ko pathway ratio_in_study ratio_in_pop p_value ko00260 Glycine, serine and threonine metabolism 9/64 48/7206 2.45583904633e-10 ko02010 ABC transporters 7/64 39/7206 3.83203046377e-08 ko04146 Peroxisome 8/64 89/7206 9.91258234546e-07 ko01200 Carbon metabolism 8/64 128/7206 1.52956024994e-05 ko00250 Alanine, aspartate and glutamate metabolism 5/64 38/7206 1.88850240952e-05 ko04610 Complement and coagulation cascades 6/64 79/7206 6.4794919614e-05 ko04976 Bile secretion 6/64 80/7206 6.9566054781e-05 ko00680 Methane metabolism 4/64 34/7206 0.000214886393192 ko04614 Renin-angiotensin system 3/64 18/7206 0.000495775370067 ko00220 Arginine biosynthesis 3/64 24/7206 0.00118384766899 ko00982 Drug metabolism - cytochrome P450 3/64 37/7206 0.00418649135966 ko00630 Glyoxylate and dicarboxylate metabolism 3/64 38/7206 0.00451678650473 ko00983 Drug metabolism - other enzymes 3/64 42/7206 0.00599376459955 ko01230 Biosynthesis of amino acids 4/64 85/7206 0.00669351025723 ko05204 Chemical carcinogenesis 3/64 48/7206 0.00869620152508 ko00360 Phenylalanine metabolism 2/64 17/7206 0.00969193634952 ko00380 Tryptophan metabolism 3/64 50/7206 0.00973172478985 ko00590 Arachidonic acid metabolism 3/64 52/7206 0.0108362689171 ko01210 2-Oxocarboxylic acid metabolism 2/64 20/7206 0.0133107855259 ko04977 Vitamin digestion and absorption 2/64 22/7206 0.0160000867255 ko00330 Arginine and proline metabolism 3/64 61/7206 0.0166805476516 ko00340 Histidine metabolism 2/64 25/7206 0.0204283854901 ko00650 Butanoate metabolism 2/64 26/7206 0.0220056151399 ko03320 PPAR signaling pathway 3/64 69/7206 0.0231013342108 ko00633 Nitrotoluene degradation 1/64 3/7206 0.0264121540464 ko05142 Chagas disease (American trypanosomiasis) 4/64 130/7206 0.0279599187624 ko01523 Antifolate resistance 2/64 30/7206 0.0287942005471 ko01524 Platinum drug resistance 3/64 76/7206 0.0296756891469 ko00030 Pentose phosphate pathway 2/64 32/7206 0.0324631001743 ko00350 Tyrosine metabolism 2/64 33/7206 0.0343629908334 ko00471 D-Glutamine and D-glutamate metabolism 1/64 4/7206 0.0350626638535 ko00290 Valine, leucine and isoleucine biosynthesis 1/64 4/7206 0.0350626638535 ko00860 Porphyrin and chlorophyll metabolism 2/64 34/7206 0.0363053181443 ko04975 Fat digestion and absorption 2/64 35/7206 0.0382892041493 ko00472 D-Arginine and D-ornithine metabolism 1/64 5/7206 0.0436375027197 ko00232 Caffeine metabolism 1/64 5/7206 0.0436375027197 ko00311 Penicillin and cephalosporin biosynthesis 1/64 5/7206 0.0436375027197 ko00980 Metabolism of xenobiotics by cytochrome P450 2/64 40/7206 0.0488021056448