ko pathway ratio_in_study ratio_in_pop p_value ko04621 NOD-like receptor signaling pathway 11/60 157/7206 5.051044831e-08 ko05152 Tuberculosis 10/60 187/7206 2.66099344499e-06 ko04668 TNF signaling pathway 8/60 120/7206 5.80791121022e-06 ko05168 Herpes simplex infection 9/60 182/7206 1.67108490578e-05 ko04620 Toll-like receptor signaling pathway 7/60 100/7206 1.69734074172e-05 ko05131 Shigellosis 6/60 82/7206 5.53538037388e-05 ko04217 Necroptosis 8/60 178/7206 0.00010117087623 ko04210 Apoptosis 8/60 180/7206 0.000109402771017 ko04380 Osteoclast differentiation 7/60 134/7206 0.000111688685383 ko05167 Kaposi's sarcoma-associated herpesvirus infection 8/60 191/7206 0.00016525509782 ko05161 Hepatitis B 7/60 173/7206 0.000538025781626 ko04660 T cell receptor signaling pathway 6/60 124/7206 0.000538752848159 ko05321 Inflammatory bowel disease (IBD) 4/60 56/7206 0.00115487389104 ko04658 Th1 and Th2 cell differentiation 5/60 96/7206 0.00115699810271 ko05160 Hepatitis C 6/60 153/7206 0.00161557367078 ko04622 RIG-I-like receptor signaling pathway 4/60 62/7206 0.00169012960002 ko04071 Sphingolipid signaling pathway 6/60 162/7206 0.00216073882215 ko05145 Toxoplasmosis 5/60 126/7206 0.0038232865625 ko04662 B cell receptor signaling pathway 4/60 88/7206 0.00601818856267 ko04215 Apoptosis - multiple species 3/60 47/7206 0.00686160331518 ko04064 NF-kappa B signaling pathway 4/60 96/7206 0.00816187257568 ko05100 Bacterial invasion of epithelial cells 4/60 99/7206 0.00908000504237 ko04611 Platelet activation 5/60 163/7206 0.0111731099735 ko05164 Influenza A 5/60 167/7206 0.0123179751934 ko05418 Fluid shear stress and atherosclerosis 5/60 173/7206 0.014181504467 ko04010 MAPK signaling pathway 7/60 321/7206 0.0165800362501 ko00073 Cutin, suberine and wax biosynthesis 1/60 2/7206 0.0165846065132 ko04932 Non-alcoholic fatty liver disease (NAFLD) 5/60 182/7206 0.0173204900573 ko01522 Endocrine resistance 4/60 124/7206 0.0194158085372 ko04060 Cytokine-cytokine receptor interaction 5/60 191/7206 0.020892515402 ko05142 Chagas disease (American trypanosomiasis) 4/60 130/7206 0.0226632429159 ko04072 Phospholipase D signaling pathway 5/60 197/7206 0.0235248558021 ko04630 Jak-STAT signaling pathway 4/60 132/7206 0.0238152650383 ko01524 Platinum drug resistance 3/60 76/7206 0.0251094883544 ko05130 Pathogenic Escherichia coli infection 3/60 77/7206 0.0259759242131 ko04931 Insulin resistance 4/60 137/7206 0.0268497241236 ko04320 Dorso-ventral axis formation 2/60 31/7206 0.0271580108863 ko05212 Pancreatic cancer 3/60 83/7206 0.0315098171496 ko05166 HTLV-I infection 6/60 292/7206 0.0336745923112 ko04657 IL-17 signaling pathway 3/60 87/7206 0.0355166873823 ko04920 Adipocytokine signaling pathway 3/60 89/7206 0.037614615465 ko00562 Inositol phosphate metabolism 3/60 89/7206 0.037614615465 ko05222 Small cell lung cancer 3/60 89/7206 0.037614615465 ko05120 Epithelial cell signaling in Helicobacter pylori infection 3/60 92/7206 0.0408786505991 ko05132 Salmonella infection 3/60 98/7206 0.0478232255817