ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	163/971	423/7206	6.02743122283e-41
ko04724	Glutamatergic synapse	87/971	152/7206	8.60588099819e-38
ko04727	GABAergic synapse	64/971	110/7206	1.48344796601e-28
ko05032	Morphine addiction	64/971	110/7206	1.48344796601e-28
ko05033	Nicotine addiction	44/971	56/7206	2.33419801372e-28
ko04728	Dopaminergic synapse	84/971	185/7206	6.43354357215e-27
ko04713	Circadian entrainment	70/971	136/7206	1.07204620111e-26
ko04721	Synaptic vesicle cycle	48/971	80/7206	1.71445197205e-22
ko04723	Retrograde endocannabinoid signaling	75/971	175/7206	3.24538488752e-22
ko04725	Cholinergic synapse	68/971	160/7206	5.48359565378e-20
ko04911	Insulin secretion	54/971	117/7206	4.73705285804e-18
ko04024	cAMP signaling pathway	92/971	279/7206	1.23745529835e-17
ko04726	Serotonergic synapse	57/971	137/7206	2.02523153749e-16
ko05031	Amphetamine addiction	43/971	91/7206	4.40924327745e-15
ko04720	Long-term potentiation	45/971	99/7206	6.17179507992e-15
ko04921	Oxytocin signaling pathway	71/971	209/7206	1.31129648111e-14
ko04261	Adrenergic signaling in cardiomyocytes	69/971	205/7206	5.30987484687e-14
ko04020	Calcium signaling pathway	81/971	265/7206	1.44275673759e-13
ko04742	Taste transduction	31/971	61/7206	2.70523339279e-12
ko04744	Phototransduction	22/971	36/7206	3.29857066751e-11
ko04970	Salivary secretion	38/971	95/7206	9.41795183781e-11
ko04925	Aldosterone synthesis and secretion	40/971	105/7206	1.77794677567e-10
ko05030	Cocaine addiction	30/971	73/7206	4.25470100148e-09
ko04060	Cytokine-cytokine receptor interaction	3/971	191/7206	5.23665952551e-09
ko04971	Gastric acid secretion	35/971	98/7206	1.77727099513e-08
ko03040	Spliceosome	1/971	145/7206	2.29970218416e-08
ko04010	MAPK signaling pathway	78/971	321/7206	9.07173585582e-08
ko04022	cGMP-PKG signaling pathway	57/971	216/7206	2.63004332834e-07
ko04730	Long-term depression	28/971	78/7206	4.22345553649e-07
ko04972	Pancreatic secretion	35/971	111/7206	6.92372630574e-07
ko04072	Phospholipase D signaling pathway	51/971	197/7206	2.21519292307e-06
ko04745	Phototransduction - fly	17/971	38/7206	2.46283675073e-06
ko04740	Olfactory transduction	27/971	80/7206	2.71370266993e-06
ko04070	Phosphatidylinositol signaling system	34/971	112/7206	3.78632003798e-06
ko05168	Herpes simplex infection	6/971	182/7206	4.50907827949e-06
ko05203	Viral carcinogenesis	14/971	277/7206	5.59946705819e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	25/971	74/7206	6.20342423194e-06
ko04966	Collecting duct acid secretion	13/971	26/7206	8.47788106067e-06
ko05110	Vibrio cholerae infection	22/971	63/7206	1.21882778114e-05
ko04915	Estrogen signaling pathway	36/971	131/7206	2.27835220863e-05
ko05322	Systemic lupus erythematosus	5/971	151/7206	3.26793156748e-05
ko04961	Endocrine and other factor-regulated calcium reabsorption	20/971	59/7206	4.92895037819e-05
ko04540	Gap junction	34/971	128/7206	6.56301020214e-05
ko04260	Cardiac muscle contraction	28/971	98/7206	7.0599990902e-05
ko04371	Apelin signaling pathway	43/971	177/7206	7.85603955093e-05
ko04360	Axon guidance	53/971	233/7206	8.27413714906e-05
ko03013	RNA transport	7/971	166/7206	0.000118465296662
ko04912	GnRH signaling pathway	32/971	122/7206	0.000139775756242
ko04514	Cell adhesion molecules (CAMs)	33/971	130/7206	0.000227295093411
ko04110	Cell cycle	6/971	145/7206	0.000302744331074
ko04014	Ras signaling pathway	59/971	279/7206	0.000315404374789
ko04621	NOD-like receptor signaling pathway	7/971	157/7206	0.00032496332329
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	23/971	79/7206	0.000334120151536
ko05414	Dilated cardiomyopathy	29/971	112/7206	0.000385915036505
ko04750	Inflammatory mediator regulation of TRP channels	31/971	122/7206	0.000397437641936
ko00240	Pyrimidine metabolism	4/971	110/7206	0.00100754805459
ko05162	Measles	5/971	120/7206	0.00108102096844
ko04924	Renin secretion	23/971	86/7206	0.00113948279439
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/971	14/7206	0.00114213830031
ko05164	Influenza A	9/971	167/7206	0.00116994511601
ko05169	Epstein-Barr virus infection	13/971	206/7206	0.00124689788068
ko04626	Plant-pathogen interaction	8/971	18/7206	0.001321067546
ko04141	Protein processing in endoplasmic reticulum	11/971	184/7206	0.00140884390526
ko03008	Ribosome biogenesis in eukaryotes	2/971	79/7206	0.00144778876838
ko04612	Antigen processing and presentation	2/971	77/7206	0.00212399817867
ko04918	Thyroid hormone synthesis	22/971	86/7206	0.00221826583533
ko04330	Notch signaling pathway	1/971	62/7206	0.00229628110199
ko04922	Glucagon signaling pathway	30/971	128/7206	0.00232821539147
ko05034	Alcoholism	48/971	238/7206	0.00358577298822
ko04064	NF-kappa B signaling pathway	4/971	96/7206	0.00394213686667
ko04976	Bile secretion	20/971	80/7206	0.00467307127573
ko00480	Glutathione metabolism	1/971	55/7206	0.00507314495906
ko04120	Ubiquitin mediated proteolysis	8/971	138/7206	0.00529698605693
ko05410	Hypertrophic cardiomyopathy (HCM)	23/971	100/7206	0.00771594443452
ko00562	Inositol phosphate metabolism	21/971	89/7206	0.00772742550467
ko04350	TGF-beta signaling pathway	5/971	103/7206	0.00807069430323
ko04640	Hematopoietic cell lineage	2/971	64/7206	0.00936832969356
ko04630	Jak-STAT signaling pathway	8/971	132/7206	0.00954474642613
ko05231	Choline metabolism in cancer	29/971	134/7206	0.00991304296521
ko05140	Leishmaniasis	3/971	75/7206	0.0103782246877
ko01524	Platinum drug resistance	3/971	76/7206	0.0104242689721
ko05222	Small cell lung cancer	4/971	89/7206	0.0112541035161
ko04964	Proximal tubule bicarbonate reclamation	9/971	29/7206	0.0113599444521
ko04062	Chemokine signaling pathway	40/971	201/7206	0.0114171763173
ko05214	Glioma	19/971	79/7206	0.0115305384624
ko04015	Rap1 signaling pathway	52/971	278/7206	0.0119309291632
ko04916	Melanogenesis	30/971	142/7206	0.012279029182
ko05120	Epithelial cell signaling in Helicobacter pylori infection	21/971	92/7206	0.0130406927485
ko04217	Necroptosis	13/971	178/7206	0.0139005297519
ko04214	Apoptosis - fly	3/971	72/7206	0.0146517615045
ko00310	Lysine degradation	3/971	73/7206	0.014746906446
ko03018	RNA degradation	4/971	84/7206	0.0150332321569
ko04510	Focal adhesion	20/971	240/7206	0.0159721206863
ko04114	Oocyte meiosis	29/971	139/7206	0.0162729346482
ko03420	Nucleotide excision repair	1/971	46/7206	0.0165246136253
ko05145	Toxoplasmosis	8/971	126/7206	0.0169735964657
ko05204	Chemical carcinogenesis	1/971	48/7206	0.0171166968493
ko04960	Aldosterone-regulated sodium reabsorption	11/971	41/7206	0.019612492478
ko03320	PPAR signaling pathway	3/971	69/7206	0.0206194065984
ko04270	Vascular smooth muscle contraction	31/971	154/7206	0.0224839959777
ko04973	Carbohydrate digestion and absorption	11/971	42/7206	0.022576590386
ko05205	Proteoglycans in cancer	24/971	271/7206	0.0230096814831
ko03022	Basal transcription factors	1/971	44/7206	0.0246096151791
ko04071	Sphingolipid signaling pathway	32/971	162/7206	0.0260983658421
ko04146	Peroxisome	5/971	89/7206	0.027581658916
ko05321	Inflammatory bowel disease (IBD)	2/971	56/7206	0.0283512798247
ko04658	Th1 and Th2 cell differentiation	6/971	96/7206	0.0346067584241
ko00140	Steroid hormone biosynthesis	1/971	41/7206	0.0363258756106
ko04550	Signaling pathways regulating pluripotency of stem cells	13/971	165/7206	0.0368957698959
ko04657	IL-17 signaling pathway	5/971	87/7206	0.0380447508508
ko04115	p53 signaling pathway	4/971	74/7206	0.0392169631535
ko04622	RIG-I-like receptor signaling pathway	3/971	62/7206	0.0404123424932
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	5/971	15/7206	0.0412678697265
ko05418	Fluid shear stress and atherosclerosis	14/971	173/7206	0.0414663595482
ko05161	Hepatitis B	14/971	173/7206	0.0414663595482
ko04923	Regulation of lipolysis in adipocytes	17/971	77/7206	0.0415476315892
ko04930	Type II diabetes mellitus	13/971	54/7206	0.0418772508623
ko05016	Huntington's disease	19/971	215/7206	0.0424239218178
ko05010	Alzheimer's disease	37/971	202/7206	0.0466730700282
ko04012	ErbB signaling pathway	22/971	109/7206	0.0468740455599
ko00512	Mucin type O-glycan biosynthesis	8/971	29/7206	0.0484541872825
ko05215	Prostate cancer	8/971	111/7206	0.0498798998087