ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 27/327 191/7206 1.10502090955e-07 ko00120 Primary bile acid biosynthesis 6/327 20/7206 0.000188201554117 ko04610 Complement and coagulation cascades 12/327 79/7206 0.000205454574899 ko04621 NOD-like receptor signaling pathway 18/327 157/7206 0.000250198110959 ko00643 Styrene degradation 3/327 4/7206 0.000358016120986 ko04064 NF-kappa B signaling pathway 13/327 96/7206 0.000363910202285 ko04710 Circadian rhythm 8/327 43/7206 0.000594416938558 ko05150 Staphylococcus aureus infection 7/327 36/7206 0.000993403290178 ko04668 TNF signaling pathway 14/327 120/7206 0.00101351129226 ko04380 Osteoclast differentiation 15/327 134/7206 0.00104210774517 ko04672 Intestinal immune network for IgA production 7/327 37/7206 0.00117836245132 ko04650 Natural killer cell mediated cytotoxicity 12/327 97/7206 0.00137556335275 ko04068 FoxO signaling pathway 17/327 167/7206 0.001833150973 ko05164 Influenza A 17/327 167/7206 0.001833150973 ko05321 Inflammatory bowel disease (IBD) 8/327 56/7206 0.00348888202324 ko05160 Hepatitis C 15/327 153/7206 0.00464202822512 ko04723 Retrograde endocannabinoid signaling 1/327 175/7206 0.00493622368337 ko04662 B cell receptor signaling pathway 10/327 88/7206 0.00625811416002 ko05323 Rheumatoid arthritis 10/327 89/7206 0.00677508172049 ko04217 Necroptosis 16/327 178/7206 0.00901333783505 ko00592 alpha-Linolenic acid metabolism 4/327 19/7206 0.00939008817596 ko00140 Steroid hormone biosynthesis 6/327 41/7206 0.00978673275586 ko05230 Central carbon metabolism in cancer 9/327 81/7206 0.010717837085 ko00051 Fructose and mannose metabolism 6/327 42/7206 0.0109941722591 ko04611 Platelet activation 15/327 163/7206 0.0111973885595 ko05152 Tuberculosis 16/327 187/7206 0.0122125647753 ko03320 PPAR signaling pathway 8/327 69/7206 0.0123555691885 ko05145 Toxoplasmosis 12/327 126/7206 0.0143798893731 ko05161 Hepatitis B 15/327 173/7206 0.0145707487592 ko03040 Spliceosome 1/327 145/7206 0.0148718459682 ko04110 Cell cycle 1/327 145/7206 0.0148718459682 ko05144 Malaria 6/327 45/7206 0.0152433637208 ko00350 Tyrosine metabolism 5/327 33/7206 0.0155560740808 ko04922 Glucagon signaling pathway 12/327 128/7206 0.0155850915721 ko04657 IL-17 signaling pathway 9/327 87/7206 0.0166462728409 ko05133 Pertussis 9/327 87/7206 0.0166462728409 ko05167 Kaposi's sarcoma-associated herpesvirus infection 16/327 191/7206 0.0195811716292 ko05034 Alcoholism 4/327 238/7206 0.0259056184583 ko04022 cGMP-PKG signaling pathway 17/327 216/7206 0.0285003874327 ko04931 Insulin resistance 12/327 137/7206 0.0337977977807 ko05215 Prostate cancer 10/327 111/7206 0.0342852816246 ko04658 Th1 and Th2 cell differentiation 9/327 96/7206 0.0408290489712 ko05340 Primary immunodeficiency 4/327 30/7206 0.0449917733948 ko05134 Legionellosis 7/327 74/7206 0.0497480801543