ko pathway ratio_in_study ratio_in_pop p_value ko05143 African trypanosomiasis 2/16 32/7206 0.00220540496356 ko04015 Rap1 signaling pathway 4/16 278/7206 0.00273175828491 ko04745 Phototransduction - fly 2/16 38/7206 0.00310163289708 ko04961 Endocrine and other factor-regulated calcium reabsorption 2/16 59/7206 0.00734673536226 ko05010 Alzheimer's disease 3/16 202/7206 0.0092811350612 ko04730 Long-term depression 2/16 78/7206 0.012581881642 ko04924 Renin secretion 2/16 86/7206 0.0151563865584 ko04918 Thyroid hormone synthesis 2/16 86/7206 0.0151563865584 ko04970 Salivary secretion 2/16 95/7206 0.0183016567889 ko04971 Gastric acid secretion 2/16 98/7206 0.0194069665418 ko04720 Long-term potentiation 2/16 99/7206 0.0197816035387 ko05146 Amoebiasis 2/16 99/7206 0.0197816035387 ko04925 Aldosterone synthesis and secretion 2/16 105/7206 0.0220935713181 ko00130 Ubiquinone and other terpenoid-quinone biosynthesis 1/16 11/7206 0.0241713268882 ko04972 Pancreatic secretion 2/16 111/7206 0.0245133914084 ko04911 Insulin secretion 2/16 117/7206 0.0270381790608 ko04912 GnRH signaling pathway 2/16 122/7206 0.0292203051952 ko04750 Inflammatory mediator regulation of TRP channels 2/16 122/7206 0.0292203051952 ko00730 Thiamine metabolism 1/16 14/7206 0.0306678071412 ko04922 Glucagon signaling pathway 2/16 128/7206 0.0319302040506 ko04540 Gap junction 2/16 128/7206 0.0319302040506 ko05142 Chagas disease (American trypanosomiasis) 2/16 130/7206 0.032855206697 ko04915 Estrogen signaling pathway 2/16 131/7206 0.0333217205658 ko04713 Circadian entrainment 2/16 136/7206 0.0356939158125 ko04726 Serotonergic synapse 2/16 137/7206 0.0361761931919 ko02020 Two-component system 1/16 17/7206 0.0371237239536 ko04916 Melanogenesis 2/16 142/7206 0.0386260952657 ko04724 Glutamatergic synapse 2/16 152/7206 0.0437136302154 ko04270 Vascular smooth muscle contraction 2/16 154/7206 0.0447603612359 ko00790 Folate biosynthesis 1/16 21/7206 0.0456689229108 ko04725 Cholinergic synapse 2/16 160/7206 0.047957309749 ko04071 Sphingolipid signaling pathway 2/16 162/7206 0.0490415688757 ko04611 Platelet activation 2/16 163/7206 0.0495871360446