ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	81/397	423/7206	1.03097482017e-24
ko04724	Glutamatergic synapse	47/397	152/7206	1.21822110461e-23
ko05033	Nicotine addiction	26/397	56/7206	1.20711788445e-18
ko04728	Dopaminergic synapse	40/397	185/7206	2.78264314889e-14
ko04727	GABAergic synapse	30/397	110/7206	8.40606048886e-14
ko04713	Circadian entrainment	33/397	136/7206	1.7926413622e-13
ko05032	Morphine addiction	29/397	110/7206	5.73822667924e-13
ko04723	Retrograde endocannabinoid signaling	35/397	175/7206	1.35481113367e-11
ko04721	Synaptic vesicle cycle	22/397	80/7206	1.59352326209e-10
ko05031	Amphetamine addiction	23/397	91/7206	3.88189124905e-10
ko04726	Serotonergic synapse	28/397	137/7206	9.73132460226e-10
ko04720	Long-term potentiation	23/397	99/7206	2.33843427015e-09
ko04911	Insulin secretion	24/397	117/7206	1.47369487018e-08
ko05030	Cocaine addiction	18/397	73/7206	4.9701858894e-08
ko04024	cAMP signaling pathway	38/397	279/7206	2.50009477532e-07
ko04020	Calcium signaling pathway	36/397	265/7206	5.75045440309e-07
ko04725	Cholinergic synapse	25/397	160/7206	1.81794902423e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	16/397	74/7206	1.87761105823e-06
ko04261	Adrenergic signaling in cardiomyocytes	29/397	205/7206	2.2138110539e-06
ko04921	Oxytocin signaling pathway	29/397	209/7206	3.29247920027e-06
ko04742	Taste transduction	14/397	61/7206	3.93628643922e-06
ko04730	Long-term depression	15/397	78/7206	1.79330555481e-05
ko04925	Aldosterone synthesis and secretion	17/397	105/7206	5.23307372404e-05
ko04970	Salivary secretion	16/397	95/7206	5.29840087955e-05
ko04010	MAPK signaling pathway	33/397	321/7206	0.000601156483155
ko04924	Renin secretion	13/397	86/7206	0.000779199258758
ko04971	Gastric acid secretion	14/397	98/7206	0.000882809421083
ko04972	Pancreatic secretion	15/397	111/7206	0.0010536116718
ko04966	Collecting duct acid secretion	6/397	26/7206	0.00241542457929
ko04514	Cell adhesion molecules (CAMs)	16/397	130/7206	0.00257690573694
ko04260	Cardiac muscle contraction	13/397	98/7206	0.00264266236723
ko05322	Systemic lupus erythematosus	1/397	151/7206	0.00329307341969
ko05034	Alcoholism	24/397	238/7206	0.00353583487073
ko04072	Phospholipase D signaling pathway	21/397	197/7206	0.00366305226719
ko05010	Alzheimer's disease	21/397	202/7206	0.0043834821686
ko04961	Endocrine and other factor-regulated calcium reabsorption	9/397	59/7206	0.00461458494478
ko03040	Spliceosome	1/397	145/7206	0.00485652589234
ko04540	Gap junction	15/397	128/7206	0.00502428537629
ko04750	Inflammatory mediator regulation of TRP channels	14/397	122/7206	0.00790375766601
ko04022	cGMP-PKG signaling pathway	21/397	216/7206	0.00959793993935
ko04070	Phosphatidylinositol signaling system	13/397	112/7206	0.00999897619189
ko05203	Viral carcinogenesis	6/397	277/7206	0.0100002713664
ko04621	NOD-like receptor signaling pathway	2/397	157/7206	0.0122900299529
ko04114	Oocyte meiosis	15/397	139/7206	0.0125485495232
ko05205	Proteoglycans in cancer	6/397	271/7206	0.0135752621358
ko04626	Plant-pathogen interaction	4/397	18/7206	0.014991947073
ko04014	Ras signaling pathway	25/397	279/7206	0.0151912804856
ko04745	Phototransduction - fly	6/397	38/7206	0.0165995455074
ko05169	Epstein-Barr virus infection	4/397	206/7206	0.0189616035716
ko04964	Proximal tubule bicarbonate reclamation	5/397	29/7206	0.0196566879098
ko05110	Vibrio cholerae infection	8/397	63/7206	0.0214660492201
ko05161	Hepatitis B	3/397	173/7206	0.0262458288764
ko05215	Prostate cancer	1/397	111/7206	0.0320378931362
ko05166	HTLV-I infection	8/397	292/7206	0.0349373698899
ko04120	Ubiquitin mediated proteolysis	2/397	138/7206	0.0352238499498
ko05200	Pathways in cancer	17/397	492/7206	0.0399671172152
ko04510	Focal adhesion	6/397	240/7206	0.0420361972515
ko04744	Phototransduction	5/397	36/7206	0.0456692452899
ko04210	Apoptosis	4/397	180/7206	0.046715668633
ko04932	Non-alcoholic fatty liver disease (NAFLD)	4/397	182/7206	0.0468754937312
ko04141	Protein processing in endoplasmic reticulum	4/397	184/7206	0.0473220925273