ko pathway ratio_in_study ratio_in_pop p_value ko04668 TNF signaling pathway 11/84 120/7206 1.14740826203e-07 ko05131 Shigellosis 9/84 82/7206 3.7723044656e-07 ko05100 Bacterial invasion of epithelial cells 9/84 99/7206 1.89785669376e-06 ko05132 Salmonella infection 8/84 98/7206 1.63471766978e-05 ko04932 Non-alcoholic fatty liver disease (NAFLD) 10/84 182/7206 4.51013734816e-05 ko04621 NOD-like receptor signaling pathway 9/84 157/7206 8.01592933442e-05 ko05134 Legionellosis 6/84 74/7206 0.000206130717352 ko05145 Toxoplasmosis 7/84 126/7206 0.000627428293533 ko05120 Epithelial cell signaling in Helicobacter pylori infection 6/84 92/7206 0.000671580373722 ko05164 Influenza A 8/84 167/7206 0.000686397004084 ko04217 Necroptosis 8/84 178/7206 0.00104207953003 ko05410 Hypertrophic cardiomyopathy (HCM) 6/84 100/7206 0.00104261799286 ko04623 Cytosolic DNA-sensing pathway 4/84 41/7206 0.00125310038397 ko04060 Cytokine-cytokine receptor interaction 8/84 191/7206 0.00163872533572 ko04510 Focal adhesion 9/84 240/7206 0.00181069717392 ko04512 ECM-receptor interaction 5/84 79/7206 0.00218955454082 ko05133 Pertussis 5/84 87/7206 0.00333868282288 ko04920 Adipocytokine signaling pathway 5/84 89/7206 0.00368321075385 ko04933 AGE-RAGE signaling pathway in diabetic complications 6/84 135/7206 0.00475725693465 ko04210 Apoptosis 7/84 180/7206 0.00484639734193 ko05168 Herpes simplex infection 7/84 182/7206 0.00514631521467 ko05146 Amoebiasis 5/84 99/7206 0.00579795000188 ko05160 Hepatitis C 6/84 153/7206 0.00865922217494 ko04722 Neurotrophin signaling pathway 6/84 160/7206 0.0106676417518 ko05130 Pathogenic Escherichia coli infection 4/84 77/7206 0.0122041062707 ko04068 FoxO signaling pathway 6/84 167/7206 0.0129877653866 ko05205 Proteoglycans in cancer 8/84 271/7206 0.013285750699 ko04912 GnRH signaling pathway 5/84 122/7206 0.01365845913 ko04130 SNARE interactions in vesicular transport 3/84 44/7206 0.0143519634489 ko05161 Hepatitis B 6/84 173/7206 0.0152419675341 ko05212 Pancreatic cancer 4/84 83/7206 0.0157265686552 ko04215 Apoptosis - multiple species 3/84 47/7206 0.0171395514403 ko05142 Chagas disease (American trypanosomiasis) 5/84 130/7206 0.0175537364958 ko04144 Endocytosis 9/84 342/7206 0.0175626361258 ko04213 Longevity regulating pathway - multiple species 4/84 86/7206 0.0177046950582 ko04657 IL-17 signaling pathway 4/84 87/7206 0.0183970329972 ko04380 Osteoclast differentiation 5/84 134/7206 0.0197525212914 ko05323 Rheumatoid arthritis 4/84 89/7206 0.019831819422 ko05222 Small cell lung cancer 4/84 89/7206 0.019831819422 ko04931 Insulin resistance 5/84 137/7206 0.0215157276222 ko05152 Tuberculosis 6/84 187/7206 0.0215340429802 ko05167 Kaposi's sarcoma-associated herpesvirus infection 6/84 191/7206 0.023613950643 ko05211 Renal cell carcinoma 4/84 96/7206 0.0253898896106 ko04658 Th1 and Th2 cell differentiation 4/84 96/7206 0.0253898896106 ko04064 NF-kappa B signaling pathway 4/84 96/7206 0.0253898896106 ko04650 Natural killer cell mediated cytotoxicity 4/84 97/7206 0.0262531317936 ko04620 Toll-like receptor signaling pathway 4/84 100/7206 0.0289482566941 ko05200 Pathways in cancer 11/84 492/7206 0.0293805916 ko04670 Leukocyte transendothelial migration 5/84 151/7206 0.0310949117938 ko04810 Regulation of actin cytoskeleton 7/84 264/7206 0.0337379298143 ko05221 Acute myeloid leukemia 3/84 63/7206 0.0367819467145 ko05414 Dilated cardiomyopathy 4/84 112/7206 0.0413318438613 ko04151 PI3K-Akt signaling pathway 9/84 390/7206 0.0460572806526