ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	179/1076	423/7206	2.64499748992e-45
ko04724	Glutamatergic synapse	80/1076	152/7206	4.20285468471e-28
ko05033	Nicotine addiction	44/1076	56/7206	1.93420869838e-26
ko04728	Dopaminergic synapse	83/1076	185/7206	4.76462572416e-23
ko05032	Morphine addiction	60/1076	110/7206	2.21210941478e-22
ko04727	GABAergic synapse	58/1076	110/7206	1.06713978089e-20
ko04721	Synaptic vesicle cycle	48/1076	80/7206	1.56660003388e-20
ko04713	Circadian entrainment	65/1076	136/7206	4.53889105353e-20
ko04725	Cholinergic synapse	71/1076	160/7206	1.60252930507e-19
ko04723	Retrograde endocannabinoid signaling	71/1076	175/7206	6.35356979391e-17
ko04024	cAMP signaling pathway	93/1076	279/7206	3.29932864717e-15
ko04742	Taste transduction	35/1076	61/7206	1.79893673407e-14
ko04911	Insulin secretion	50/1076	117/7206	2.59280897715e-13
ko04921	Oxytocin signaling pathway	73/1076	209/7206	2.91597587859e-13
ko04726	Serotonergic synapse	55/1076	137/7206	3.78060984509e-13
ko04020	Calcium signaling pathway	84/1076	265/7206	1.93344439266e-12
ko04261	Adrenergic signaling in cardiomyocytes	68/1076	205/7206	2.68423396088e-11
ko05031	Amphetamine addiction	38/1076	91/7206	4.48192420061e-10
ko04360	Axon guidance	71/1076	233/7206	8.91557718795e-10
ko03040	Spliceosome	1/1076	145/7206	2.18713792352e-09
ko04744	Phototransduction	21/1076	36/7206	2.22579881387e-09
ko04720	Long-term potentiation	38/1076	99/7206	7.71972979618e-09
ko05203	Viral carcinogenesis	12/1076	277/7206	1.39483672761e-08
ko04970	Salivary secretion	36/1076	95/7206	2.84154658038e-08
ko05168	Herpes simplex infection	6/1076	182/7206	4.29074048026e-07
ko04060	Cytokine-cytokine receptor interaction	7/1076	191/7206	5.1567304913e-07
ko03013	RNA transport	5/1076	166/7206	7.14384991587e-07
ko04010	MAPK signaling pathway	80/1076	321/7206	1.77685191896e-06
ko04740	Olfactory transduction	29/1076	80/7206	1.84977732293e-06
ko04971	Gastric acid secretion	33/1076	98/7206	2.59089208892e-06
ko05164	Influenza A	6/1076	167/7206	2.6706568918e-06
ko05322	Systemic lupus erythematosus	5/1076	151/7206	4.5532469496e-06
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	28/1076	79/7206	7.24574878037e-06
ko05030	Cocaine addiction	26/1076	73/7206	9.09931230675e-06
ko04022	cGMP-PKG signaling pathway	57/1076	216/7206	9.75612956985e-06
ko04924	Renin secretion	29/1076	86/7206	1.05189858176e-05
ko04925	Aldosterone synthesis and secretion	33/1076	105/7206	2.039844409e-05
ko04141	Protein processing in endoplasmic reticulum	9/1076	184/7206	2.17378011419e-05
ko04120	Ubiquitin mediated proteolysis	5/1076	138/7206	2.93079470796e-05
ko04621	NOD-like receptor signaling pathway	7/1076	157/7206	3.71605707544e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	25/1076	74/7206	4.39567995197e-05
ko04745	Phototransduction - fly	16/1076	38/7206	4.70345594036e-05
ko04514	Cell adhesion molecules (CAMs)	37/1076	130/7206	5.64168769307e-05
ko04260	Cardiac muscle contraction	30/1076	98/7206	7.62800274524e-05
ko03008	Ribosome biogenesis in eukaryotes	1/1076	79/7206	8.41472918459e-05
ko04014	Ras signaling pathway	66/1076	279/7206	0.00010129228839
ko04540	Gap junction	36/1076	128/7206	0.000130985093129
ko04966	Collecting duct acid secretion	12/1076	26/7206	0.000146089003077
ko04730	Long-term depression	25/1076	78/7206	0.000147548299659
ko05414	Dilated cardiomyopathy	32/1076	112/7206	0.00023257151697
ko00604	Glycosphingolipid biosynthesis - ganglio series	8/1076	14/7206	0.000311983937273
ko04612	Antigen processing and presentation	2/1076	77/7206	0.000614564586349
ko04961	Endocrine and other factor-regulated calcium reabsorption	19/1076	59/7206	0.000700137968456
ko05161	Hepatitis B	11/1076	173/7206	0.000727078801109
ko05140	Leishmaniasis	2/1076	75/7206	0.000907366083773
ko05169	Epstein-Barr virus infection	15/1076	206/7206	0.00099572289967
ko04064	NF-kappa B signaling pathway	4/1076	96/7206	0.00129714847092
ko05205	Proteoglycans in cancer	23/1076	271/7206	0.00167950924494
ko04972	Pancreatic secretion	29/1076	111/7206	0.00182236131968
ko04750	Inflammatory mediator regulation of TRP channels	31/1076	122/7206	0.00199383036268
ko04070	Phosphatidylinositol signaling system	29/1076	112/7206	0.00200081661552
ko04146	Peroxisome	4/1076	89/7206	0.00260503511984
ko00480	Glutathione metabolism	1/1076	55/7206	0.003409663786
ko05410	Hypertrophic cardiomyopathy (HCM)	26/1076	100/7206	0.00415420716214
ko04640	Hematopoietic cell lineage	2/1076	64/7206	0.00418887487517
ko04110	Cell cycle	10/1076	145/7206	0.00443115482139
ko00590	Arachidonic acid metabolism	1/1076	52/7206	0.0050120536401
ko00330	Arginine and proline metabolism	2/1076	61/7206	0.00608595799413
ko05110	Vibrio cholerae infection	18/1076	63/7206	0.00652728924806
ko04072	Phospholipase D signaling pathway	43/1076	197/7206	0.0081975754191
ko04932	Non-alcoholic fatty liver disease (NAFLD)	15/1076	182/7206	0.00824010606829
ko04668	TNF signaling pathway	8/1076	120/7206	0.00913618649594
ko05162	Measles	8/1076	120/7206	0.00913618649594
ko00240	Pyrimidine metabolism	7/1076	110/7206	0.00968984583258
ko04371	Apelin signaling pathway	39/1076	177/7206	0.0101013732405
ko00071	Fatty acid degradation	1/1076	45/7206	0.0105668146405
ko03022	Basal transcription factors	1/1076	44/7206	0.0105695612947
ko03420	Nucleotide excision repair	1/1076	46/7206	0.0108677860407
ko04626	Plant-pathogen interaction	7/1076	18/7206	0.0114324302113
ko05321	Inflammatory bowel disease (IBD)	2/1076	56/7206	0.0129627624671
ko04915	Estrogen signaling pathway	30/1076	131/7206	0.0131044713062
ko04630	Jak-STAT signaling pathway	10/1076	132/7206	0.0134866627714
ko01524	Platinum drug resistance	4/1076	76/7206	0.0142836959734
ko04916	Melanogenesis	32/1076	142/7206	0.016596680285
ko04976	Bile secretion	20/1076	80/7206	0.0168837567553
ko05418	Fluid shear stress and atherosclerosis	15/1076	173/7206	0.0172423253592
ko00280	Valine, leucine and isoleucine degradation	2/1076	54/7206	0.0192229057669
ko05131	Shigellosis	5/1076	82/7206	0.0192338984274
ko03018	RNA degradation	5/1076	84/7206	0.0195841715113
ko04622	RIG-I-like receptor signaling pathway	3/1076	62/7206	0.0196398989677
ko00561	Glycerolipid metabolism	3/1076	63/7206	0.0197381245742
ko04214	Apoptosis - fly	4/1076	72/7206	0.0197597465068
ko00310	Lysine degradation	4/1076	73/7206	0.019821697486
ko04620	Toll-like receptor signaling pathway	7/1076	100/7206	0.023040896872
ko05145	Toxoplasmosis	10/1076	126/7206	0.0230483792877
ko01200	Carbon metabolism	10/1076	128/7206	0.0233670733948
ko00980	Metabolism of xenobiotics by cytochrome P450	1/1076	40/7206	0.0236202748952
ko00140	Steroid hormone biosynthesis	1/1076	41/7206	0.0245808015427
ko00380	Tryptophan metabolism	2/1076	50/7206	0.0267798803198
ko04964	Proximal tubule bicarbonate reclamation	9/1076	29/7206	0.0306042933309
ko04658	Th1 and Th2 cell differentiation	7/1076	96/7206	0.0306214675242
ko04930	Type II diabetes mellitus	14/1076	54/7206	0.0328298268434
ko05133	Pertussis	6/1076	87/7206	0.0332668673333
ko00982	Drug metabolism - cytochrome P450	1/1076	37/7206	0.0348157346748
ko04140	Autophagy - animal	15/1076	164/7206	0.034865526485
ko04391	Hippo signaling pathway - fly	21/1076	90/7206	0.0355080274221
ko05166	HTLV-I infection	31/1076	292/7206	0.03578695397
ko04350	TGF-beta signaling pathway	8/1076	103/7206	0.0368070938721
ko00620	Pyruvate metabolism	2/1076	46/7206	0.038243385115
ko00270	Cysteine and methionine metabolism	2/1076	47/7206	0.0383451281185
ko04015	Rap1 signaling pathway	54/1076	278/7206	0.0389523544086
ko05219	Bladder cancer	2/1076	48/7206	0.0391717031724
ko05206	MicroRNAs in cancer	17/1076	177/7206	0.0425238718553
ko04217	Necroptosis	17/1076	178/7206	0.0425721955502
ko05215	Prostate cancer	9/1076	111/7206	0.0433104344447
ko04115	p53 signaling pathway	5/1076	74/7206	0.0482610294798