ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 15/133 191/7206 2.01891724857e-06 ko04072 Phospholipase D signaling pathway 14/133 197/7206 1.43896091531e-05 ko04068 FoxO signaling pathway 12/133 167/7206 5.46056554125e-05 ko05231 Choline metabolism in cancer 10/133 134/7206 0.00017110031352 ko04933 AGE-RAGE signaling pathway in diabetic complications 10/133 135/7206 0.000181927252149 ko04070 Phosphatidylinositol signaling system 9/133 112/7206 0.000208970358813 ko05164 Influenza A 11/133 167/7206 0.000244154985383 ko04672 Intestinal immune network for IgA production 5/133 37/7206 0.000538770452276 ko04014 Ras signaling pathway 14/133 279/7206 0.000597173340451 ko05214 Glioma 7/133 79/7206 0.0005980720965 ko05230 Central carbon metabolism in cancer 7/133 81/7206 0.000695857178295 ko05167 Kaposi's sarcoma-associated herpesvirus infection 11/133 191/7206 0.000767104956065 ko04380 Osteoclast differentiation 9/133 134/7206 0.000788585071517 ko05212 Pancreatic cancer 7/133 83/7206 0.000805913542009 ko05220 Chronic myeloid leukemia 7/133 85/7206 0.000929303883627 ko05166 HTLV-I infection 14/133 292/7206 0.000935002878061 ko05215 Prostate cancer 8/133 111/7206 0.000977548073783 ko04144 Endocytosis 15/133 342/7206 0.00151437138108 ko05162 Measles 8/133 120/7206 0.00161990018524 ko04015 Rap1 signaling pathway 13/133 278/7206 0.00178766794122 ko04066 HIF-1 signaling pathway 8/133 123/7206 0.00189600754145 ko01522 Endocrine resistance 8/133 124/7206 0.00199587517925 ko04650 Natural killer cell mediated cytotoxicity 7/133 97/7206 0.00201475427059 ko04071 Sphingolipid signaling pathway 9/133 162/7206 0.00296022283445 ko01521 EGFR tyrosine kinase inhibitor resistance 7/133 106/7206 0.00333365620629 ko04012 ErbB signaling pathway 7/133 109/7206 0.00389462110883 ko05210 Colorectal cancer 6/133 86/7206 0.00496519290013 ko04917 Prolactin signaling pathway 6/133 87/7206 0.00525393781236 ko04218 Cellular senescence 9/133 177/7206 0.00531318263607 ko04662 B cell receptor signaling pathway 6/133 88/7206 0.00555482394163 ko04912 GnRH signaling pathway 7/133 122/7206 0.00719050021881 ko04750 Inflammatory mediator regulation of TRP channels 7/133 122/7206 0.00719050021881 ko05223 Non-small cell lung cancer 5/133 66/7206 0.00721581477967 ko04064 NF-kappa B signaling pathway 6/133 96/7206 0.0084339955737 ko05145 Toxoplasmosis 7/133 126/7206 0.00853172708585 ko04722 Neurotrophin signaling pathway 8/133 160/7206 0.0093157858114 ko04620 Toll-like receptor signaling pathway 6/133 100/7206 0.0102182870102 ko01524 Platinum drug resistance 5/133 76/7206 0.0128949678764 ko05200 Pathways in cancer 17/133 492/7206 0.0132516700121 ko04370 VEGF signaling pathway 5/133 77/7206 0.0135915176558 ko04664 Fc epsilon RI signaling pathway 5/133 77/7206 0.0135915176558 ko05418 Fluid shear stress and atherosclerosis 8/133 173/7206 0.0144697641137 ko05161 Hepatitis B 8/133 173/7206 0.0144697641137 ko04610 Complement and coagulation cascades 5/133 79/7206 0.0150599123181 ko05206 MicroRNAs in cancer 8/133 177/7206 0.0164089556094 ko05205 Proteoglycans in cancer 11/133 271/7206 0.0171067573612 ko05218 Melanoma 5/133 85/7206 0.0200928242371 ko05152 Tuberculosis 8/133 187/7206 0.0220709406815 ko00562 Inositol phosphate metabolism 5/133 89/7206 0.0239968159434 ko04660 T cell receptor signaling pathway 6/133 124/7206 0.0268281065185 ko05213 Endometrial cancer 4/133 62/7206 0.0271485687502 ko04725 Cholinergic synapse 7/133 160/7206 0.0282527328611 ko04540 Gap junction 6/133 128/7206 0.0307193165097 ko04611 Platelet activation 7/133 163/7206 0.0308400541414 ko04020 Calcium signaling pathway 10/133 265/7206 0.0308872850111 ko04140 Autophagy - animal 7/133 164/7206 0.0317368775109 ko05211 Renal cell carcinoma 5/133 96/7206 0.0319440259646 ko05142 Chagas disease (American trypanosomiasis) 6/133 130/7206 0.0327968713947 ko04630 Jak-STAT signaling pathway 6/133 132/7206 0.0349640154719 ko05146 Amoebiasis 5/133 99/7206 0.0357995403971 ko00254 Aflatoxin biosynthesis 1/133 2/7206 0.0365755424343 ko04960 Aldosterone-regulated sodium reabsorption 3/133 41/7206 0.0393706093427 ko00140 Steroid hormone biosynthesis 3/133 41/7206 0.0393706093427 ko04931 Insulin resistance 6/133 137/7206 0.0407808335112 ko00051 Fructose and mannose metabolism 3/133 42/7206 0.0418440650354 ko04973 Carbohydrate digestion and absorption 3/133 42/7206 0.0418440650354 ko04919 Thyroid hormone signaling pathway 6/133 143/7206 0.0485292463511 ko05140 Leishmaniasis 4/133 75/7206 0.0493679171534