ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	153/819	423/7206	4.6251862808e-44
ko04724	Glutamatergic synapse	78/819	152/7206	8.32048281399e-35
ko05033	Nicotine addiction	43/819	56/7206	3.99836262084e-30
ko05032	Morphine addiction	56/819	110/7206	5.6430770223e-25
ko04727	GABAergic synapse	54/819	110/7206	3.91060976128e-23
ko04713	Circadian entrainment	58/819	136/7206	6.37213972265e-21
ko04721	Synaptic vesicle cycle	43/819	80/7206	1.23520952395e-20
ko04723	Retrograde endocannabinoid signaling	66/819	175/7206	3.63339766695e-20
ko04728	Dopaminergic synapse	66/819	185/7206	1.13599723419e-18
ko04725	Cholinergic synapse	58/819	160/7206	6.64659409838e-17
ko04726	Serotonergic synapse	51/819	137/7206	1.49932827834e-15
ko04742	Taste transduction	31/819	61/7206	2.52718131897e-14
ko04024	cAMP signaling pathway	76/819	279/7206	1.14577356709e-13
ko04744	Phototransduction	22/819	36/7206	1.02586396839e-12
ko04911	Insulin secretion	42/819	117/7206	2.10156268164e-12
ko04921	Oxytocin signaling pathway	60/819	209/7206	3.06147353254e-12
ko04020	Calcium signaling pathway	65/819	265/7206	7.38126329868e-10
ko05031	Amphetamine addiction	31/819	91/7206	7.34996930478e-09
ko05030	Cocaine addiction	27/819	73/7206	9.15752507065e-09
ko04261	Adrenergic signaling in cardiomyocytes	52/819	205/7206	1.59428472188e-08
ko05014	Amyotrophic lateral sclerosis (ALS)	26/819	74/7206	5.88687066651e-08
ko04720	Long-term potentiation	31/819	99/7206	6.92783660209e-08
ko04970	Salivary secretion	29/819	95/7206	3.37643000446e-07
ko03040	Spliceosome	1/819	145/7206	8.64329841189e-07
ko05203	Viral carcinogenesis	9/819	277/7206	1.01700235832e-06
ko04120	Ubiquitin mediated proteolysis	1/819	138/7206	1.95513968534e-06
ko05164	Influenza A	3/819	167/7206	5.48614723779e-06
ko04730	Long-term depression	23/819	78/7206	1.05497164395e-05
ko05322	Systemic lupus erythematosus	3/819	151/7206	2.44105370791e-05
ko05168	Herpes simplex infection	5/819	182/7206	2.73283052768e-05
ko04260	Cardiac muscle contraction	26/819	98/7206	2.99388820728e-05
ko04010	MAPK signaling pathway	61/819	321/7206	4.33317930497e-05
ko04740	Olfactory transduction	22/819	80/7206	5.40044359865e-05
ko04966	Collecting duct acid secretion	11/819	26/7206	5.88321780945e-05
ko04060	Cytokine-cytokine receptor interaction	6/819	191/7206	6.53570100623e-05
ko04971	Gastric acid secretion	25/819	98/7206	7.41802062835e-05
ko05162	Measles	2/819	120/7206	0.000116269576501
ko05205	Proteoglycans in cancer	13/819	271/7206	0.000187532108828
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	21/819	79/7206	0.000203973828227
ko04540	Gap junction	29/819	128/7206	0.000209387984549
ko04972	Pancreatic secretion	26/819	111/7206	0.000242668941149
ko04925	Aldosterone synthesis and secretion	25/819	105/7206	0.00026368624128
ko04621	NOD-like receptor signaling pathway	5/819	157/7206	0.00031485556289
ko03013	RNA transport	6/819	166/7206	0.000478411867522
ko04514	Cell adhesion molecules (CAMs)	28/819	130/7206	0.000693124442745
ko04072	Phospholipase D signaling pathway	38/819	197/7206	0.000881640565976
ko04964	Proximal tubule bicarbonate reclamation	10/819	29/7206	0.000900463649245
ko04141	Protein processing in endoplasmic reticulum	8/819	184/7206	0.00131883585971
ko04022	cGMP-PKG signaling pathway	40/819	216/7206	0.00150534775257
ko05169	Epstein-Barr virus infection	10/819	206/7206	0.00165692357324
ko04612	Antigen processing and presentation	1/819	77/7206	0.00173189726102
ko04610	Complement and coagulation cascades	1/819	79/7206	0.00184692099682
ko05110	Vibrio cholerae infection	16/819	63/7206	0.00189506167094
ko05414	Dilated cardiomyopathy	24/819	112/7206	0.00223043508
ko00310	Lysine degradation	1/819	73/7206	0.00255209935608
ko05166	HTLV-I infection	18/819	292/7206	0.00333530180919
ko04976	Bile secretion	18/819	80/7206	0.00387262846106
ko04214	Apoptosis - fly	1/819	72/7206	0.00405613315898
ko04932	Non-alcoholic fatty liver disease (NAFLD)	9/819	182/7206	0.00417410365045
ko04924	Renin secretion	19/819	86/7206	0.00523894791266
ko04064	NF-kappa B signaling pathway	3/819	96/7206	0.00565531648956
ko03008	Ribosome biogenesis in eukaryotes	2/819	79/7206	0.00708102248526
ko05161	Hepatitis B	9/819	173/7206	0.00726599489322
ko04915	Estrogen signaling pathway	25/819	131/7206	0.00793064374372
ko04330	Notch signaling pathway	1/819	62/7206	0.00820836571023
ko04745	Phototransduction - fly	10/819	38/7206	0.00824952484259
ko04668	TNF signaling pathway	5/819	120/7206	0.00852650970419
ko04510	Focal adhesion	15/819	240/7206	0.00937627926771
ko04070	Phosphatidylinositol signaling system	22/819	112/7206	0.00981320649908
ko01524	Platinum drug resistance	2/819	76/7206	0.0101788613734
ko05410	Hypertrophic cardiomyopathy (HCM)	20/819	100/7206	0.010335717605
ko04110	Cell cycle	7/819	145/7206	0.011189194417
ko04146	Peroxisome	3/819	89/7206	0.0112321297794
ko04350	TGF-beta signaling pathway	4/819	103/7206	0.0116788319273
ko04750	Inflammatory mediator regulation of TRP channels	23/819	122/7206	0.0135842203166
ko05418	Fluid shear stress and atherosclerosis	10/819	173/7206	0.0151946595874
ko05140	Leishmaniasis	2/819	75/7206	0.0154020271457
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/819	14/7206	0.0155909153321
ko04014	Ras signaling pathway	45/819	279/7206	0.0156722224143
ko05034	Alcoholism	39/819	238/7206	0.0166535096673
ko00480	Glutathione metabolism	1/819	55/7206	0.0177736111648
ko04961	Endocrine and other factor-regulated calcium reabsorption	13/819	59/7206	0.0202778320583
ko04360	Axon guidance	38/819	233/7206	0.0204970960538
ko05016	Huntington's disease	14/819	215/7206	0.0214655975024
ko04371	Apelin signaling pathway	30/819	177/7206	0.0223669110973
ko00280	Valine, leucine and isoleucine degradation	1/819	54/7206	0.0276826382551
ko04640	Hematopoietic cell lineage	2/819	64/7206	0.0296749827937
ko04062	Chemokine signaling pathway	33/819	201/7206	0.0312673080845
ko05145	Toxoplasmosis	7/819	126/7206	0.0337755360007
ko04142	Lysosome	9/819	151/7206	0.0369290737803
ko05219	Bladder cancer	1/819	48/7206	0.0382237262016
ko04978	Mineral absorption	9/819	40/7206	0.0402902036818
ko05133	Pertussis	4/819	87/7206	0.0413940081452
ko05222	Small cell lung cancer	4/819	89/7206	0.0418447158146
ko04210	Apoptosis	12/819	180/7206	0.0429709890582
ko05120	Epithelial cell signaling in Helicobacter pylori infection	17/819	92/7206	0.0447545169833
ko04626	Plant-pathogen interaction	5/819	18/7206	0.0455419097436
ko05215	Prostate cancer	6/819	111/7206	0.0487317914229