ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	95/470	423/7206	8.20107975397e-29
ko04724	Glutamatergic synapse	43/470	152/7206	3.41025890251e-17
ko04727	GABAergic synapse	32/470	110/7206	1.88577618974e-13
ko04713	Circadian entrainment	34/470	136/7206	3.93923331775e-12
ko05032	Morphine addiction	30/470	110/7206	6.91267679199e-12
ko04723	Retrograde endocannabinoid signaling	38/470	175/7206	2.14576543607e-11
ko04728	Dopaminergic synapse	39/470	185/7206	3.02478031936e-11
ko04726	Serotonergic synapse	31/470	137/7206	5.47693560523e-10
ko04911	Insulin secretion	28/470	117/7206	9.82647458367e-10
ko04721	Synaptic vesicle cycle	22/470	80/7206	3.95957232551e-09
ko04020	Calcium signaling pathway	44/470	265/7206	5.35003125537e-09
ko05033	Nicotine addiction	18/470	56/7206	6.91545883409e-09
ko05031	Amphetamine addiction	23/470	91/7206	1.03871449502e-08
ko04720	Long-term potentiation	24/470	99/7206	1.20826406354e-08
ko04024	cAMP signaling pathway	45/470	279/7206	1.35905490748e-08
ko04921	Oxytocin signaling pathway	37/470	209/7206	1.64069964119e-08
ko04742	Taste transduction	18/470	61/7206	3.14652892517e-08
ko04725	Cholinergic synapse	30/470	160/7206	1.04842224384e-07
ko04925	Aldosterone synthesis and secretion	22/470	105/7206	7.6716659236e-07
ko05030	Cocaine addiction	17/470	73/7206	3.05413723415e-06
ko04070	Phosphatidylinositol signaling system	21/470	112/7206	8.83943310589e-06
ko04966	Collecting duct acid secretion	9/470	26/7206	2.27315840212e-05
ko04072	Phospholipase D signaling pathway	29/470	197/7206	2.80885363071e-05
ko04970	Salivary secretion	18/470	95/7206	3.33714836089e-05
ko04730	Long-term depression	15/470	78/7206	0.000125882323319
ko05169	Epstein-Barr virus infection	2/470	206/7206	0.000155629686065
ko05110	Vibrio cholerae infection	13/470	63/7206	0.000168506654926
ko04971	Gastric acid secretion	17/470	98/7206	0.000172555224149
ko04972	Pancreatic secretion	18/470	111/7206	0.000269917436913
ko05164	Influenza A	1/470	167/7206	0.000337167788363
ko04744	Phototransduction	9/470	36/7206	0.000381025176737
ko04261	Adrenergic signaling in cardiomyocytes	27/470	205/7206	0.000437627797979
ko05168	Herpes simplex infection	2/470	182/7206	0.000682517450113
ko04540	Gap junction	19/470	128/7206	0.000749288916025
ko00010	Glycolysis / Gluconeogenesis	13/470	74/7206	0.000872014337529
ko04915	Estrogen signaling pathway	19/470	131/7206	0.000916743442518
ko04750	Inflammatory mediator regulation of TRP channels	18/470	122/7206	0.00111923066459
ko00680	Methane metabolism	8/470	34/7206	0.0012375416336
ko04550	Signaling pathways regulating pluripotency of stem cells	2/470	165/7206	0.00205121913949
ko04010	MAPK signaling pathway	35/470	321/7206	0.00242448639067
ko04060	Cytokine-cytokine receptor interaction	3/470	191/7206	0.00251760384264
ko04745	Phototransduction - fly	8/470	38/7206	0.00264834988061
ko05014	Amyotrophic lateral sclerosis (ALS)	12/470	74/7206	0.00276699415753
ko04924	Renin secretion	13/470	86/7206	0.00354798730049
ko00030	Pentose phosphate pathway	7/470	32/7206	0.00387142411133
ko03040	Spliceosome	2/470	145/7206	0.00593075428789
ko04110	Cell cycle	2/470	145/7206	0.00593075428789
ko05323	Rheumatoid arthritis	13/470	89/7206	0.00717537502898
ko00562	Inositol phosphate metabolism	13/470	89/7206	0.00717537502898
ko04510	Focal adhesion	6/470	240/7206	0.00727749956456
ko05120	Epithelial cell signaling in Helicobacter pylori infection	13/470	92/7206	0.00831390512812
ko04120	Ubiquitin mediated proteolysis	2/470	138/7206	0.00841858703823
ko05203	Viral carcinogenesis	8/470	277/7206	0.0088549474101
ko05202	Transcriptional misregulation in cancer	4/470	188/7206	0.0100139229713
ko04922	Glucagon signaling pathway	16/470	128/7206	0.0104269473827
ko04022	cGMP-PKG signaling pathway	24/470	216/7206	0.0107887055517
ko04918	Thyroid hormone synthesis	12/470	86/7206	0.0124180308564
ko04371	Apelin signaling pathway	20/470	177/7206	0.013401258102
ko04940	Type I diabetes mellitus	6/470	32/7206	0.0158136889878
ko05145	Toxoplasmosis	2/470	126/7206	0.0169263182239
ko04910	Insulin signaling pathway	4/470	172/7206	0.0184571873129
ko05224	Breast cancer	4/470	174/7206	0.0185937981325
ko05160	Hepatitis C	3/470	153/7206	0.018733500527
ko05231	Choline metabolism in cancer	16/470	134/7206	0.019393692676
ko04710	Circadian rhythm	7/470	43/7206	0.0199851858053
ko00950	Isoquinoline alkaloid biosynthesis	3/470	10/7206	0.0234327707955
ko00650	Butanoate metabolism	5/470	26/7206	0.0242907469634
ko01230	Biosynthesis of amino acids	11/470	85/7206	0.0246746882886
ko00230	Purine metabolism	21/470	194/7206	0.0253272912901
ko05222	Small cell lung cancer	1/470	89/7206	0.0297108734349
ko05034	Alcoholism	24/470	238/7206	0.0315374734523
ko05205	Proteoglycans in cancer	9/470	271/7206	0.0317584069846
ko04923	Regulation of lipolysis in adipocytes	10/470	77/7206	0.0325072979781
ko04141	Protein processing in endoplasmic reticulum	5/470	184/7206	0.0328596601866
ko04931	Insulin resistance	3/470	137/7206	0.0346858848744
ko00250	Alanine, aspartate and glutamate metabolism	6/470	38/7206	0.0347080114311
ko04260	Cardiac muscle contraction	12/470	98/7206	0.0351933387038
ko04912	GnRH signaling pathway	14/470	122/7206	0.038685922587
ko05218	Melanoma	1/470	85/7206	0.043450304312
ko05220	Chronic myeloid leukemia	1/470	85/7206	0.043450304312
ko05206	MicroRNAs in cancer	5/470	177/7206	0.043712487444
ko00190	Oxidative phosphorylation	14/470	127/7206	0.0453941531796
ko01200	Carbon metabolism	14/470	128/7206	0.0470711212419
ko00240	Pyrimidine metabolism	2/470	110/7206	0.0481943133504
ko05215	Prostate cancer	2/470	111/7206	0.0488588670352
ko05414	Dilated cardiomyopathy	13/470	112/7206	0.0496655641855