ko pathway ratio_in_study ratio_in_pop p_value ko04512 ECM-receptor interaction 23/257 79/7206 1.55043682431e-15 ko05410 Hypertrophic cardiomyopathy (HCM) 25/257 100/7206 4.50616136145e-15 ko04974 Protein digestion and absorption 24/257 96/7206 1.63520951537e-14 ko04510 Focal adhesion 35/257 240/7206 5.24385221584e-13 ko04260 Cardiac muscle contraction 22/257 98/7206 2.27871332358e-12 ko05414 Dilated cardiomyopathy 23/257 112/7206 5.14638946838e-12 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 17/257 79/7206 1.58768762227e-09 ko01200 Carbon metabolism 19/257 128/7206 1.07573394593e-07 ko04261 Adrenergic signaling in cardiomyocytes 24/257 205/7206 2.32426158281e-07 ko05416 Viral myocarditis 11/257 55/7206 2.84886312735e-06 ko04921 Oxytocin signaling pathway 21/257 209/7206 1.56600034746e-05 ko00020 Citrate cycle (TCA cycle) 8/257 35/7206 2.39182575747e-05 ko00010 Glycolysis / Gluconeogenesis 11/257 74/7206 5.45739816159e-05 ko04020 Calcium signaling pathway 23/257 265/7206 6.49534016637e-05 ko04151 PI3K-Akt signaling pathway 29/257 390/7206 0.000184926346988 ko04022 cGMP-PKG signaling pathway 19/257 216/7206 0.000239494635839 ko04964 Proximal tubule bicarbonate reclamation 6/257 29/7206 0.000461694785966 ko00620 Pyruvate metabolism 7/257 46/7206 0.00109956624173 ko00680 Methane metabolism 6/257 34/7206 0.00112568021149 ko00710 Carbon fixation in photosynthetic organisms 5/257 27/7206 0.00235180974309 ko01230 Biosynthesis of amino acids 9/257 85/7206 0.00312816042606 ko00030 Pentose phosphate pathway 5/257 32/7206 0.00507424184514 ko04371 Apelin signaling pathway 14/257 177/7206 0.00569975056355 ko05010 Alzheimer's disease 15/257 202/7206 0.00616960263332 ko00500 Starch and sucrose metabolism 5/257 35/7206 0.00750053182733 ko04152 AMPK signaling pathway 13/257 161/7206 0.00752465370675 ko05146 Amoebiasis 9/257 99/7206 0.0085493860726 ko04810 Regulation of actin cytoskeleton 18/257 264/7206 0.00968114855381 ko04072 Phospholipase D signaling pathway 1/257 197/7206 0.0104331642166 ko04062 Chemokine signaling pathway 1/257 201/7206 0.0106002206441 ko04920 Adipocytokine signaling pathway 8/257 89/7206 0.0137154314743 ko05152 Tuberculosis 1/257 187/7206 0.0151383925929 ko05203 Viral carcinogenesis 3/257 277/7206 0.0191923671303 ko04922 Glucagon signaling pathway 10/257 128/7206 0.0249899470536 ko05012 Parkinson's disease 11/257 155/7206 0.025787656826 ko04140 Autophagy - animal 1/257 164/7206 0.0314554770263 ko03013 RNA transport 1/257 166/7206 0.0316744633677 ko00280 Valine, leucine and isoleucine degradation 5/257 54/7206 0.0424416158603 ko04142 Lysosome 1/257 151/7206 0.0451047245588 ko00250 Alanine, aspartate and glutamate metabolism 4/257 38/7206 0.0451503466271 ko04722 Neurotrophin signaling pathway 1/257 160/7206 0.0473321918021 ko04014 Ras signaling pathway 4/257 279/7206 0.0474177847535