ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	35/437	56/7206	2.77739923706e-29
ko04724	Glutamatergic synapse	49/437	152/7206	1.24283318317e-23
ko04080	Neuroactive ligand-receptor interaction	78/437	423/7206	5.62040662278e-20
ko04727	GABAergic synapse	35/437	110/7206	6.11638610495e-17
ko04723	Retrograde endocannabinoid signaling	43/437	175/7206	6.57584836233e-16
ko04728	Dopaminergic synapse	44/437	185/7206	1.08758266181e-15
ko05032	Morphine addiction	33/437	110/7206	3.46787562238e-15
ko04721	Synaptic vesicle cycle	25/437	80/7206	3.07135100376e-12
ko04713	Circadian entrainment	32/437	136/7206	1.41715461967e-11
ko04024	cAMP signaling pathway	47/437	279/7206	7.82709551018e-11
ko05030	Cocaine addiction	22/437	73/7206	1.4169470953e-10
ko05031	Amphetamine addiction	23/437	91/7206	2.56105796352e-09
ko04725	Cholinergic synapse	29/437	160/7206	7.65326819676e-08
ko04911	Insulin secretion	24/437	117/7206	9.34873023191e-08
ko04726	Serotonergic synapse	26/437	137/7206	1.41740061451e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	18/437	74/7206	2.67285157823e-07
ko04514	Cell adhesion molecules (CAMs)	24/437	130/7206	7.33785865037e-07
ko04010	MAPK signaling pathway	43/437	321/7206	8.55442075007e-07
ko04720	Long-term potentiation	19/437	99/7206	5.88118805919e-06
ko04742	Taste transduction	14/437	61/7206	1.19529656455e-05
ko04261	Adrenergic signaling in cardiomyocytes	28/437	205/7206	4.16515665937e-05
ko04921	Oxytocin signaling pathway	28/437	209/7206	8.17246548511e-05
ko04060	Cytokine-cytokine receptor interaction	1/437	191/7206	0.000153784797497
ko04020	Calcium signaling pathway	30/437	265/7206	0.000873077782369
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/437	14/7206	0.00101564852973
ko05203	Viral carcinogenesis	5/437	277/7206	0.00113134639795
ko03040	Spliceosome	1/437	145/7206	0.00224626818178
ko04730	Long-term depression	12/437	78/7206	0.00238109616332
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	12/437	79/7206	0.00265769273962
ko04140	Autophagy - animal	2/437	164/7206	0.00425710667731
ko03013	RNA transport	2/437	166/7206	0.00436441506889
ko05164	Influenza A	2/437	167/7206	0.00444162729938
ko01200	Carbon metabolism	1/437	128/7206	0.00467887617743
ko04072	Phospholipase D signaling pathway	22/437	197/7206	0.00561384263248
ko04621	NOD-like receptor signaling pathway	2/437	157/7206	0.00605075890831
ko04260	Cardiac muscle contraction	13/437	98/7206	0.00806131705859
ko04360	Axon guidance	24/437	233/7206	0.0110340454885
ko05205	Proteoglycans in cancer	7/437	271/7206	0.0128224973676
ko04915	Estrogen signaling pathway	15/437	131/7206	0.0150984443274
ko04611	Platelet activation	3/437	163/7206	0.0186188319529
ko04150	mTOR signaling pathway	4/437	184/7206	0.0186346752204
ko05410	Hypertrophic cardiomyopathy (HCM)	12/437	100/7206	0.0191733784457
ko04972	Pancreatic secretion	13/437	111/7206	0.023961371723
ko05414	Dilated cardiomyopathy	13/437	112/7206	0.0247221534169
ko04630	Jak-STAT signaling pathway	2/437	132/7206	0.0247760369025
ko05169	Epstein-Barr virus infection	5/437	206/7206	0.0249053524314
ko05034	Alcoholism	23/437	238/7206	0.0258531607764
ko05168	Herpes simplex infection	4/437	182/7206	0.0258851672807
ko04932	Non-alcoholic fatty liver disease (NAFLD)	4/437	182/7206	0.0258851672807
ko00512	Mucin type O-glycan biosynthesis	5/437	29/7206	0.0284574082034
ko05200	Pathways in cancer	19/437	492/7206	0.0312784533644
ko05162	Measles	2/437	120/7206	0.033864431481
ko04110	Cell cycle	3/437	145/7206	0.0349070577151
ko05322	Systemic lupus erythematosus	3/437	151/7206	0.0360143316592
ko00513	Various types of N-glycan biosynthesis	6/437	42/7206	0.0394443921755
ko04930	Type II diabetes mellitus	7/437	54/7206	0.0432116445898
ko04120	Ubiquitin mediated proteolysis	3/437	138/7206	0.0478481733129