ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko03040	Spliceosome	88/680	145/7206	2.2685156944e-54
ko04110	Cell cycle	66/680	145/7206	1.65251682913e-30
ko04111	Cell cycle - yeast	47/680	90/7206	2.87348360855e-25
ko03030	DNA replication	28/680	38/7206	2.23273899705e-21
ko03013	RNA transport	56/680	166/7206	1.83992485876e-18
ko04113	Meiosis - yeast	33/680	70/7206	2.42957871479e-16
ko03015	mRNA surveillance pathway	35/680	93/7206	1.37080807054e-13
ko03410	Base excision repair	21/680	38/7206	1.35323703234e-12
ko03430	Mismatch repair	16/680	22/7206	1.45560078023e-12
ko03420	Nucleotide excision repair	23/680	46/7206	1.87199696306e-12
ko03460	Fanconi anemia pathway	24/680	51/7206	3.30499537659e-12
ko00240	Pyrimidine metabolism	35/680	110/7206	3.74490101014e-11
ko04020	Calcium signaling pathway	1/680	265/7206	1.22694408661e-10
ko04144	Endocytosis	4/680	342/7206	1.32968459566e-10
ko03008	Ribosome biogenesis in eukaryotes	28/680	79/7206	2.07206505125e-10
ko03440	Homologous recombination	18/680	41/7206	7.12203979273e-09
ko03022	Basal transcription factors	17/680	44/7206	1.83319519863e-07
ko04060	Cytokine-cytokine receptor interaction	1/680	191/7206	2.11012287952e-07
ko04921	Oxytocin signaling pathway	2/680	209/7206	4.11792586336e-07
ko04932	Non-alcoholic fatty liver disease (NAFLD)	1/680	182/7206	4.6552215693e-07
ko04723	Retrograde endocannabinoid signaling	1/680	175/7206	1.1019727907e-06
ko04072	Phospholipase D signaling pathway	2/680	197/7206	1.36988848033e-06
ko03018	RNA degradation	23/680	84/7206	1.7764170206e-06
ko05012	Parkinson's disease	1/680	155/7206	5.0933119538e-06
ko04024	cAMP signaling pathway	7/680	279/7206	5.26585599776e-06
ko04062	Chemokine signaling pathway	3/680	201/7206	6.5630473557e-06
ko04022	cGMP-PKG signaling pathway	4/680	216/7206	8.67472686805e-06
ko04120	Ubiquitin mediated proteolysis	30/680	138/7206	1.05132688237e-05
ko05166	HTLV-I infection	51/680	292/7206	1.31329464977e-05
ko04014	Ras signaling pathway	8/680	279/7206	2.28405714489e-05
ko04725	Cholinergic synapse	2/680	160/7206	2.87804774594e-05
ko03020	RNA polymerase	11/680	29/7206	3.44457293963e-05
ko05217	Basal cell carcinoma	18/680	68/7206	3.88214009673e-05
ko04621	NOD-like receptor signaling pathway	2/680	157/7206	4.25786856901e-05
ko03010	Ribosome	1/680	129/7206	5.58637693415e-05
ko04270	Vascular smooth muscle contraction	2/680	154/7206	6.40976661703e-05
ko04015	Rap1 signaling pathway	9/680	278/7206	8.87722345752e-05
ko04114	Oocyte meiosis	28/680	139/7206	9.45579962917e-05
ko04261	Adrenergic signaling in cardiomyocytes	5/680	205/7206	0.00013252201138
ko04151	PI3K-Akt signaling pathway	17/680	390/7206	0.000165938819217
ko04071	Sphingolipid signaling pathway	3/680	162/7206	0.000182505432926
ko04371	Apelin signaling pathway	4/680	177/7206	0.0002189628721
ko04810	Regulation of actin cytoskeleton	9/680	264/7206	0.000226311183298
ko04010	MAPK signaling pathway	13/680	321/7206	0.00027636161532
ko05160	Hepatitis C	3/680	153/7206	0.000373589031423
ko05032	Morphine addiction	1/680	110/7206	0.000405442705134
ko05142	Chagas disease (American trypanosomiasis)	2/680	130/7206	0.000407145954197
ko04915	Estrogen signaling pathway	2/680	131/7206	0.000409324645149
ko04972	Pancreatic secretion	1/680	111/7206	0.000415814486296
ko04510	Focal adhesion	8/680	240/7206	0.000424895133817
ko05414	Dilated cardiomyopathy	1/680	112/7206	0.000431670383195
ko04330	Notch signaling pathway	15/680	62/7206	0.000492565594365
ko04728	Dopaminergic synapse	5/680	185/7206	0.000495607869203
ko04611	Platelet activation	4/680	163/7206	0.000620747244318
ko00230	Purine metabolism	33/680	194/7206	0.000694151119257
ko04912	GnRH signaling pathway	2/680	122/7206	0.000858397468898
ko05410	Hypertrophic cardiomyopathy (HCM)	1/680	100/7206	0.000872986576977
ko04620	Toll-like receptor signaling pathway	1/680	100/7206	0.000872986576977
ko04722	Neurotrophin signaling pathway	4/680	160/7206	0.00087971644466
ko04914	Progesterone-mediated oocyte maturation	21/680	104/7206	0.000961028988724
ko04650	Natural killer cell mediated cytotoxicity	1/680	97/7206	0.0013002384147
ko05132	Salmonella infection	1/680	98/7206	0.00132769989813
ko05146	Amoebiasis	1/680	99/7206	0.00137151814611
ko04380	Osteoclast differentiation	3/680	134/7206	0.00152564627908
ko05231	Choline metabolism in cancer	3/680	134/7206	0.00152564627908
ko04933	AGE-RAGE signaling pathway in diabetic complications	3/680	135/7206	0.00153681961333
ko04713	Circadian entrainment	3/680	136/7206	0.00156116113608
ko04712	Circadian rhythm - plant	4/680	7/7206	0.00218019646625
ko05169	Epstein-Barr virus infection	33/680	206/7206	0.00227084199343
ko04340	Hedgehog signaling pathway	13/680	58/7206	0.00242480559325
ko04070	Phosphatidylinositol signaling system	2/680	112/7206	0.00274346883886
ko05133	Pertussis	1/680	87/7206	0.00279490456963
ko04146	Peroxisome	1/680	89/7206	0.00284541851512
ko05145	Toxoplasmosis	3/680	126/7206	0.00308193858458
ko04668	TNF signaling pathway	3/680	120/7206	0.00433398874716
ko04750	Inflammatory mediator regulation of TRP channels	3/680	122/7206	0.00437183374718
ko05168	Herpes simplex infection	29/680	182/7206	0.00440527081047
ko04910	Insulin signaling pathway	6/680	172/7206	0.00503274895359
ko04976	Bile secretion	1/680	80/7206	0.00608892812057
ko04740	Olfactory transduction	1/680	80/7206	0.00608892812057
ko04911	Insulin secretion	3/680	117/7206	0.00612389676901
ko04670	Leukocyte transendothelial migration	5/680	151/7206	0.00682377044502
ko05100	Bacterial invasion of epithelial cells	2/680	99/7206	0.0080859248346
ko05140	Leishmaniasis	1/680	75/7206	0.00885648649465
ko04540	Gap junction	4/680	128/7206	0.00902415860761
ko04923	Regulation of lipolysis in adipocytes	1/680	77/7206	0.00916575242407
ko04514	Cell adhesion molecules (CAMs)	4/680	130/7206	0.00917299029673
ko05152	Tuberculosis	8/680	187/7206	0.0109005851718
ko05120	Epithelial cell signaling in Helicobacter pylori infection	2/680	92/7206	0.0109534085305
ko04660	T cell receptor signaling pathway	4/680	124/7206	0.0124656078695
ko04310	Wnt signaling pathway	27/680	181/7206	0.0142490366031
ko04530	Tight junction	11/680	228/7206	0.0149144839353
ko04924	Renin secretion	2/680	86/7206	0.0155447545353
ko00562	Inositol phosphate metabolism	2/680	89/7206	0.0159115359264
ko04925	Aldosterone synthesis and secretion	3/680	105/7206	0.0170645864611
ko04931	Insulin resistance	5/680	137/7206	0.0170900801559
ko04659	Th17 cell differentiation	3/680	106/7206	0.0173788177805
ko04217	Necroptosis	8/680	178/7206	0.018954759786
ko04139	Mitophagy - yeast	8/680	37/7206	0.0197960247984
ko04630	Jak-STAT signaling pathway	5/680	132/7206	0.0229754482996
ko04720	Long-term potentiation	3/680	99/7206	0.0233723748338
ko00564	Glycerophospholipid metabolism	3/680	99/7206	0.0233723748338
ko04622	RIG-I-like receptor signaling pathway	1/680	62/7206	0.0275904799295
ko05110	Vibrio cholerae infection	1/680	63/7206	0.0278795381715
ko00561	Glycerolipid metabolism	1/680	63/7206	0.0278795381715
ko00600	Sphingolipid metabolism	1/680	63/7206	0.0278795381715
ko04640	Hematopoietic cell lineage	1/680	64/7206	0.0284277559167
ko04141	Protein processing in endoplasmic reticulum	9/680	184/7206	0.0295258005998
ko04550	Signaling pathways regulating pluripotency of stem cells	24/680	165/7206	0.0301898314498
ko01200	Carbon metabolism	5/680	128/7206	0.0310910580938
ko03050	Proteasome	10/680	54/7206	0.0322965749116
ko05230	Central carbon metabolism in cancer	2/680	81/7206	0.0324861059222
ko05030	Cocaine addiction	2/680	73/7206	0.0440863310927
ko05031	Amphetamine addiction	3/680	91/7206	0.0450421514639
ko04370	VEGF signaling pathway	2/680	77/7206	0.0462156217732
ko04664	Fc epsilon RI signaling pathway	2/680	77/7206	0.0462156217732