ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04728	Dopaminergic synapse	43/505	185/7206	9.46334090643e-13
ko04721	Synaptic vesicle cycle	27/505	80/7206	1.5952537767e-12
ko05033	Nicotine addiction	22/505	56/7206	5.82185498882e-12
ko04727	GABAergic synapse	29/505	110/7206	2.22109125394e-10
ko04724	Glutamatergic synapse	34/505	152/7206	7.49941066403e-10
ko04360	Axon guidance	42/505	233/7206	8.31484962128e-09
ko05032	Morphine addiction	26/505	110/7206	2.34904376621e-08
ko04723	Retrograde endocannabinoid signaling	33/505	175/7206	1.16275739009e-07
ko04713	Circadian entrainment	26/505	136/7206	2.00566610919e-06
ko04514	Cell adhesion molecules (CAMs)	24/505	130/7206	9.32465654622e-06
ko05030	Cocaine addiction	16/505	73/7206	3.33972470007e-05
ko04725	Cholinergic synapse	26/505	160/7206	4.96547658253e-05
ko04391	Hippo signaling pathway - fly	17/505	90/7206	0.000139521977091
ko00230	Purine metabolism	2/505	194/7206	0.000154095587048
ko04911	Insulin secretion	20/505	117/7206	0.000157467771932
ko05203	Viral carcinogenesis	6/505	277/7206	0.000428481359455
ko03040	Spliceosome	1/505	145/7206	0.000457237496008
ko04950	Maturity onset diabetes of the young	8/505	29/7206	0.000633525009969
ko04024	cAMP signaling pathway	35/505	279/7206	0.000694755909546
ko04080	Neuroactive ligand-receptor interaction	48/505	423/7206	0.000768213290994
ko04611	Platelet activation	2/505	163/7206	0.000963117469831
ko04512	ECM-receptor interaction	14/505	79/7206	0.00103658946777
ko01200	Carbon metabolism	1/505	128/7206	0.00144717846599
ko05031	Amphetamine addiction	15/505	91/7206	0.00149992006576
ko04010	MAPK signaling pathway	38/505	321/7206	0.00155285453999
ko05014	Amyotrophic lateral sclerosis (ALS)	13/505	74/7206	0.00168499230103
ko04726	Serotonergic synapse	20/505	137/7206	0.00179058604977
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/505	14/7206	0.0019501969167
ko04060	Cytokine-cytokine receptor interaction	4/505	191/7206	0.00369991417799
ko03013	RNA transport	3/505	166/7206	0.00489536040211
ko04120	Ubiquitin mediated proteolysis	2/505	138/7206	0.00604948697825
ko04962	Vasopressin-regulated water reabsorption	10/505	58/7206	0.00643037061042
ko05168	Herpes simplex infection	4/505	182/7206	0.00727914835821
ko04550	Signaling pathways regulating pluripotency of stem cells	21/505	165/7206	0.00772178381569
ko05322	Systemic lupus erythematosus	3/505	151/7206	0.00928936619634
ko04912	GnRH signaling pathway	2/505	122/7206	0.0117807419954
ko04261	Adrenergic signaling in cardiomyocytes	24/505	205/7206	0.011815926574
ko05164	Influenza A	4/505	167/7206	0.0133789381251
ko04151	PI3K-Akt signaling pathway	40/505	390/7206	0.0139236438306
ko00603	Glycosphingolipid biosynthesis - globo and isoglobo series	3/505	8/7206	0.0146846848951
ko05224	Breast cancer	21/505	174/7206	0.0148021834686
ko05162	Measles	2/505	120/7206	0.0171491347797
ko05169	Epstein-Barr virus infection	6/505	206/7206	0.017503065495
ko04340	Hedgehog signaling pathway	9/505	58/7206	0.0185601767432
ko04146	Peroxisome	1/505	89/7206	0.0202939608791
ko04961	Endocrine and other factor-regulated calcium reabsorption	9/505	59/7206	0.0205920380569
ko04974	Protein digestion and absorption	13/505	96/7206	0.0233604409928
ko04217	Necroptosis	5/505	178/7206	0.0244139127591
ko04270	Vascular smooth muscle contraction	4/505	154/7206	0.0248690244839
ko00350	Tyrosine metabolism	6/505	33/7206	0.0251570368167
ko04621	NOD-like receptor signaling pathway	4/505	157/7206	0.0252699025943
ko04137	Mitophagy - animal	1/505	82/7206	0.0293821611158
ko03018	RNA degradation	1/505	84/7206	0.0295114119353
ko00190	Oxidative phosphorylation	3/505	127/7206	0.0342771356322
ko04330	Notch signaling pathway	9/505	62/7206	0.0384825422676
ko04141	Protein processing in endoplasmic reticulum	6/505	184/7206	0.0402227784204
ko03008	Ribosome biogenesis in eukaryotes	1/505	79/7206	0.0429463202295
ko00564	Glycerophospholipid metabolism	2/505	99/7206	0.0465306593348
ko05146	Amoebiasis	2/505	99/7206	0.0465306593348
ko04066	HIF-1 signaling pathway	3/505	123/7206	0.0476063791061