ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	157/937	423/7206	4.78498421035e-39
ko04724	Glutamatergic synapse	74/937	152/7206	3.42100839475e-27
ko05033	Nicotine addiction	40/937	56/7206	9.04448708774e-24
ko04721	Synaptic vesicle cycle	48/937	80/7206	3.51552864245e-23
ko04728	Dopaminergic synapse	73/937	185/7206	4.70731957501e-20
ko05032	Morphine addiction	53/937	110/7206	1.69767878729e-19
ko04727	GABAergic synapse	52/937	110/7206	1.09617440562e-18
ko04713	Circadian entrainment	56/937	136/7206	1.28295314021e-16
ko04723	Retrograde endocannabinoid signaling	64/937	175/7206	8.86728394531e-16
ko04725	Cholinergic synapse	58/937	160/7206	3.2826647388e-14
ko04024	cAMP signaling pathway	83/937	279/7206	5.13720233888e-14
ko04726	Serotonergic synapse	47/937	137/7206	8.7607821072e-11
ko04921	Oxytocin signaling pathway	62/937	209/7206	1.0385519348e-10
ko05031	Amphetamine addiction	36/937	91/7206	1.54172053789e-10
ko04742	Taste transduction	28/937	61/7206	2.84644010755e-10
ko04966	Collecting duct acid secretion	17/937	26/7206	7.50795962804e-10
ko04261	Adrenergic signaling in cardiomyocytes	59/937	205/7206	1.19494992428e-09
ko04911	Insulin secretion	40/937	117/7206	2.54398012903e-09
ko04720	Long-term potentiation	35/937	99/7206	9.42318204584e-09
ko04744	Phototransduction	19/937	36/7206	1.19845286697e-08
ko04020	Calcium signaling pathway	67/937	265/7206	3.73781892581e-08
ko03040	Spliceosome	1/937	145/7206	5.76771441574e-08
ko04970	Salivary secretion	32/937	95/7206	1.49902749456e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	26/937	74/7206	8.7592409326e-07
ko04060	Cytokine-cytokine receptor interaction	5/937	191/7206	9.32593424141e-07
ko05203	Viral carcinogenesis	12/937	277/7206	1.55515316902e-06
ko04120	Ubiquitin mediated proteolysis	2/937	138/7206	2.1379835861e-06
ko05030	Cocaine addiction	25/937	73/7206	2.43899650094e-06
ko04360	Axon guidance	56/937	233/7206	3.67911607986e-06
ko03013	RNA transport	5/937	166/7206	1.15355633463e-05
ko05164	Influenza A	5/937	167/7206	1.16117598548e-05
ko05322	Systemic lupus erythematosus	4/937	151/7206	1.32838701911e-05
ko05110	Vibrio cholerae infection	21/937	63/7206	2.48107325956e-05
ko04924	Renin secretion	26/937	86/7206	2.60641466704e-05
ko04010	MAPK signaling pathway	68/937	321/7206	2.80174121018e-05
ko05168	Herpes simplex infection	7/937	182/7206	4.48568554898e-05
ko04730	Long-term depression	24/937	78/7206	4.83154666947e-05
ko05162	Measles	3/937	120/7206	9.58707488392e-05
ko04514	Cell adhesion molecules (CAMs)	33/937	130/7206	0.000105680257366
ko05120	Epithelial cell signaling in Helicobacter pylori infection	26/937	92/7206	0.000110491773449
ko00604	Glycosphingolipid biosynthesis - ganglio series	8/937	14/7206	0.000115443595089
ko04022	cGMP-PKG signaling pathway	48/937	216/7206	0.000129204153465
ko04925	Aldosterone synthesis and secretion	28/937	105/7206	0.000176984295118
ko04540	Gap junction	32/937	128/7206	0.000262684457888
ko04610	Complement and coagulation cascades	1/937	79/7206	0.000316839816048
ko03008	Ribosome biogenesis in eukaryotes	1/937	79/7206	0.000316839816048
ko04141	Protein processing in endoplasmic reticulum	9/937	184/7206	0.000338957033199
ko04971	Gastric acid secretion	26/937	98/7206	0.000361369264596
ko04621	NOD-like receptor signaling pathway	7/937	157/7206	0.000452977725237
ko04612	Antigen processing and presentation	1/937	77/7206	0.000478571779591
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	22/937	79/7206	0.000526455592428
ko04740	Olfactory transduction	22/937	80/7206	0.000571276747522
ko04964	Proximal tubule bicarbonate reclamation	11/937	29/7206	0.000628000858
ko04745	Phototransduction - fly	13/937	38/7206	0.000656402339552
ko05166	HTLV-I infection	20/937	292/7206	0.000940458533952
ko04626	Plant-pathogen interaction	8/937	18/7206	0.00103971054344
ko04014	Ras signaling pathway	55/937	279/7206	0.00138421193399
ko04110	Cell cycle	7/937	145/7206	0.00163933763626
ko04260	Cardiac muscle contraction	24/937	98/7206	0.00205067370265
ko05169	Epstein-Barr virus infection	13/937	206/7206	0.00222240969226
ko04972	Pancreatic secretion	26/937	111/7206	0.00243979855344
ko04146	Peroxisome	3/937	89/7206	0.00375112591276
ko04750	Inflammatory mediator regulation of TRP channels	27/937	122/7206	0.00422139699437
ko04214	Apoptosis - fly	2/937	72/7206	0.00457976216987
ko04064	NF-kappa B signaling pathway	4/937	96/7206	0.00564765577284
ko05161	Hepatitis B	11/937	173/7206	0.00589036271842
ko05414	Dilated cardiomyopathy	25/937	112/7206	0.00642561768312
ko04070	Phosphatidylinositol signaling system	25/937	112/7206	0.00642561768312
ko05205	Proteoglycans in cancer	21/937	271/7206	0.00737244698475
ko00280	Valine, leucine and isoleucine degradation	1/937	54/7206	0.00767833610579
ko00480	Glutathione metabolism	1/937	55/7206	0.00773376728453
ko05321	Inflammatory bowel disease (IBD)	1/937	56/7206	0.00795693953248
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	6/937	15/7206	0.00838626121755
ko00590	Arachidonic acid metabolism	1/937	52/7206	0.0114815556782
ko04915	Estrogen signaling pathway	27/937	131/7206	0.0124569851465
ko05140	Leishmaniasis	3/937	75/7206	0.0149124724205
ko01524	Platinum drug resistance	3/937	76/7206	0.0150832279214
ko05323	Rheumatoid arthritis	20/937	89/7206	0.0159001434743
ko04371	Apelin signaling pathway	34/937	177/7206	0.0170885295109
ko04072	Phospholipase D signaling pathway	37/937	197/7206	0.0179513958003
ko04961	Endocrine and other factor-regulated calcium reabsorption	14/937	59/7206	0.0194729057928
ko00330	Arginine and proline metabolism	2/937	61/7206	0.0199941773399
ko03018	RNA degradation	4/937	84/7206	0.0211758697584
ko00310	Lysine degradation	3/937	73/7206	0.0212924826484
ko04217	Necroptosis	13/937	178/7206	0.0232171781256
ko00071	Fatty acid degradation	1/937	45/7206	0.0248015725839
ko00620	Pyruvate metabolism	1/937	46/7206	0.0252044073579
ko03420	Nucleotide excision repair	1/937	46/7206	0.0252044073579
ko00910	Nitrogen metabolism	6/937	19/7206	0.028833474432
ko05217	Basal cell carcinoma	3/937	68/7206	0.0293093575186
ko00190	Oxidative phosphorylation	25/937	127/7206	0.0320765981135
ko05215	Prostate cancer	7/937	111/7206	0.0323384894193
ko04210	Apoptosis	14/937	180/7206	0.032786792155
ko04630	Jak-STAT signaling pathway	9/937	132/7206	0.0354485101369
ko00140	Steroid hormone biosynthesis	1/937	41/7206	0.0365334393627
ko00983	Drug metabolism - other enzymes	1/937	42/7206	0.0365606832602
ko03022	Basal transcription factors	1/937	44/7206	0.0386082242038
ko05034	Alcoholism	42/937	238/7206	0.0388625871766
ko05016	Huntington's disease	18/937	215/7206	0.0393388282375
ko04976	Bile secretion	17/937	80/7206	0.042349533547
ko04071	Sphingolipid signaling pathway	30/937	162/7206	0.0436228266177
ko04145	Phagosome	30/937	162/7206	0.0436228266177
ko00240	Pyrimidine metabolism	7/937	110/7206	0.0437442994028
ko00512	Mucin type O-glycan biosynthesis	8/937	29/7206	0.0451787001792
ko01200	Carbon metabolism	9/937	128/7206	0.0456055076236
ko05410	Hypertrophic cardiomyopathy (HCM)	20/937	100/7206	0.0496382973595