ko pathway ratio_in_study ratio_in_pop p_value ko04974 Protein digestion and absorption 21/423 96/7206 1.09833974035e-07 ko00350 Tyrosine metabolism 11/423 33/7206 1.49502308105e-06 ko04610 Complement and coagulation cascades 17/423 79/7206 2.30957205101e-06 ko00140 Steroid hormone biosynthesis 12/423 41/7206 2.38111218214e-06 ko00643 Styrene degradation 4/423 4/7206 1.17157161964e-05 ko00983 Drug metabolism - other enzymes 11/423 42/7206 2.04330426076e-05 ko04976 Bile secretion 15/423 80/7206 5.15450692382e-05 ko00380 Tryptophan metabolism 11/423 50/7206 0.000116395269778 ko00360 Phenylalanine metabolism 6/423 17/7206 0.000280477752904 ko00830 Retinol metabolism 9/423 42/7206 0.000597214748019 ko05034 Alcoholism 3/423 238/7206 0.000624494357283 ko00120 Primary bile acid biosynthesis 6/423 20/7206 0.000755447453627 ko00960 Tropane, piperidine and pyridine alkaloid biosynthesis 3/423 4/7206 0.000768550982479 ko05150 Staphylococcus aureus infection 8/423 36/7206 0.000929969620001 ko05134 Legionellosis 12/423 74/7206 0.00113166004649 ko00053 Ascorbate and aldarate metabolism 6/423 22/7206 0.00131551697082 ko02010 ABC transporters 8/423 39/7206 0.00161961820109 ko00950 Isoquinoline alkaloid biosynthesis 4/423 10/7206 0.00185103898396 ko03320 PPAR signaling pathway 11/423 69/7206 0.00207589853777 ko04060 Cytokine-cytokine receptor interaction 22/423 191/7206 0.0024787801269 ko04614 Renin-angiotensin system 5/423 18/7206 0.00308229669442 ko04972 Pancreatic secretion 15/423 111/7206 0.00313367730994 ko04114 Oocyte meiosis 1/423 139/7206 0.00323068632512 ko00040 Pentose and glucuronate interconversions 6/423 26/7206 0.00332415073092 ko03040 Spliceosome 1/423 145/7206 0.00341870610951 ko00362 Benzoate degradation 3/423 6/7206 0.00351542538413 ko04120 Ubiquitin mediated proteolysis 1/423 138/7206 0.00495685185096 ko04146 Peroxisome 12/423 89/7206 0.00552807762066 ko00100 Steroid biosynthesis 5/423 21/7206 0.00632807795939 ko04978 Mineral absorption 7/423 40/7206 0.00788805972167 ko00330 Arginine and proline metabolism 9/423 61/7206 0.00866092315009 ko04611 Platelet activation 18/423 163/7206 0.0099763932167 ko00561 Glycerolipid metabolism 9/423 63/7206 0.010662902965 ko04710 Circadian rhythm 7/423 43/7206 0.0117240934597 ko04640 Hematopoietic cell lineage 9/423 64/7206 0.011785384411 ko04630 Jak-STAT signaling pathway 15/423 132/7206 0.0131819150718 ko04723 Retrograde endocannabinoid signaling 3/423 175/7206 0.0134386515831 ko00071 Fatty acid degradation 7/423 45/7206 0.0149343316791 ko04975 Fat digestion and absorption 6/423 35/7206 0.0150065048319 ko00500 Starch and sucrose metabolism 6/423 35/7206 0.0150065048319 ko00982 Drug metabolism - cytochrome P450 6/423 37/7206 0.0194804590073 ko05204 Chemical carcinogenesis 7/423 48/7206 0.0208546284385 ko00260 Glycine, serine and threonine metabolism 7/423 48/7206 0.0208546284385 ko00592 alpha-Linolenic acid metabolism 4/423 19/7206 0.0224470694086 ko04270 Vascular smooth muscle contraction 16/423 154/7206 0.022985661922 ko00130 Ubiquinone and other terpenoid-quinone biosynthesis 3/423 11/7206 0.0232714892453 ko05203 Viral carcinogenesis 8/423 277/7206 0.0265613541839 ko00232 Caffeine metabolism 2/423 5/7206 0.0305359993058 ko00400 Phenylalanine, tyrosine and tryptophan biosynthesis 2/423 5/7206 0.0305359993058 ko00590 Arachidonic acid metabolism 7/423 52/7206 0.0310474431607 ko04914 Progesterone-mediated oocyte maturation 1/423 104/7206 0.0316926934967 ko05322 Systemic lupus erythematosus 3/423 151/7206 0.0350189392787 ko05012 Parkinson's disease 3/423 155/7206 0.0357654393523 ko04380 Osteoclast differentiation 14/423 134/7206 0.0377786970338 ko05323 Rheumatoid arthritis 10/423 89/7206 0.039387612136 ko05321 Inflammatory bowel disease (IBD) 7/423 56/7206 0.0441417999195 ko05144 Malaria 6/423 45/7206 0.0461903087124 ko00860 Porphyrin and chlorophyll metabolism 5/423 34/7206 0.046427734942 ko05224 Breast cancer 4/423 174/7206 0.0475595363897 ko04512 ECM-receptor interaction 9/423 79/7206 0.0490954218536