNF signaling pathway 8/164 120/7206 0.0058907999109 ko04658 Th1 and Th2 cell differentiation 7/164 96/7206 0.00607985924493 ko04064 NF-kappa B signaling pathway 7/164 96/7206 0.00607985924493 ko05310 Asthma 3/164 17/7206 0.0062239737212 ko04666 Fc gamma R-mediated phagocytosis 8/164 122/7206 0.00649806971335 ko05169 Epstein-Barr virus infection 11/164 206/7206 0.00718896154049 ko01524 Platinum drug resistance 6/164 76/7206 0.00745491158044 ko04210 Apoptosis 10/164 180/7206 0.00782945761277 ko05142 Chagas disease (American trypanosomiasis) 8/164 130/7206 0.00941282826041 ko04659 Th17 cell differentiation 7/164 106/7206 0.0102989622833 ko05131 Shigellosis 6/164 82/7206 0.0106852438898 ko00051 Fructose and mannose metabolism 4/164 42/7206 0.0147812554506 ko04662 B cell receptor signaling pathway 6/164 88/7206 0.0148028984944 ko05144 Malaria 4/164 45/7206 0.0186732370819 ko04142 Lysosome 8/164 151/7206 0.0216076767127 ko04670 Leukocyte transendothelial migration 8/164 151/7206 0.0216076767127 ko00966 Glucosinolate biosynthesis 1/164 1/7206 0.022758812101 ko04020 Calcium signaling pathway 1/164 265/7206 0.0322809135374 ko03050 Proteasome 4/164 54/7206 0.0339049082826 ko05416 Viral myocarditis 4/164 55/7206 0.0359377876141 ko04917 Prolactin signaling pathway 5/164 87/7206 0.0477436066934