ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	140/832	423/7206	2.26317727776e-34
ko05033	Nicotine addiction	46/832	56/7206	2.76424617768e-34
ko04724	Glutamatergic synapse	76/832	152/7206	1.92011805766e-32
ko05032	Morphine addiction	62/832	110/7206	1.72991460128e-30
ko04727	GABAergic synapse	59/832	110/7206	1.74915397432e-27
ko04723	Retrograde endocannabinoid signaling	70/832	175/7206	1.13047305204e-22
ko04713	Circadian entrainment	60/832	136/7206	3.55340281272e-22
ko04728	Dopaminergic synapse	71/832	185/7206	9.73506193983e-22
ko04024	cAMP signaling pathway	85/832	279/7206	2.88569582571e-18
ko04721	Synaptic vesicle cycle	40/832	80/7206	1.50501892045e-17
ko04725	Cholinergic synapse	59/832	160/7206	2.95578461627e-17
ko04911	Insulin secretion	45/832	117/7206	3.24088089231e-14
ko04742	Taste transduction	30/832	61/7206	3.12715930746e-13
ko04261	Adrenergic signaling in cardiomyocytes	59/832	205/7206	8.1527787751e-12
ko04921	Oxytocin signaling pathway	59/832	209/7206	2.45869114856e-11
ko04020	Calcium signaling pathway	67/832	265/7206	2.12679790005e-10
ko04726	Serotonergic synapse	43/832	137/7206	3.00927583415e-10
ko05030	Cocaine addiction	28/832	73/7206	2.65705371808e-09
ko04010	MAPK signaling pathway	74/832	321/7206	2.99995772682e-09
ko04720	Long-term potentiation	33/832	99/7206	6.71959588616e-09
ko05031	Amphetamine addiction	31/832	91/7206	1.07472975334e-08
ko05014	Amyotrophic lateral sclerosis (ALS)	26/832	74/7206	8.12907642391e-08
ko04744	Phototransduction	17/832	36/7206	1.00073258248e-07
ko04970	Salivary secretion	29/832	95/7206	4.72574375995e-07
ko03040	Spliceosome	1/832	145/7206	5.43274954979e-07
ko05203	Viral carcinogenesis	10/832	277/7206	3.05357310069e-06
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	24/832	79/7206	5.03976977494e-06
ko04360	Axon guidance	51/832	233/7206	5.12771412775e-06
ko04972	Pancreatic secretion	30/832	111/7206	6.17268392731e-06
ko04072	Phospholipase D signaling pathway	44/832	197/7206	1.23370937802e-05
ko04925	Aldosterone synthesis and secretion	28/832	105/7206	1.60757727324e-05
ko04514	Cell adhesion molecules (CAMs)	32/832	130/7206	2.24441315755e-05
ko04060	Cytokine-cytokine receptor interaction	6/832	191/7206	4.50008668533e-05
ko04730	Long-term depression	22/832	78/7206	4.50219362243e-05
ko05414	Dilated cardiomyopathy	28/832	112/7206	6.49644818826e-05
ko04961	Endocrine and other factor-regulated calcium reabsorption	18/832	59/7206	7.14740394814e-05
ko04022	cGMP-PKG signaling pathway	45/832	216/7206	7.87731939575e-05
ko05168	Herpes simplex infection	6/832	182/7206	8.80259397143e-05
ko04260	Cardiac muscle contraction	25/832	98/7206	9.29254981289e-05
ko03013	RNA transport	5/832	166/7206	0.000110735065616
ko04915	Estrogen signaling pathway	30/832	131/7206	0.000246520138253
ko04971	Gastric acid secretion	24/832	98/7206	0.000314062026911
ko04014	Ras signaling pathway	52/832	279/7206	0.000373973650328
ko05205	Proteoglycans in cancer	14/832	271/7206	0.000432277887399
ko05322	Systemic lupus erythematosus	5/832	151/7206	0.000438196994127
ko04740	Olfactory transduction	20/832	80/7206	0.000628607905119
ko04141	Protein processing in endoplasmic reticulum	8/832	184/7206	0.000948650743098
ko03008	Ribosome biogenesis in eukaryotes	1/832	79/7206	0.00115196496589
ko05164	Influenza A	7/832	167/7206	0.0012921241839
ko00240	Pyrimidine metabolism	3/832	110/7206	0.00137238914438
ko04540	Gap junction	27/832	128/7206	0.00181353954271
ko05410	Hypertrophic cardiomyopathy (HCM)	22/832	100/7206	0.00239373613663
ko04110	Cell cycle	6/832	145/7206	0.00239674595308
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/832	14/7206	0.00307987849308
ko04120	Ubiquitin mediated proteolysis	6/832	138/7206	0.00449354426861
ko03018	RNA degradation	2/832	84/7206	0.00507226774312
ko04640	Hematopoietic cell lineage	1/832	64/7206	0.00553118666476
ko04924	Renin secretion	19/832	86/7206	0.00554809119098
ko04371	Apelin signaling pathway	33/832	177/7206	0.00569217499197
ko04070	Phosphatidylinositol signaling system	23/832	112/7206	0.00646416320522
ko04932	Non-alcoholic fatty liver disease (NAFLD)	10/832	182/7206	0.00671813062385
ko04621	NOD-like receptor signaling pathway	8/832	157/7206	0.00765486489146
ko00330	Arginine and proline metabolism	1/832	61/7206	0.00814884730871
ko04930	Type II diabetes mellitus	13/832	54/7206	0.0084694252731
ko05140	Leishmaniasis	2/832	75/7206	0.0101215540678
ko04612	Antigen processing and presentation	2/832	77/7206	0.010538793689
ko04350	TGF-beta signaling pathway	4/832	103/7206	0.0118507152464
ko04015	Rap1 signaling pathway	46/832	278/7206	0.0123897546272
ko05034	Alcoholism	40/832	238/7206	0.0130370942584
ko05169	Epstein-Barr virus infection	13/832	206/7206	0.0146117410078
ko04666	Fc gamma R-mediated phagocytosis	23/832	122/7206	0.0148827583899
ko00280	Valine, leucine and isoleucine degradation	1/832	54/7206	0.0176564605423
ko00480	Glutathione metabolism	1/832	55/7206	0.0178451549959
ko04923	Regulation of lipolysis in adipocytes	16/832	77/7206	0.0180084451344
ko00515	Mannose type O-glycan biosynthesis	7/832	25/7206	0.0198050608611
ko04064	NF-kappa B signaling pathway	4/832	96/7206	0.0226725819181
ko04217	Necroptosis	11/832	178/7206	0.0232227588981
ko04966	Collecting duct acid secretion	7/832	26/7206	0.0244804505559
ko04071	Sphingolipid signaling pathway	28/832	162/7206	0.0250803105502
ko01200	Carbon metabolism	7/832	128/7206	0.0254563601963
ko05231	Choline metabolism in cancer	24/832	134/7206	0.0278499950758
ko04670	Leukocyte transendothelial migration	9/832	151/7206	0.0280708303824
ko04976	Bile secretion	16/832	80/7206	0.032161809836
ko04745	Phototransduction - fly	9/832	38/7206	0.0353040543252
ko05133	Pertussis	4/832	87/7206	0.0413904883695
ko01212	Fatty acid metabolism	2/832	60/7206	0.0418523003022
ko04146	Peroxisome	4/832	89/7206	0.042690924809
ko04140	Autophagy - animal	11/832	164/7206	0.0480110001063