ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 35/372 191/7206 2.85718264445e-11 ko04380 Osteoclast differentiation 23/372 134/7206 2.79947699662e-07 ko04621 NOD-like receptor signaling pathway 23/372 157/7206 4.85313602895e-06 ko00643 Styrene degradation 4/372 4/7206 6.99406361039e-06 ko04064 NF-kappa B signaling pathway 16/372 96/7206 2.74269724112e-05 ko00350 Tyrosine metabolism 9/372 33/7206 3.01742229908e-05 ko00140 Steroid hormone biosynthesis 10/372 41/7206 3.16632134028e-05 ko04668 TNF signaling pathway 18/372 120/7206 3.81881391632e-05 ko05164 Influenza A 22/372 167/7206 4.2973860015e-05 ko04610 Complement and coagulation cascades 14/372 79/7206 4.31492447736e-05 ko05034 Alcoholism 1/372 238/7206 7.19333013452e-05 ko04672 Intestinal immune network for IgA production 8/372 37/7206 0.000482189195793 ko05321 Inflammatory bowel disease (IBD) 10/372 56/7206 0.000502859862543 ko00960 Tropane, piperidine and pyridine alkaloid biosynthesis 3/372 4/7206 0.000525123393847 ko04933 AGE-RAGE signaling pathway in diabetic complications 17/372 135/7206 0.000542481640305 ko04512 ECM-receptor interaction 12/372 79/7206 0.000665453435798 ko04623 Cytosolic DNA-sensing pathway 8/372 41/7206 0.000995893380609 ko05162 Measles 15/372 120/7206 0.00122652170239 ko04723 Retrograde endocannabinoid signaling 1/372 175/7206 0.00154991286821 ko05133 Pertussis 12/372 87/7206 0.0015891178847 ko04660 T cell receptor signaling pathway 15/372 124/7206 0.00171410349601 ko04620 Toll-like receptor signaling pathway 13/372 100/7206 0.00178715573896 ko05323 Rheumatoid arthritis 12/372 89/7206 0.00193832154686 ko05150 Staphylococcus aureus infection 7/372 36/7206 0.00209948854989 ko03013 RNA transport 1/372 166/7206 0.00226263409346 ko05160 Hepatitis C 17/372 153/7206 0.00248862976595 ko00120 Primary bile acid biosynthesis 5/372 20/7206 0.00290588137412 ko05145 Toxoplasmosis 15/372 126/7206 0.00319720844812 ko05340 Primary immunodeficiency 6/372 30/7206 0.00375456584024 ko04650 Natural killer cell mediated cytotoxicity 12/372 97/7206 0.00401881066617 ko04630 Jak-STAT signaling pathway 15/372 132/7206 0.00403744662217 ko04622 RIG-I-like receptor signaling pathway 9/372 62/7206 0.00422105398684 ko00590 Arachidonic acid metabolism 8/372 52/7206 0.00478197298527 ko00051 Fructose and mannose metabolism 7/372 42/7206 0.00520064155807 ko04611 Platelet activation 17/372 163/7206 0.00591334885518 ko04728 Dopaminergic synapse 2/372 185/7206 0.0062202572142 ko00480 Glutathione metabolism 8/372 55/7206 0.00676481139777 ko05167 Kaposi's sarcoma-associated herpesvirus infection 19/372 191/7206 0.00680667577209 ko04110 Cell cycle 1/372 145/7206 0.00701243893033 ko05168 Herpes simplex infection 18/372 182/7206 0.00942793261782 ko00360 Phenylalanine metabolism 4/372 17/7206 0.0097310204664 ko04726 Serotonergic synapse 1/372 137/7206 0.0101642366229 ko00982 Drug metabolism - cytochrome P450 6/372 37/7206 0.0108500387992 ko04666 Fc gamma R-mediated phagocytosis 13/372 122/7206 0.0114107994861 ko00950 Isoquinoline alkaloid biosynthesis 3/372 10/7206 0.0124806327414 ko04657 IL-17 signaling pathway 10/372 87/7206 0.0136999908478 ko05140 Leishmaniasis 9/372 75/7206 0.014538498586 ko00980 Metabolism of xenobiotics by cytochrome P450 6/372 40/7206 0.0157398081895 ko04510 Focal adhesion 21/372 240/7206 0.0165416990942 ko05132 Salmonella infection 11/372 98/7206 0.0171743002086 ko00565 Ether lipid metabolism 6/372 42/7206 0.0197383266485 ko05418 Fluid shear stress and atherosclerosis 16/372 173/7206 0.0219193997544 ko04662 B cell receptor signaling pathway 10/372 88/7206 0.0239264181407 ko00400 Phenylalanine, tyrosine and tryptophan biosynthesis 2/372 5/7206 0.023955011855 ko04724 Glutamatergic synapse 2/372 152/7206 0.024648798669 ko04217 Necroptosis 16/372 178/7206 0.0254687839932 ko04310 Wnt signaling pathway 3/372 181/7206 0.0258267102322 ko05144 Malaria 6/372 45/7206 0.0269488633168 ko04974 Protein digestion and absorption 10/372 96/7206 0.0316766814782 ko05204 Chemical carcinogenesis 6/372 48/7206 0.0357194401004 ko05131 Shigellosis 9/372 82/7206 0.0374230165398 ko05152 Tuberculosis 16/372 187/7206 0.0427651772555 ko05142 Chagas disease (American trypanosomiasis) 12/372 130/7206 0.043564655804 ko04640 Hematopoietic cell lineage 7/372 64/7206 0.0457493829169 ko04727 GABAergic synapse 1/372 110/7206 0.0459263893659 ko04713 Circadian entrainment 2/372 136/7206 0.0483441533019 ko04550 Signaling pathways regulating pluripotency of stem cells 3/372 165/7206 0.0486533891092 ko04114 Oocyte meiosis 2/372 139/7206 0.0493604754149