ko pathway ratio_in_study ratio_in_pop p_value ko00340 Histidine metabolism 2/15 25/7206 0.00118030558282 ko05143 African trypanosomiasis 2/15 32/7206 0.00193508440677 ko00901 Indole alkaloid biosynthesis 1/15 1/7206 0.00208159866778 ko04744 Phototransduction 2/15 36/7206 0.00244608078419 ko04726 Serotonergic synapse 3/15 137/7206 0.00258713467017 ko04919 Thyroid hormone signaling pathway 3/15 143/7206 0.0029228092859 ko04710 Circadian rhythm 2/15 43/7206 0.00347668233629 ko04728 Dopaminergic synapse 3/15 185/7206 0.00603260248245 ko04961 Endocrine and other factor-regulated calcium reabsorption 2/15 59/7206 0.00646223033581 ko00965 Betalain biosynthesis 1/15 4/7206 0.00830215538999 ko04730 Long-term depression 2/15 78/7206 0.0110863156035 ko04918 Thyroid hormone synthesis 2/15 86/7206 0.0133645283412 ko05031 Amphetamine addiction 2/15 91/7206 0.0148839274828 ko04970 Salivary secretion 2/15 95/7206 0.0161511526611 ko04650 Natural killer cell mediated cytotoxicity 2/15 97/7206 0.0168017458886 ko04971 Gastric acid secretion 2/15 98/7206 0.0171312474664 ko04720 Long-term potentiation 2/15 99/7206 0.0174635371216 ko05146 Amoebiasis 2/15 99/7206 0.0174635371216 ko04925 Aldosterone synthesis and secretion 2/15 105/7206 0.0195151890872 ko00950 Isoquinoline alkaloid biosynthesis 1/15 10/7206 0.0206348465183 ko04972 Pancreatic secretion 2/15 111/7206 0.0216643679011 ko04070 Phosphatidylinositol signaling system 2/15 112/7206 0.0220318771489 ko04911 Insulin secretion 2/15 117/7206 0.0239086746291 ko04750 Inflammatory mediator regulation of TRP channels 2/15 122/7206 0.0258498927687 ko04540 Gap junction 2/15 128/7206 0.0282624949513 ko00770 Pantothenate and CoA biosynthesis 1/15 14/7206 0.0287769543192 ko05231 Choline metabolism in cancer 2/15 134/7206 0.0307636313209 ko04713 Circadian entrainment 2/15 136/7206 0.0316166265846 ko04916 Melanogenesis 2/15 142/7206 0.0342323040046 ko00360 Phenylalanine metabolism 1/15 17/7206 0.0348420266166 ko04670 Leukocyte transendothelial migration 2/15 151/7206 0.0383113716897 ko04724 Glutamatergic synapse 2/15 152/7206 0.0387758555816 ko00910 Nitrogen metabolism 1/15 19/7206 0.038865749215 ko04270 Vascular smooth muscle contraction 2/15 154/7206 0.039711456622 ko04725 Cholinergic synapse 2/15 160/7206 0.0425706190923 ko04071 Sphingolipid signaling pathway 2/15 162/7206 0.0435408665533