ko pathway ratio_in_study ratio_in_pop p_value ko04610 Complement and coagulation cascades 35/362 79/7206 3.00727008984e-25 ko04974 Protein digestion and absorption 24/362 96/7206 2.95693355327e-11 ko04975 Fat digestion and absorption 14/362 35/7206 4.50326098772e-10 ko04978 Mineral absorption 13/362 40/7206 3.66379712995e-08 ko04976 Bile secretion 18/362 80/7206 5.52831448112e-08 ko04977 Vitamin digestion and absorption 9/362 22/7206 5.13038769264e-07 ko04614 Renin-angiotensin system 8/362 18/7206 1.05514874729e-06 ko00983 Drug metabolism - other enzymes 11/362 42/7206 4.62927638401e-06 ko05150 Staphylococcus aureus infection 10/362 36/7206 7.10839668995e-06 ko04950 Maturity onset diabetes of the young 9/362 29/7206 7.54492203164e-06 ko02010 ABC transporters 10/362 39/7206 1.55283603137e-05 ko03320 PPAR signaling pathway 13/362 69/7206 3.11650553067e-05 ko04973 Carbohydrate digestion and absorption 10/362 42/7206 3.13958800942e-05 ko00340 Histidine metabolism 7/362 25/7206 0.000166714038759 ko04360 Axon guidance 1/362 233/7206 0.000167558410503 ko00350 Tyrosine metabolism 8/362 33/7206 0.000172205656978 ko04744 Phototransduction 8/362 36/7206 0.00032881230079 ko04964 Proximal tubule bicarbonate reclamation 7/362 29/7206 0.000454791697623 ko05169 Epstein-Barr virus infection 1/362 206/7206 0.000503409695381 ko00380 Tryptophan metabolism 9/362 50/7206 0.000739881312652 ko00830 Retinol metabolism 8/362 42/7206 0.000985088408791 ko04972 Pancreatic secretion 14/362 111/7206 0.00125084728501 ko00500 Starch and sucrose metabolism 7/362 35/7206 0.00151050502157 ko04010 MAPK signaling pathway 5/362 321/7206 0.00153973244373 ko04150 mTOR signaling pathway 1/362 184/7206 0.00161561008861 ko00120 Primary bile acid biosynthesis 5/362 20/7206 0.0025793113981 ko00100 Steroid biosynthesis 5/362 21/7206 0.00324799091672 ko04550 Signaling pathways regulating pluripotency of stem cells 1/362 165/7206 0.00332760667641 ko03013 RNA transport 1/362 166/7206 0.00335102329104 ko00140 Steroid hormone biosynthesis 7/362 41/7206 0.00389788346766 ko00591 Linoleic acid metabolism 5/362 22/7206 0.00403296466772 ko00480 Glutathione metabolism 8/362 55/7206 0.00575755978287 ko04144 Endocytosis 7/362 342/7206 0.00720021132602 ko04015 Rap1 signaling pathway 5/362 278/7206 0.00748418083346 ko00270 Cysteine and methionine metabolism 7/362 47/7206 0.00842746763088 ko00360 Phenylalanine metabolism 4/362 17/7206 0.00885146911212 ko04932 Non-alcoholic fatty liver disease (NAFLD) 2/362 182/7206 0.00885630305101 ko04141 Protein processing in endoplasmic reticulum 2/362 184/7206 0.00903240293283 ko05204 Chemical carcinogenesis 7/362 48/7206 0.00945288668194 ko00260 Glycine, serine and threonine metabolism 7/362 48/7206 0.00945288668194 ko00982 Drug metabolism - cytochrome P450 6/362 37/7206 0.00955340289887 ko05200 Pathways in cancer 13/362 492/7206 0.00993282465385 ko05016 Huntington's disease 3/362 215/7206 0.0100242582356 ko04110 Cell cycle 1/362 145/7206 0.0106367443901 ko00250 Alanine, aspartate and glutamate metabolism 6/362 38/7206 0.0108777621055 ko05133 Pertussis 10/362 87/7206 0.0114692279819 ko05161 Hepatitis B 2/362 173/7206 0.0124659918385 ko05224 Breast cancer 2/362 174/7206 0.0125492842827 ko04922 Glucagon signaling pathway 13/362 128/7206 0.0130575635249 ko04920 Adipocytokine signaling pathway 10/362 89/7206 0.0133474178625 ko05010 Alzheimer's disease 3/362 202/7206 0.0135202654116 ko00980 Metabolism of xenobiotics by cytochrome P450 6/362 40/7206 0.0139068747102 ko00643 Styrene degradation 2/362 4/7206 0.0141147060007 ko00965 Betalain biosynthesis 2/362 4/7206 0.0141147060007 ko00590 Arachidonic acid metabolism 7/362 52/7206 0.0144788258355 ko04630 Jak-STAT signaling pathway 1/362 132/7206 0.0147325181743 ko04120 Ubiquitin mediated proteolysis 1/362 138/7206 0.0156337569805 ko04152 AMPK signaling pathway 15/362 161/7206 0.0172751484708 ko04740 Olfactory transduction 9/362 80/7206 0.0183036736237 ko00053 Ascorbate and aldarate metabolism 4/362 22/7206 0.022328797622 ko00232 Caffeine metabolism 2/362 5/7206 0.0227474109074 ko00400 Phenylalanine, tyrosine and tryptophan biosynthesis 2/362 5/7206 0.0227474109074 ko00052 Galactose metabolism 5/362 33/7206 0.0231486552309 ko05203 Viral carcinogenesis 6/362 277/7206 0.0237807424981 ko04024 cAMP signaling pathway 6/362 279/7206 0.024007592927 ko04722 Neurotrophin signaling pathway 2/362 160/7206 0.0254753321233 ko00620 Pyruvate metabolism 6/362 46/7206 0.0264157520225 ko00410 beta-Alanine metabolism 5/362 35/7206 0.0291923197557 ko00770 Pantothenate and CoA biosynthesis 3/362 14/7206 0.0302749612382 ko04218 Cellular senescence 3/362 177/7206 0.0355273445386 ko01200 Carbon metabolism 12/362 128/7206 0.0369785050379 ko04913 Ovarian steroidogenesis 7/362 63/7206 0.0375613954181 ko00561 Glycerolipid metabolism 7/362 63/7206 0.0375613954181 ko00650 Butanoate metabolism 4/362 26/7206 0.0390187487167 ko04924 Renin secretion 9/362 86/7206 0.0395302796807 ko00630 Glyoxylate and dicarboxylate metabolism 5/362 38/7206 0.0399770174182 ko04012 ErbB signaling pathway 1/362 109/7206 0.0443651887614 ko04072 Phospholipase D signaling pathway 4/362 197/7206 0.0470064137208 ko04114 Oocyte meiosis 2/362 139/7206 0.0483221595628 ko05020 Prion diseases 5/362 40/7206 0.0483483783087 ko04014 Ras signaling pathway 7/362 279/7206 0.0495315210529