ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	177/1072	423/7206	3.45511207266e-44
ko04724	Glutamatergic synapse	84/1072	152/7206	1.20466467876e-31
ko05033	Nicotine addiction	47/1072	56/7206	1.04059520596e-30
ko04721	Synaptic vesicle cycle	54/1072	80/7206	9.90938089133e-27
ko04727	GABAergic synapse	60/1072	110/7206	1.81509170828e-22
ko04713	Circadian entrainment	68/1072	136/7206	1.89101975511e-22
ko05032	Morphine addiction	59/1072	110/7206	1.29018423661e-21
ko04728	Dopaminergic synapse	79/1072	185/7206	1.91300574507e-20
ko04725	Cholinergic synapse	72/1072	160/7206	2.62492583097e-20
ko04723	Retrograde endocannabinoid signaling	71/1072	175/7206	5.16830195297e-17
ko04742	Taste transduction	37/1072	61/7206	2.21105596622e-16
ko04024	cAMP signaling pathway	94/1072	279/7206	1.04905255656e-15
ko04911	Insulin secretion	52/1072	117/7206	1.03681184023e-14
ko04726	Serotonergic synapse	57/1072	137/7206	1.85881477326e-14
ko04921	Oxytocin signaling pathway	72/1072	209/7206	7.03230227225e-13
ko05031	Amphetamine addiction	42/1072	91/7206	8.30993798321e-13
ko04720	Long-term potentiation	43/1072	99/7206	5.68788319589e-12
ko04020	Calcium signaling pathway	82/1072	265/7206	1.29016183058e-11
ko04744	Phototransduction	23/1072	36/7206	2.47171530907e-11
ko04261	Adrenergic signaling in cardiomyocytes	66/1072	205/7206	2.07184039732e-10
ko03040	Spliceosome	1/1072	145/7206	2.2152171693e-09
ko04740	Olfactory transduction	33/1072	80/7206	8.34505697618e-09
ko04966	Collecting duct acid secretion	16/1072	26/7206	6.29442463913e-08
ko05168	Herpes simplex infection	5/1072	182/7206	7.07750498084e-08
ko04970	Salivary secretion	35/1072	95/7206	9.19612218573e-08
ko04060	Cytokine-cytokine receptor interaction	6/1072	191/7206	1.40103936973e-07
ko05030	Cocaine addiction	29/1072	73/7206	1.7896767467e-07
ko05203	Viral carcinogenesis	14/1072	277/7206	2.57791676122e-07
ko04971	Gastric acid secretion	35/1072	98/7206	3.48055680894e-07
ko05164	Influenza A	5/1072	167/7206	7.31767319738e-07
ko04120	Ubiquitin mediated proteolysis	3/1072	138/7206	7.71943053772e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	28/1072	74/7206	9.49040857596e-07
ko04360	Axon guidance	63/1072	233/7206	1.24849620519e-06
ko04925	Aldosterone synthesis and secretion	35/1072	105/7206	2.25357465532e-06
ko03013	RNA transport	6/1072	166/7206	3.97444007587e-06
ko04745	Phototransduction - fly	17/1072	38/7206	9.77105164246e-06
ko04924	Renin secretion	29/1072	86/7206	9.87540075201e-06
ko04260	Cardiac muscle contraction	31/1072	98/7206	2.16203708773e-05
ko04514	Cell adhesion molecules (CAMs)	38/1072	130/7206	2.71242840552e-05
ko04010	MAPK signaling pathway	75/1072	321/7206	3.76715226596e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	26/1072	79/7206	4.46266901119e-05
ko04621	NOD-like receptor signaling pathway	7/1072	157/7206	5.49317116599e-05
ko04141	Protein processing in endoplasmic reticulum	10/1072	184/7206	8.47616183782e-05
ko04540	Gap junction	36/1072	128/7206	8.51835804629e-05
ko04730	Long-term depression	25/1072	78/7206	0.000143683272622
ko05169	Epstein-Barr virus infection	13/1072	206/7206	0.00020495179637
ko05110	Vibrio cholerae infection	21/1072	63/7206	0.000221176772781
ko05162	Measles	5/1072	120/7206	0.000247264420992
ko04961	Endocrine and other factor-regulated calcium reabsorption	20/1072	59/7206	0.000272667821346
ko04022	cGMP-PKG signaling pathway	52/1072	216/7206	0.000292860937145
ko05322	Systemic lupus erythematosus	8/1072	151/7206	0.000296106720142
ko00604	Glycosphingolipid biosynthesis - ganglio series	8/1072	14/7206	0.000303819631317
ko04972	Pancreatic secretion	31/1072	111/7206	0.000371523815955
ko05205	Proteoglycans in cancer	21/1072	271/7206	0.00045904656837
ko04014	Ras signaling pathway	63/1072	279/7206	0.000549920731189
ko04612	Antigen processing and presentation	2/1072	77/7206	0.000618734810465
ko03008	Ribosome biogenesis in eukaryotes	2/1072	79/7206	0.00063527403734
ko05140	Leishmaniasis	2/1072	75/7206	0.000907895081434
ko04750	Inflammatory mediator regulation of TRP channels	32/1072	122/7206	0.00113499285133
ko04976	Bile secretion	23/1072	80/7206	0.00128676231106
ko04064	NF-kappa B signaling pathway	4/1072	96/7206	0.0012957358852
ko05161	Hepatitis B	12/1072	173/7206	0.00164345590322
ko04915	Estrogen signaling pathway	33/1072	131/7206	0.00175254433209
ko05414	Dilated cardiomyopathy	29/1072	112/7206	0.001928685697
ko04070	Phosphatidylinositol signaling system	29/1072	112/7206	0.001928685697
ko04110	Cell cycle	9/1072	145/7206	0.00196098513722
ko04964	Proximal tubule bicarbonate reclamation	11/1072	29/7206	0.00196617169309
ko04626	Plant-pathogen interaction	8/1072	18/7206	0.00254217271869
ko00240	Pyrimidine metabolism	6/1072	110/7206	0.00279919687092
ko00480	Glutathione metabolism	1/1072	55/7206	0.00337561213068
ko04146	Peroxisome	4/1072	89/7206	0.00382203953101
ko04640	Hematopoietic cell lineage	2/1072	64/7206	0.00418662994495
ko04932	Non-alcoholic fatty liver disease (NAFLD)	14/1072	182/7206	0.0042057391369
ko05166	HTLV-I infection	27/1072	292/7206	0.00427636013811
ko04072	Phospholipase D signaling pathway	44/1072	197/7206	0.00433015810861
ko00590	Arachidonic acid metabolism	1/1072	52/7206	0.0049724758125
ko03018	RNA degradation	4/1072	84/7206	0.00519091474356
ko04214	Apoptosis - fly	3/1072	72/7206	0.00695457604566
ko00310	Lysine degradation	3/1072	73/7206	0.00715621530876
ko04350	TGF-beta signaling pathway	6/1072	103/7206	0.00740198614683
ko04140	Autophagy - animal	13/1072	164/7206	0.0102230199319
ko00071	Fatty acid degradation	1/1072	45/7206	0.0105703377908
ko03420	Nucleotide excision repair	1/1072	46/7206	0.0108195783992
ko05120	Epithelial cell signaling in Helicobacter pylori infection	23/1072	92/7206	0.0111569279343
ko05321	Inflammatory bowel disease (IBD)	2/1072	56/7206	0.0129308078387
ko04657	IL-17 signaling pathway	5/1072	87/7206	0.014255996995
ko01524	Platinum drug resistance	4/1072	76/7206	0.0142704065107
ko05410	Hypertrophic cardiomyopathy (HCM)	24/1072	100/7206	0.015219142741
ko00983	Drug metabolism - other enzymes	1/1072	42/7206	0.0157069419981
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	6/1072	15/7206	0.0160629690758
ko03022	Basal transcription factors	1/1072	44/7206	0.0166718924495
ko04630	Jak-STAT signaling pathway	10/1072	132/7206	0.0181271235011
ko04668	TNF signaling pathway	9/1072	120/7206	0.019440183707
ko04622	RIG-I-like receptor signaling pathway	3/1072	62/7206	0.0197032173997
ko04620	Toll-like receptor signaling pathway	7/1072	100/7206	0.0230389978272
ko01200	Carbon metabolism	10/1072	128/7206	0.0232615513769
ko04916	Melanogenesis	31/1072	142/7206	0.0232720530556
ko00980	Metabolism of xenobiotics by cytochrome P450	1/1072	40/7206	0.0235745134681
ko00140	Steroid hormone biosynthesis	1/1072	41/7206	0.0244396693896
ko05034	Alcoholism	48/1072	238/7206	0.0256997716526
ko00330	Arginine and proline metabolism	3/1072	61/7206	0.0281687697994
ko04912	GnRH signaling pathway	27/1072	122/7206	0.0286630050792
ko05145	Toxoplasmosis	10/1072	126/7206	0.0306434478218
ko04371	Apelin signaling pathway	37/1072	177/7206	0.0316242787062
ko00982	Drug metabolism - cytochrome P450	1/1072	37/7206	0.0347796747577
ko00630	Glyoxylate and dicarboxylate metabolism	1/1072	38/7206	0.0358276333851
ko00270	Cysteine and methionine metabolism	2/1072	47/7206	0.0383355183924
ko00620	Pyruvate metabolism	2/1072	46/7206	0.0383583785784
ko03320	PPAR signaling pathway	4/1072	69/7206	0.0390169197085
ko05418	Fluid shear stress and atherosclerosis	16/1072	173/7206	0.0390724061531
ko04658	Th1 and Th2 cell differentiation	7/1072	96/7206	0.0415594706224
ko04115	p53 signaling pathway	5/1072	74/7206	0.0482770810101
ko04973	Carbohydrate digestion and absorption	11/1072	42/7206	0.0486891300345