ko pathway ratio_in_study ratio_in_pop p_value ko04380 Osteoclast differentiation 25/391 134/7206 4.02205665068e-08 ko04060 Cytokine-cytokine receptor interaction 28/391 191/7206 1.19664807481e-06 ko05140 Leishmaniasis 14/391 75/7206 4.08467961522e-05 ko04650 Natural killer cell mediated cytotoxicity 16/391 97/7206 5.73220591275e-05 ko05321 Inflammatory bowel disease (IBD) 11/391 56/7206 0.000169796549295 ko05167 Kaposi's sarcoma-associated herpesvirus infection 23/391 191/7206 0.000269014623829 ko04610 Complement and coagulation cascades 13/391 79/7206 0.000289263484532 ko05164 Influenza A 21/391 167/7206 0.000333395663703 ko04137 Mitophagy - animal 13/391 82/7206 0.000421669646763 ko04659 Th17 cell differentiation 15/391 106/7206 0.000551264518488 ko04672 Intestinal immune network for IgA production 8/391 37/7206 0.00067216466465 ko05152 Tuberculosis 22/391 187/7206 0.000776827473743 ko00140 Steroid hormone biosynthesis 8/391 41/7206 0.00137524215574 ko00051 Fructose and mannose metabolism 8/391 42/7206 0.0016200407975 ko04658 Th1 and Th2 cell differentiation 13/391 96/7206 0.00191581046448 ko04621 NOD-like receptor signaling pathway 18/391 157/7206 0.00216640555663 ko04070 Phosphatidylinositol signaling system 14/391 112/7206 0.00280686793425 ko00592 alpha-Linolenic acid metabolism 5/391 19/7206 0.00283054043313 ko05162 Measles 15/391 120/7206 0.00317915085304 ko00120 Primary bile acid biosynthesis 5/391 20/7206 0.0036085510308 ko05145 Toxoplasmosis 15/391 126/7206 0.00408298501511 ko05230 Central carbon metabolism in cancer 11/391 81/7206 0.00409063062938 ko03040 Spliceosome 1/391 145/7206 0.00478061008225 ko05340 Primary immunodeficiency 6/391 30/7206 0.00479895500087 ko04630 Jak-STAT signaling pathway 15/391 132/7206 0.00565505222635 ko04666 Fc gamma R-mediated phagocytosis 14/391 122/7206 0.00715538012646 ko04662 B cell receptor signaling pathway 11/391 88/7206 0.00769791996327 ko04710 Circadian rhythm 7/391 43/7206 0.00776207920448 ko04660 T cell receptor signaling pathway 14/391 124/7206 0.00798010136631 ko04664 Fc epsilon RI signaling pathway 10/391 77/7206 0.00832088074563 ko03013 RNA transport 2/391 166/7206 0.00866889954556 ko05418 Fluid shear stress and atherosclerosis 18/391 173/7206 0.00934437265068 ko01040 Biosynthesis of unsaturated fatty acids 5/391 25/7206 0.00989209337717 ko05144 Malaria 7/391 45/7206 0.00996253326917 ko03010 Ribosome 1/391 129/7206 0.0100636793266 ko05160 Hepatitis C 16/391 153/7206 0.0103615758837 ko04217 Necroptosis 18/391 178/7206 0.0105559502647 ko05150 Staphylococcus aureus infection 6/391 36/7206 0.0119718438855 ko04218 Cellular senescence 17/391 177/7206 0.0183135928428 ko04933 AGE-RAGE signaling pathway in diabetic complications 14/391 135/7206 0.0188622330051 ko04611 Platelet activation 16/391 163/7206 0.0208662358048 ko00590 Arachidonic acid metabolism 7/391 52/7206 0.0212597076828 ko04960 Aldosterone-regulated sodium reabsorption 6/391 41/7206 0.0220329391626 ko04066 HIF-1 signaling pathway 13/391 123/7206 0.0236602183371 ko00565 Ether lipid metabolism 6/391 42/7206 0.0245705161867 ko04670 Leukocyte transendothelial migration 15/391 151/7206 0.0264359329081 ko05168 Herpes simplex infection 17/391 182/7206 0.0288908205888 ko04711 Circadian rhythm - fly 3/391 13/7206 0.0301881291971 ko00052 Galactose metabolism 5/391 33/7206 0.0310305728278 ko05231 Choline metabolism in cancer 13/391 134/7206 0.0341299023815 ko05330 Allograft rejection 4/391 24/7206 0.0383055604184 ko05161 Hepatitis B 16/391 173/7206 0.0386075159008 ko05132 Salmonella infection 10/391 98/7206 0.0431768768727 ko05166 HTLV-I infection 24/391 292/7206 0.0461592783344