ko pathway ratio_in_study ratio_in_pop p_value ko04724 Glutamatergic synapse 29/381 152/7206 1.00936522506e-09 ko04020 Calcium signaling pathway 37/381 265/7206 3.99348059747e-08 ko04925 Aldosterone synthesis and secretion 21/381 105/7206 9.39768991578e-08 ko05032 Morphine addiction 20/381 110/7206 9.59945615399e-07 ko04070 Phosphatidylinositol signaling system 20/381 112/7206 1.29245733311e-06 ko04911 Insulin secretion 20/381 117/7206 2.63042996166e-06 ko04725 Cholinergic synapse 24/381 160/7206 2.98634878751e-06 ko04713 Circadian entrainment 21/381 136/7206 7.88521605065e-06 ko04727 GABAergic synapse 18/381 110/7206 1.5639429484e-05 ko04710 Circadian rhythm 10/381 43/7206 6.04768891179e-05 ko04080 Neuroactive ligand-receptor interaction 42/381 423/7206 6.84613770262e-05 ko04930 Type II diabetes mellitus 11/381 54/7206 9.54541517718e-05 ko04072 Phospholipase D signaling pathway 24/381 197/7206 0.000121642074123 ko05033 Nicotine addiction 11/381 56/7206 0.000134975798713 ko04720 Long-term potentiation 15/381 99/7206 0.000195357164648 ko04022 cGMP-PKG signaling pathway 25/381 216/7206 0.000258439943586 ko04921 Oxytocin signaling pathway 24/381 209/7206 0.00038507516118 ko04723 Retrograde endocannabinoid signaling 21/381 175/7206 0.000406406313509 ko04970 Salivary secretion 14/381 95/7206 0.000425684908715 ko04261 Adrenergic signaling in cardiomyocytes 23/381 205/7206 0.000638765663869 ko04010 MAPK signaling pathway 31/381 321/7206 0.00120497419132 ko04742 Taste transduction 10/381 61/7206 0.00121441962866 ko04728 Dopaminergic synapse 20/381 185/7206 0.00218922937892 ko03013 RNA transport 1/381 166/7206 0.00229814933014 ko00562 Inositol phosphate metabolism 12/381 89/7206 0.00236794038172 ko05031 Amphetamine addiction 12/381 91/7206 0.00286203652862 ko04721 Synaptic vesicle cycle 11/381 80/7206 0.00304110454496 ko04711 Circadian rhythm - fly 4/381 13/7206 0.00375591124065 ko04024 cAMP signaling pathway 26/381 279/7206 0.00400228557388 ko04514 Cell adhesion molecules (CAMs) 15/381 130/7206 0.00424453987141 ko00561 Glycerolipid metabolism 9/381 63/7206 0.00549924262316 ko00513 Various types of N-glycan biosynthesis 7/381 42/7206 0.00592110063621 ko03040 Spliceosome 1/381 145/7206 0.0072482299328 ko04730 Long-term depression 10/381 78/7206 0.00763777169139 ko04972 Pancreatic secretion 13/381 111/7206 0.0078200444184 ko04922 Glucagon signaling pathway 14/381 128/7206 0.00834341119466 ko04745 Phototransduction - fly 6/381 38/7206 0.0137710728398 ko00471 D-Glutamine and D-glutamate metabolism 2/381 4/7206 0.0155808269204 ko05414 Dilated cardiomyopathy 12/381 112/7206 0.0170196504554 ko04726 Serotonergic synapse 14/381 137/7206 0.0180032604315 ko04260 Cardiac muscle contraction 11/381 98/7206 0.0186524951079 ko00564 Glycerophospholipid metabolism 11/381 99/7206 0.019427693806 ko04923 Regulation of lipolysis in adipocytes 9/381 77/7206 0.0196454906468 ko04013 MAPK signaling pathway - fly 12/381 115/7206 0.0198435841058 ko04924 Renin secretion 10/381 86/7206 0.0239040109064 ko04918 Thyroid hormone synthesis 10/381 86/7206 0.0239040109064 ko05164 Influenza A 3/381 167/7206 0.0353555710804 ko04110 Cell cycle 2/381 145/7206 0.035877183191 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 9/381 79/7206 0.0362262588432 ko05203 Viral carcinogenesis 7/381 277/7206 0.0384603758961 ko04270 Vascular smooth muscle contraction 14/381 154/7206 0.0430399399662 ko00510 N-Glycan biosynthesis 6/381 50/7206 0.0468305510662 ko04145 Phagosome 3/381 162/7206 0.0487405694343