ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	66/705	152/7206	4.68734217257e-28
ko04080	Neuroactive ligand-receptor interaction	115/705	423/7206	2.45422607983e-26
ko05033	Nicotine addiction	37/705	56/7206	1.29936321348e-24
ko05032	Morphine addiction	52/705	110/7206	2.0004094586e-24
ko04727	GABAergic synapse	50/705	110/7206	1.46627423561e-22
ko04744	Phototransduction	27/705	36/7206	1.39996608406e-20
ko04723	Retrograde endocannabinoid signaling	56/705	175/7206	1.51693178072e-16
ko04713	Circadian entrainment	47/705	136/7206	1.6236417569e-15
ko04020	Calcium signaling pathway	63/705	265/7206	9.52291463633e-12
ko04728	Dopaminergic synapse	49/705	185/7206	3.44581205927e-11
ko04024	cAMP signaling pathway	61/705	279/7206	8.36439972224e-10
ko04725	Cholinergic synapse	41/705	160/7206	4.2338529271e-09
ko04742	Taste transduction	23/705	61/7206	4.37535496703e-09
ko04911	Insulin secretion	33/705	117/7206	1.10896462766e-08
ko04726	Serotonergic synapse	35/705	137/7206	6.39621855051e-08
ko05203	Viral carcinogenesis	5/705	277/7206	1.36266111326e-07
ko04721	Synaptic vesicle cycle	24/705	80/7206	3.22937701755e-07
ko04740	Olfactory transduction	24/705	80/7206	3.22937701755e-07
ko04720	Long-term potentiation	27/705	99/7206	5.10384371949e-07
ko04970	Salivary secretion	26/705	95/7206	7.70561022701e-07
ko04261	Adrenergic signaling in cardiomyocytes	43/705	205/7206	1.01836264186e-06
ko04921	Oxytocin signaling pathway	43/705	209/7206	2.2898791402e-06
ko05031	Amphetamine addiction	24/705	91/7206	4.18303305263e-06
ko04925	Aldosterone synthesis and secretion	26/705	105/7206	5.96073463552e-06
ko04072	Phospholipase D signaling pathway	40/705	197/7206	7.28928365886e-06
ko04010	MAPK signaling pathway	56/705	321/7206	1.25073248254e-05
ko05030	Cocaine addiction	20/705	73/7206	1.42516699968e-05
ko04070	Phosphatidylinositol signaling system	26/705	112/7206	2.95989461512e-05
ko03013	RNA transport	3/705	166/7206	8.94531736254e-05
ko04110	Cell cycle	2/705	145/7206	9.30802245953e-05
ko04972	Pancreatic secretion	24/705	111/7206	0.000151780426019
ko04022	cGMP-PKG signaling pathway	39/705	216/7206	0.000157434500549
ko04745	Phototransduction - fly	12/705	38/7206	0.000172655854849
ko04060	Cytokine-cytokine receptor interaction	5/705	191/7206	0.000175299761122
ko05205	Proteoglycans in cancer	10/705	271/7206	0.000225183295518
ko04710	Circadian rhythm	12/705	43/7206	0.000618787363125
ko04014	Ras signaling pathway	45/705	279/7206	0.000639823975114
ko04730	Long-term depression	17/705	78/7206	0.001484886644
ko04145	Phagosome	5/705	162/7206	0.00184496686518
ko05169	Epstein-Barr virus infection	8/705	206/7206	0.00188416635082
ko04810	Regulation of actin cytoskeleton	12/705	264/7206	0.00207952714678
ko05014	Amyotrophic lateral sclerosis (ALS)	16/705	74/7206	0.00224372357445
ko00230	Purine metabolism	32/705	194/7206	0.00298643185152
ko05162	Measles	3/705	120/7206	0.00302247122214
ko04971	Gastric acid secretion	19/705	98/7206	0.00311997761643
ko00562	Inositol phosphate metabolism	18/705	89/7206	0.00316432563305
ko05322	Systemic lupus erythematosus	5/705	151/7206	0.00349376785957
ko05168	Herpes simplex infection	7/705	182/7206	0.00350840001427
ko05164	Influenza A	6/705	167/7206	0.0035398309889
ko04750	Inflammatory mediator regulation of TRP channels	22/705	122/7206	0.00488972714423
ko04711	Circadian rhythm - fly	5/705	13/7206	0.00582974535992
ko04610	Complement and coagulation cascades	1/705	79/7206	0.00628875048565
ko04141	Protein processing in endoplasmic reticulum	8/705	184/7206	0.00813438944947
ko05202	Transcriptional misregulation in cancer	8/705	188/7206	0.00836205736558
ko04260	Cardiac muscle contraction	18/705	98/7206	0.00885451028576
ko04120	Ubiquitin mediated proteolysis	5/705	138/7206	0.00901881362138
ko05414	Dilated cardiomyopathy	20/705	112/7206	0.00909912716381
ko04540	Gap junction	22/705	128/7206	0.00962307735948
ko04514	Cell adhesion molecules (CAMs)	22/705	130/7206	0.010346628539
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	15/705	79/7206	0.0114595663099
ko04350	TGF-beta signaling pathway	3/705	103/7206	0.0118754230863
ko00601	Glycosphingolipid biosynthesis - lacto and neolacto series	7/705	28/7206	0.0158254555473
ko04657	IL-17 signaling pathway	2/705	87/7206	0.0161887558808
ko05133	Pertussis	2/705	87/7206	0.0161887558808
ko04620	Toll-like receptor signaling pathway	3/705	100/7206	0.0166406011619
ko04930	Type II diabetes mellitus	11/705	54/7206	0.0176778653256
ko04640	Hematopoietic cell lineage	1/705	64/7206	0.0187221039378
ko05224	Breast cancer	8/705	174/7206	0.0190860086323
ko04621	NOD-like receptor signaling pathway	7/705	157/7206	0.0202357714103
ko05131	Shigellosis	2/705	82/7206	0.022539992654
ko05145	Toxoplasmosis	5/705	126/7206	0.0225677736434
ko04932	Non-alcoholic fatty liver disease (NAFLD)	9/705	182/7206	0.0225707601598
ko04150	mTOR signaling pathway	9/705	184/7206	0.0227689701672
ko00240	Pyrimidine metabolism	4/705	110/7206	0.0231844301739
ko04658	Th1 and Th2 cell differentiation	3/705	96/7206	0.023225281216
ko00515	Mannose type O-glycan biosynthesis	6/705	25/7206	0.0301409569238
ko05130	Pathogenic Escherichia coli infection	2/705	77/7206	0.0314713437228
ko04550	Signaling pathways regulating pluripotency of stem cells	8/705	165/7206	0.0326249533054
ko05166	HTLV-I infection	18/705	292/7206	0.0341458128574
ko05034	Alcoholism	33/705	238/7206	0.035030332833
ko05161	Hepatitis B	9/705	173/7206	0.037850635779
ko04915	Estrogen signaling pathway	20/705	131/7206	0.0378770783618
ko04371	Apelin signaling pathway	26/705	177/7206	0.0389608796989
ko05416	Viral myocarditis	1/705	55/7206	0.0397235958478
ko00604	Glycosphingolipid biosynthesis - ganglio series	4/705	14/7206	0.0410115259065
ko00310	Lysine degradation	2/705	73/7206	0.0446223737891