ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 29/182 191/7206 2.64302094605e-15 ko04650 Natural killer cell mediated cytotoxicity 19/182 97/7206 2.17233101557e-12 ko04380 Osteoclast differentiation 21/182 134/7206 1.31217741881e-11 ko05145 Toxoplasmosis 19/182 126/7206 2.61889681967e-10 ko04659 Th17 cell differentiation 17/182 106/7206 9.01758274358e-10 ko05340 Primary immunodeficiency 10/182 30/7206 1.60049060015e-09 ko05140 Leishmaniasis 14/182 75/7206 3.80483694806e-09 ko04064 NF-kappa B signaling pathway 15/182 96/7206 1.33553661136e-08 ko04062 Chemokine signaling pathway 21/182 201/7206 2.67624429063e-08 ko04658 Th1 and Th2 cell differentiation 14/182 96/7206 1.0215292428e-07 ko05321 Inflammatory bowel disease (IBD) 11/182 56/7206 1.09242151199e-07 ko05152 Tuberculosis 19/182 187/7206 2.01031505206e-07 ko04660 T cell receptor signaling pathway 15/182 124/7206 4.38903502742e-07 ko04630 Jak-STAT signaling pathway 15/182 132/7206 9.93246863027e-07 ko04621 NOD-like receptor signaling pathway 16/182 157/7206 1.86769657497e-06 ko04217 Necroptosis 17/182 178/7206 2.17972279391e-06 ko04612 Antigen processing and presentation 11/182 77/7206 3.09009028137e-06 ko04664 Fc epsilon RI signaling pathway 11/182 77/7206 3.09009028137e-06 ko05164 Influenza A 16/182 167/7206 4.22365941623e-06 ko05162 Measles 13/182 120/7206 9.17004112443e-06 ko04662 B cell receptor signaling pathway 11/182 88/7206 1.16266249669e-05 ko05330 Allograft rejection 6/182 24/7206 2.20285373547e-05 ko05167 Kaposi's sarcoma-associated herpesvirus infection 16/182 191/7206 2.34487123812e-05 ko04620 Toll-like receptor signaling pathway 11/182 100/7206 3.95440851045e-05 ko04666 Fc gamma R-mediated phagocytosis 12/182 122/7206 5.40132590274e-05 ko04611 Platelet activation 14/182 163/7206 5.87293297689e-05 ko04670 Leukocyte transendothelial migration 13/182 151/7206 0.000105910411512 ko05144 Malaria 7/182 45/7206 0.000117714008306 ko04145 Phagosome 13/182 162/7206 0.000215217832861 ko04672 Intestinal immune network for IgA production 6/182 37/7206 0.000289600167527 ko05168 Herpes simplex infection 13/182 182/7206 0.000665666041816 ko05169 Epstein-Barr virus infection 14/182 206/7206 0.000682297633618 ko05320 Autoimmune thyroid disease 5/182 29/7206 0.000705695112209 ko05310 Asthma 4/182 17/7206 0.000724091898905 ko05132 Salmonella infection 9/182 98/7206 0.000780747982464 ko05146 Amoebiasis 9/182 99/7206 0.000840474913074 ko05332 Graft-versus-host disease 4/182 18/7206 0.000912747287165 ko04640 Hematopoietic cell lineage 7/182 64/7206 0.00107642689983 ko05323 Rheumatoid arthritis 8/182 89/7206 0.00175150142951 ko03050 Proteasome 6/182 54/7206 0.00225638290152 ko05416 Viral myocarditis 6/182 55/7206 0.00248056564 ko00051 Fructose and mannose metabolism 5/182 42/7206 0.00387908333141 ko05133 Pertussis 7/182 87/7206 0.00623362637374 ko04933 AGE-RAGE signaling pathway in diabetic complications 9/182 135/7206 0.00699544034276 ko04940 Type I diabetes mellitus 4/182 32/7206 0.00814621889148 ko04750 Inflammatory mediator regulation of TRP channels 8/182 122/7206 0.0118358532146 ko05142 Chagas disease (American trypanosomiasis) 8/182 130/7206 0.0168586883936 ko04514 Cell adhesion molecules (CAMs) 8/182 130/7206 0.0168586883936 ko04072 Phospholipase D signaling pathway 11/182 197/7206 0.0170522872928 ko05166 HTLV-I infection 14/182 292/7206 0.019957661498 ko05034 Alcoholism 1/182 238/7206 0.0322439073446 ko04066 HIF-1 signaling pathway 7/182 123/7206 0.0357663102904 ko00590 Arachidonic acid metabolism 4/182 52/7206 0.0416378312289 ko05161 Hepatitis B 9/182 173/7206 0.0421585420872 ko01524 Platinum drug resistance 5/182 76/7206 0.0425819488957