ko pathway ratio_in_study ratio_in_pop p_value ko04621 NOD-like receptor signaling pathway 24/279 157/7206 5.97006489941e-09 ko05164 Influenza A 24/279 167/7206 2.08115899062e-08 ko04668 TNF signaling pathway 20/279 120/7206 2.60537865429e-08 ko04064 NF-kappa B signaling pathway 16/279 96/7206 6.72397418889e-07 ko04380 Osteoclast differentiation 19/279 134/7206 8.07149166709e-07 ko04080 Neuroactive ligand-receptor interaction 2/279 423/7206 1.15285140918e-05 ko04660 T cell receptor signaling pathway 16/279 124/7206 2.07279076306e-05 ko04137 Mitophagy - animal 12/279 82/7206 6.56568065175e-05 ko04620 Toll-like receptor signaling pathway 13/279 100/7206 0.000114961852134 ko04060 Cytokine-cytokine receptor interaction 19/279 191/7206 0.000139217075967 ko05167 Kaposi's sarcoma-associated herpesvirus infection 19/279 191/7206 0.000139217075967 ko04623 Cytosolic DNA-sensing pathway 8/279 41/7206 0.000143234952867 ko00051 Fructose and mannose metabolism 8/279 42/7206 0.000171084991484 ko05162 Measles 14/279 120/7206 0.000205046404317 ko05168 Herpes simplex infection 18/279 182/7206 0.000224306647733 ko05150 Staphylococcus aureus infection 7/279 36/7206 0.00038421023986 ko04217 Necroptosis 17/279 178/7206 0.000503996970715 ko04622 RIG-I-like receptor signaling pathway 9/279 62/7206 0.000573981804438 ko05161 Hepatitis B 16/279 173/7206 0.00103958070537 ko04650 Natural killer cell mediated cytotoxicity 11/279 97/7206 0.00123809966853 ko05133 Pertussis 10/279 87/7206 0.00184653093459 ko05323 Rheumatoid arthritis 10/279 89/7206 0.0021930134985 ko04210 Apoptosis 16/279 180/7206 0.00232920556846 ko05160 Hepatitis C 14/279 153/7206 0.00233800159564 ko04672 Intestinal immune network for IgA production 6/279 37/7206 0.00269572340848 ko05145 Toxoplasmosis 12/279 126/7206 0.00339583515068 ko05131 Shigellosis 9/279 82/7206 0.00422648581599 ko04630 Jak-STAT signaling pathway 12/279 132/7206 0.00495746745073 ko05321 Inflammatory bowel disease (IBD) 7/279 56/7206 0.0055202572545 ko04136 Autophagy - other 5/279 31/7206 0.00623609383953 ko00120 Primary bile acid biosynthesis 4/279 20/7206 0.00652206221233 ko05134 Legionellosis 8/279 74/7206 0.0075064211014 ko04062 Chemokine signaling pathway 16/279 201/7206 0.00777786309659 ko05140 Leishmaniasis 8/279 75/7206 0.00812906506802 ko00643 Styrene degradation 2/279 4/7206 0.0085104540146 ko05120 Epithelial cell signaling in Helicobacter pylori infection 9/279 92/7206 0.00896438310944 ko04215 Apoptosis - multiple species 6/279 47/7206 0.00901914138667 ko05034 Alcoholism 2/279 238/7206 0.00912150343624 ko04610 Complement and coagulation cascades 8/279 79/7206 0.0110132747992 ko04658 Th1 and Th2 cell differentiation 9/279 96/7206 0.0117066299982 ko05330 Allograft rejection 4/279 24/7206 0.0126704603473 ko05152 Tuberculosis 14/279 187/7206 0.0184169284142 ko04917 Prolactin signaling pathway 8/279 87/7206 0.0189516595068 ko04662 B cell receptor signaling pathway 8/279 88/7206 0.0201728998444 ko04710 Circadian rhythm 5/279 43/7206 0.0242763868313 ko05320 Autoimmune thyroid disease 4/279 29/7206 0.0243610596298 ko05340 Primary immunodeficiency 4/279 30/7206 0.0272785198878 ko05332 Graft-versus-host disease 3/279 18/7206 0.0304478160019 ko05142 Chagas disease (American trypanosomiasis) 10/279 130/7206 0.0345376336596 ko04390 Hippo signaling pathway 2/279 188/7206 0.035048580411 ko00592 alpha-Linolenic acid metabolism 3/279 19/7206 0.0351482495168 ko00740 Riboflavin metabolism 2/279 8/7206 0.0358394910647 ko04068 FoxO signaling pathway 12/279 167/7206 0.0383068856722 ko04931 Insulin resistance 10/279 137/7206 0.043661872352 ko03040 Spliceosome 1/279 145/7206 0.046111247076 ko04110 Cell cycle 1/279 145/7206 0.046111247076 ko04020 Calcium signaling pathway 4/279 265/7206 0.0488153130177 ko00590 Arachidonic acid metabolism 5/279 52/7206 0.0496335138022