ko pathway ratio_in_study ratio_in_pop p_value ko04510 Focal adhesion 22/183 240/7206 1.44359383075e-07 ko05200 Pathways in cancer 33/183 492/7206 1.88812714294e-07 ko05205 Proteoglycans in cancer 23/183 271/7206 2.99626005776e-07 ko04810 Regulation of actin cytoskeleton 22/183 264/7206 7.59058754515e-07 ko05146 Amoebiasis 13/183 99/7206 1.09537004448e-06 ko05224 Breast cancer 17/183 174/7206 1.71407699611e-06 ko04390 Hippo signaling pathway 16/183 188/7206 2.06104691662e-05 ko04670 Leukocyte transendothelial migration 14/183 151/7206 2.66177497045e-05 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 10/183 79/7206 2.75219126959e-05 ko04916 Melanogenesis 13/183 142/7206 5.93827405472e-05 ko04550 Signaling pathways regulating pluripotency of stem cells 14/183 165/7206 7.12686217131e-05 ko04530 Tight junction 16/183 228/7206 0.000208737516563 ko04912 GnRH signaling pathway 11/183 122/7206 0.000253848177608 ko01522 Endocrine resistance 11/183 124/7206 0.000292749821683 ko05217 Basal cell carcinoma 8/183 68/7206 0.000298393555103 ko05206 MicroRNAs in cancer 13/183 177/7206 0.000538183786266 ko04933 AGE-RAGE signaling pathway in diabetic complications 11/183 135/7206 0.000608293450753 ko04512 ECM-receptor interaction 8/183 79/7206 0.000830652569877 ko04611 Platelet activation 12/183 163/7206 0.000861407749594 ko05100 Bacterial invasion of epithelial cells 9/183 99/7206 0.000874022051256 ko04668 TNF signaling pathway 10/183 120/7206 0.000902951567304 ko04514 Cell adhesion molecules (CAMs) 10/183 130/7206 0.00166601449108 ko05160 Hepatitis C 11/183 153/7206 0.00170761147985 ko00590 Arachidonic acid metabolism 6/183 52/7206 0.00190655074033 ko04151 PI3K-Akt signaling pathway 20/183 390/7206 0.00241501534583 ko04370 VEGF signaling pathway 7/183 77/7206 0.00326434945789 ko04666 Fc gamma R-mediated phagocytosis 9/183 122/7206 0.0037416095854 ko04015 Rap1 signaling pathway 15/183 278/7206 0.0052937294471 ko01521 EGFR tyrosine kinase inhibitor resistance 8/183 106/7206 0.00537822502907 ko05215 Prostate cancer 8/183 111/7206 0.00707602429306 ko05222 Small cell lung cancer 7/183 89/7206 0.00725639888508 ko04658 Th1 and Th2 cell differentiation 7/183 96/7206 0.0108308108508 ko05132 Salmonella infection 7/183 98/7206 0.0120531731955 ko04750 Inflammatory mediator regulation of TRP channels 8/183 122/7206 0.0122058757806 ko04730 Long-term depression 6/183 78/7206 0.0140051505779 ko04218 Cellular senescence 10/183 177/7206 0.0144672449783 ko05145 Toxoplasmosis 8/183 126/7206 0.0146220960409 ko04014 Ras signaling pathway 14/183 279/7206 0.0169836999403 ko04072 Phospholipase D signaling pathway 11/183 197/7206 0.0173151461355 ko05131 Shigellosis 6/183 82/7206 0.0175793708365 ko04915 Estrogen signaling pathway 8/183 131/7206 0.0181109059036 ko04144 Endocytosis 16/183 342/7206 0.0196596943528 ko05166 HTLV-I infection 14/183 292/7206 0.0204955986697 ko04012 ErbB signaling pathway 7/183 109/7206 0.0206097894938 ko05133 Pertussis 6/183 87/7206 0.0228706156533 ko00540 Lipopolysaccharide biosynthesis 1/183 1/7206 0.0253955037468 ko04310 Wnt signaling pathway 10/183 181/7206 0.0256414994632 ko05219 Bladder cancer 4/183 48/7206 0.0328820029725 ko04974 Protein digestion and absorption 6/183 96/7206 0.034905635959 ko04115 p53 signaling pathway 5/183 74/7206 0.039408806631 ko05410 Hypertrophic cardiomyopathy (HCM) 6/183 100/7206 0.0413591241252 ko05140 Leishmaniasis 5/183 75/7206 0.0413892688433 ko04320 Dorso-ventral axis formation 3/183 31/7206 0.0430295447213 ko04664 Fc epsilon RI signaling pathway 5/183 77/7206 0.0455284735834 ko04520 Adherens junction 6/183 103/7206 0.0466638078827 ko05142 Chagas disease (American trypanosomiasis) 7/183 130/7206 0.0471739717723 ko05214 Glioma 5/183 79/7206 0.0499066146489