ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	123/747	423/7206	9.20795392441e-29
ko04724	Glutamatergic synapse	65/747	152/7206	1.0523767154e-25
ko05033	Nicotine addiction	37/747	56/7206	1.03644139318e-23
ko04727	GABAergic synapse	47/747	110/7206	7.71762622938e-19
ko05032	Morphine addiction	45/747	110/7206	3.37842846575e-17
ko04728	Dopaminergic synapse	60/747	185/7206	9.49674424092e-17
ko04713	Circadian entrainment	48/747	136/7206	3.09866150682e-15
ko04723	Retrograde endocannabinoid signaling	54/747	175/7206	3.73147312396e-14
ko04024	cAMP signaling pathway	70/747	279/7206	6.07830986469e-13
ko04725	Cholinergic synapse	48/747	160/7206	3.2899282568e-12
ko04721	Synaptic vesicle cycle	30/747	80/7206	9.50520569604e-11
ko04360	Axon guidance	57/747	233/7206	4.26134725621e-10
ko04911	Insulin secretion	35/747	117/7206	3.2971738601e-09
ko05030	Cocaine addiction	26/747	73/7206	6.20228125798e-09
ko04261	Adrenergic signaling in cardiomyocytes	46/747	205/7206	2.8883324214e-07
ko04742	Taste transduction	21/747	61/7206	3.51089856408e-07
ko04010	MAPK signaling pathway	63/747	321/7206	4.4429596813e-07
ko04514	Cell adhesion molecules (CAMs)	32/747	130/7206	2.69322382566e-06
ko03040	Spliceosome	1/747	145/7206	3.12415895637e-06
ko05031	Amphetamine addiction	25/747	91/7206	3.37469403742e-06
ko04921	Oxytocin signaling pathway	44/747	209/7206	4.36833868055e-06
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	22/747	79/7206	1.02399445166e-05
ko04726	Serotonergic synapse	32/747	137/7206	1.15690392483e-05
ko05203	Viral carcinogenesis	9/747	277/7206	1.183929694e-05
ko03013	RNA transport	3/747	166/7206	2.65507434225e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	20/747	74/7206	4.14041215173e-05
ko04020	Calcium signaling pathway	49/747	265/7206	4.97165158277e-05
ko04730	Long-term depression	20/747	78/7206	9.32382859154e-05
ko04970	Salivary secretion	23/747	95/7206	0.000103554278613
ko00240	Pyrimidine metabolism	1/747	110/7206	0.000115347986721
ko04720	Long-term potentiation	23/747	99/7206	0.000165696183722
ko04621	NOD-like receptor signaling pathway	4/747	157/7206	0.000293755825035
ko04120	Ubiquitin mediated proteolysis	3/747	138/7206	0.000347925070416
ko04972	Pancreatic secretion	24/747	111/7206	0.000409964818104
ko05414	Dilated cardiomyopathy	24/747	112/7206	0.000455106503891
ko05164	Influenza A	5/747	167/7206	0.000469991685578
ko05168	Herpes simplex infection	6/747	182/7206	0.000506147777268
ko04141	Protein processing in endoplasmic reticulum	6/747	184/7206	0.000511804073014
ko05322	Systemic lupus erythematosus	4/747	151/7206	0.000605483048449
ko04072	Phospholipase D signaling pathway	36/747	197/7206	0.000772862858755
ko04014	Ras signaling pathway	47/747	279/7206	0.000853166790712
ko04060	Cytokine-cytokine receptor interaction	7/747	191/7206	0.00101367958404
ko04260	Cardiac muscle contraction	21/747	98/7206	0.00114728550239
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/747	14/7206	0.00175766172749
ko03018	RNA degradation	1/747	84/7206	0.00181757035049
ko05169	Epstein-Barr virus infection	9/747	206/7206	0.00239762389042
ko04217	Necroptosis	7/747	178/7206	0.00254790663392
ko03008	Ribosome biogenesis in eukaryotes	1/747	79/7206	0.00267979099246
ko00515	Mannose type O-glycan biosynthesis	8/747	25/7206	0.0027877590908
ko01200	Carbon metabolism	4/747	128/7206	0.00324733290372
ko04015	Rap1 signaling pathway	44/747	278/7206	0.00354910000873
ko04064	NF-kappa B signaling pathway	2/747	96/7206	0.00359452655398
ko00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	8/747	26/7206	0.00366747693431
ko04932	Non-alcoholic fatty liver disease (NAFLD)	8/747	182/7206	0.00447742045029
ko04540	Gap junction	24/747	128/7206	0.00476512894473
ko05205	Proteoglycans in cancer	15/747	271/7206	0.00588411141397
ko04140	Autophagy - animal	7/747	164/7206	0.00624104821036
ko05162	Measles	4/747	120/7206	0.00629906904213
ko04022	cGMP-PKG signaling pathway	35/747	216/7206	0.00637284521341
ko04146	Peroxisome	2/747	89/7206	0.00755273178612
ko05410	Hypertrophic cardiomyopathy (HCM)	19/747	100/7206	0.00767559175223
ko04961	Endocrine and other factor-regulated calcium reabsorption	13/747	59/7206	0.00791599463312
ko04630	Jak-STAT signaling pathway	5/747	132/7206	0.00886941048285
ko04150	mTOR signaling pathway	9/747	184/7206	0.00990197198316
ko04640	Hematopoietic cell lineage	1/747	64/7206	0.0125256418352
ko04915	Estrogen signaling pathway	23/747	131/7206	0.0127801542684
ko04925	Aldosterone synthesis and secretion	19/747	105/7206	0.014429428418
ko04142	Lysosome	7/747	151/7206	0.0149604248784
ko04138	Autophagy - yeast	2/747	81/7206	0.0154252552733
ko04962	Vasopressin-regulated water reabsorption	12/747	58/7206	0.0159626242545
ko04218	Cellular senescence	9/747	177/7206	0.0170934641947
ko01212	Fatty acid metabolism	1/747	60/7206	0.0183473188794
ko05140	Leishmaniasis	2/747	75/7206	0.0214646284466
ko01524	Platinum drug resistance	2/747	76/7206	0.0216108553609
ko04612	Antigen processing and presentation	2/747	77/7206	0.0219576058477
ko05222	Small cell lung cancer	3/747	89/7206	0.0227276835758
ko04930	Type II diabetes mellitus	11/747	54/7206	0.0233626433381
ko04976	Bile secretion	15/747	80/7206	0.024216363956
ko04740	Olfactory transduction	15/747	80/7206	0.024216363956
ko05321	Inflammatory bowel disease (IBD)	1/747	56/7206	0.0268250680171
ko04744	Phototransduction	8/747	36/7206	0.0281494513881
ko04214	Apoptosis - fly	2/747	72/7206	0.0306854100773
ko00010	Glycolysis / Gluconeogenesis	2/747	74/7206	0.031911030816
ko04350	TGF-beta signaling pathway	4/747	103/7206	0.0321674058491
ko04391	Hippo signaling pathway - fly	16/747	90/7206	0.034078114975
ko05145	Toxoplasmosis	6/747	126/7206	0.0377160702644
ko00190	Oxidative phosphorylation	6/747	127/7206	0.0380960190803
ko00590	Arachidonic acid metabolism	1/747	52/7206	0.0391391284963
ko05215	Prostate cancer	5/747	111/7206	0.0402787106513
ko00520	Amino sugar and nucleotide sugar metabolism	1/747	55/7206	0.0411551592445
ko05161	Hepatitis B	10/747	173/7206	0.0432085981854
ko04137	Mitophagy - animal	3/747	82/7206	0.0437627521044
ko05146	Amoebiasis	4/747	99/7206	0.0438152636834
ko03320	PPAR signaling pathway	2/747	69/7206	0.0440831418942