ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko03040	Spliceosome	94/812	145/7206	1.11265617126e-54
ko03013	RNA transport	79/812	166/7206	1.54930973905e-32
ko03008	Ribosome biogenesis in eukaryotes	45/812	79/7206	4.18009056524e-23
ko04110	Cell cycle	62/812	145/7206	1.42725350089e-22
ko03460	Fanconi anemia pathway	34/812	51/7206	6.91732619326e-21
ko03030	DNA replication	29/812	38/7206	1.21721187205e-20
ko03440	Homologous recombination	30/812	41/7206	2.0595330859e-20
ko05322	Systemic lupus erythematosus	59/812	151/7206	3.4129669891e-19
ko04111	Cell cycle - yeast	44/812	90/7206	4.110570272e-19
ko03420	Nucleotide excision repair	26/812	46/7206	9.41772303409e-14
ko03430	Mismatch repair	17/812	22/7206	9.9476467477e-13
ko04113	Meiosis - yeast	31/812	70/7206	2.23871478901e-12
ko00240	Pyrimidine metabolism	40/812	110/7206	3.35418655386e-12
ko04144	Endocytosis	6/812	342/7206	1.60311692215e-11
ko03022	Basal transcription factors	23/812	44/7206	2.3000690247e-11
ko05034	Alcoholism	62/812	238/7206	9.45977381892e-11
ko03015	mRNA surveillance pathway	34/812	93/7206	1.22607656381e-10
ko03018	RNA degradation	32/812	84/7206	1.25138438952e-10
ko05203	Viral carcinogenesis	65/812	277/7206	4.61970361984e-09
ko03020	RNA polymerase	16/812	29/7206	9.63794124154e-09
ko04024	cAMP signaling pathway	6/812	279/7206	1.09688606912e-08
ko05010	Alzheimer's disease	3/812	202/7206	1.79972907181e-07
ko03410	Base excision repair	17/812	38/7206	1.87258867782e-07
ko04022	cGMP-PKG signaling pathway	4/812	216/7206	2.63506546466e-07
ko04151	PI3K-Akt signaling pathway	16/812	390/7206	3.84057056142e-07
ko04270	Vascular smooth muscle contraction	1/812	154/7206	3.99540957849e-07
ko04060	Cytokine-cytokine receptor interaction	3/812	191/7206	5.71785718926e-07
ko04261	Adrenergic signaling in cardiomyocytes	4/812	205/7206	8.17945187468e-07
ko04015	Rap1 signaling pathway	9/812	278/7206	1.47575955523e-06
ko04921	Oxytocin signaling pathway	5/812	209/7206	2.20885916478e-06
ko04723	Retrograde endocannabinoid signaling	3/812	175/7206	2.54568707791e-06
ko04510	Focal adhesion	7/812	240/7206	3.33347965021e-06
ko04724	Glutamatergic synapse	2/812	152/7206	3.52782234248e-06
ko04810	Regulation of actin cytoskeleton	9/812	264/7206	5.87185281882e-06
ko00190	Oxidative phosphorylation	1/812	127/7206	6.43811033462e-06
ko04932	Non-alcoholic fatty liver disease (NAFLD)	4/812	182/7206	7.48370691675e-06
ko04010	MAPK signaling pathway	14/812	321/7206	1.22144634533e-05
ko04621	NOD-like receptor signaling pathway	3/812	157/7206	1.70407785094e-05
ko04911	Insulin secretion	1/812	117/7206	2.18310814239e-05
ko04713	Circadian entrainment	2/812	136/7206	2.54162828912e-05
ko05012	Parkinson's disease	3/812	155/7206	2.60181678134e-05
ko04728	Dopaminergic synapse	5/812	185/7206	2.77070704078e-05
ko04070	Phosphatidylinositol signaling system	1/812	112/7206	3.24106295465e-05
ko05414	Dilated cardiomyopathy	1/812	112/7206	3.24106295465e-05
ko04014	Ras signaling pathway	12/812	279/7206	4.27316899735e-05
ko01200	Carbon metabolism	2/812	128/7206	5.41239409847e-05
ko04725	Cholinergic synapse	4/812	160/7206	6.69360359712e-05
ko05152	Tuberculosis	6/812	187/7206	8.98720128403e-05
ko03060	Protein export	10/812	23/7206	9.0327571774e-05
ko04062	Chemokine signaling pathway	7/812	201/7206	9.82214059119e-05
ko04668	TNF signaling pathway	2/812	120/7206	0.000116036725327
ko04750	Inflammatory mediator regulation of TRP channels	2/812	122/7206	0.000120072165082
ko04072	Phospholipase D signaling pathway	7/812	197/7206	0.00013658284112
ko04380	Osteoclast differentiation	3/812	134/7206	0.000157975277593
ko04971	Gastric acid secretion	1/812	98/7206	0.00016075008331
ko05410	Hypertrophic cardiomyopathy (HCM)	1/812	100/7206	0.000165446425245
ko04611	Platelet activation	5/812	163/7206	0.000226710494987
ko05142	Chagas disease (American trypanosomiasis)	3/812	130/7206	0.000228349889294
ko04514	Cell adhesion molecules (CAMs)	3/812	130/7206	0.000228349889294
ko04974	Protein digestion and absorption	1/812	96/7206	0.000243268355807
ko05031	Amphetamine addiction	1/812	91/7206	0.000356251156719
ko04114	Oocyte meiosis	30/812	139/7206	0.00036047564115
ko04727	GABAergic synapse	2/812	110/7206	0.000365949252215
ko05032	Morphine addiction	2/812	110/7206	0.000365949252215
ko04972	Pancreatic secretion	2/812	111/7206	0.000373958882406
ko05145	Toxoplasmosis	3/812	126/7206	0.000499369544385
ko04659	Th17 cell differentiation	2/812	106/7206	0.000531789189557
ko04146	Peroxisome	1/812	89/7206	0.000539965564694
ko00562	Inositol phosphate metabolism	1/812	89/7206	0.000539965564694
ko04931	Insulin resistance	4/812	137/7206	0.000560085643306
ko04726	Serotonergic synapse	4/812	137/7206	0.000560085643306
ko03450	Non-homologous end-joining	7/812	15/7206	0.000639789854967
ko04371	Apelin signaling pathway	7/812	177/7206	0.000693070216793
ko04666	Fc gamma R-mediated phagocytosis	3/812	122/7206	0.000707798977672
ko04924	Renin secretion	1/812	86/7206	0.000816324100522
ko04530	Tight junction	11/812	228/7206	0.00088456796295
ko04120	Ubiquitin mediated proteolysis	29/812	138/7206	0.0009028414806
ko04915	Estrogen signaling pathway	4/812	131/7206	0.00113521246121
ko00230	Purine metabolism	37/812	194/7206	0.00114587644379
ko04620	Toll-like receptor signaling pathway	2/812	100/7206	0.00115089918285
ko04630	Jak-STAT signaling pathway	4/812	132/7206	0.00116105048735
ko04721	Synaptic vesicle cycle	1/812	80/7206	0.00116879015527
ko04360	Axon guidance	12/812	233/7206	0.00148144759789
ko05205	Proteoglycans in cancer	15/812	271/7206	0.00159499116155
ko04658	Th1 and Th2 cell differentiation	2/812	96/7206	0.00165636223107
ko04912	GnRH signaling pathway	4/812	122/7206	0.00222138560913
ko04933	AGE-RAGE signaling pathway in diabetic complications	5/812	135/7206	0.00236649183105
ko05030	Cocaine addiction	1/812	73/7206	0.00256168196563
ko00010	Glycolysis / Gluconeogenesis	1/812	74/7206	0.00257431533551
ko05134	Legionellosis	1/812	74/7206	0.00257431533551
ko05140	Leishmaniasis	1/812	75/7206	0.0026309651101
ko04914	Progesterone-mediated oocyte maturation	22/812	104/7206	0.00280361244736
ko04925	Aldosterone synthesis and secretion	3/812	105/7206	0.00282329292551
ko05200	Pathways in cancer	36/812	492/7206	0.00308002314759
ko04152	AMPK signaling pathway	7/812	161/7206	0.00337643981506
ko05166	HTLV-I infection	49/812	292/7206	0.0043532572216
ko04922	Glucagon signaling pathway	5/812	128/7206	0.00452152840122
ko01230	Biosynthesis of amino acids	2/812	85/7206	0.00500019099189
ko04650	Natural killer cell mediated cytotoxicity	3/812	97/7206	0.00567420791598
ko04670	Leukocyte transendothelial migration	7/812	151/7206	0.00603311273133
ko04660	T cell receptor signaling pathway	5/812	124/7206	0.00622681261598
ko04640	Hematopoietic cell lineage	1/812	64/7206	0.00840763330835
ko05231	Choline metabolism in cancer	6/812	134/7206	0.0084120909733
ko04066	HIF-1 signaling pathway	5/812	123/7206	0.00878012809769
ko05202	Transcriptional misregulation in cancer	33/812	188/7206	0.00957450469776
ko04923	Regulation of lipolysis in adipocytes	2/812	77/7206	0.0102418983989
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	2/812	79/7206	0.0106877453653
ko04512	ECM-receptor interaction	2/812	79/7206	0.0106877453653
ko04218	Cellular senescence	31/812	177/7206	0.0111414977502
ko05120	Epithelial cell signaling in Helicobacter pylori infection	3/812	92/7206	0.0115482469937
ko04742	Taste transduction	1/812	61/7206	0.0125893694831
ko05167	Kaposi's sarcoma-associated herpesvirus infection	11/812	191/7206	0.0141769630392
ko04540	Gap junction	6/812	128/7206	0.0155366767644
ko05133	Pertussis	3/812	87/7206	0.0158822944392
ko04662	B cell receptor signaling pathway	3/812	88/7206	0.0161050902415
ko04720	Long-term potentiation	4/812	99/7206	0.0161629771287
ko05323	Rheumatoid arthritis	3/812	89/7206	0.0164838884582
ko05168	Herpes simplex infection	31/812	182/7206	0.0171118274141
ko04142	Lysosome	8/812	151/7206	0.018277441579
ko04962	Vasopressin-regulated water reabsorption	1/812	58/7206	0.0188972536208
ko05418	Fluid shear stress and atherosclerosis	10/812	173/7206	0.0199722051353
ko05132	Salmonella infection	4/812	98/7206	0.0226995662029
ko05169	Epstein-Barr virus infection	34/812	206/7206	0.0245018273329
ko04068	FoxO signaling pathway	10/812	167/7206	0.0256175728873
ko04930	Type II diabetes mellitus	1/812	54/7206	0.0272932190663
ko05162	Measles	6/812	120/7206	0.0277760473247
ko04730	Long-term depression	3/812	78/7206	0.0308291845085
ko04712	Circadian rhythm - plant	3/812	7/7206	0.0352229158862
ko04910	Insulin signaling pathway	11/812	172/7206	0.0379755868788
ko05204	Chemical carcinogenesis	1/812	48/7206	0.0382370271272
ko04622	RIG-I-like receptor signaling pathway	2/812	62/7206	0.0422366108844
ko04722	Neurotrophin signaling pathway	10/812	160/7206	0.0424254196978
ko00561	Glycerolipid metabolism	2/812	63/7206	0.0427242810149
ko04071	Sphingolipid signaling pathway	10/812	162/7206	0.0430411185187
ko05130	Pathogenic Escherichia coli infection	3/812	77/7206	0.0436316452865